FR3092103B1 - Procédé de fabrication de dispositifs microfluidiques 3D - Google Patents

Procédé de fabrication de dispositifs microfluidiques 3D Download PDF

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Publication number
FR3092103B1
FR3092103B1 FR1900801A FR1900801A FR3092103B1 FR 3092103 B1 FR3092103 B1 FR 3092103B1 FR 1900801 A FR1900801 A FR 1900801A FR 1900801 A FR1900801 A FR 1900801A FR 3092103 B1 FR3092103 B1 FR 3092103B1
Authority
FR
France
Prior art keywords
support
substrate
manufacturing
dimensions
microfluidic devices
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1900801A
Other languages
English (en)
Other versions
FR3092103A1 (fr
Inventor
Florian Larramendy
Thibault Honegger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Netri SAS
Original Assignee
Netri SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR1900801A priority Critical patent/FR3092103B1/fr
Application filed by Netri SAS filed Critical Netri SAS
Priority to JP2021542574A priority patent/JP2022518774A/ja
Priority to EP20705241.6A priority patent/EP3917872A1/fr
Priority to CN202080026012.5A priority patent/CN113646252A/zh
Priority to US17/426,991 priority patent/US20220111381A1/en
Priority to KR1020217027529A priority patent/KR20210124301A/ko
Priority to PCT/FR2020/050097 priority patent/WO2020157412A1/fr
Publication of FR3092103A1 publication Critical patent/FR3092103A1/fr
Application granted granted Critical
Publication of FR3092103B1 publication Critical patent/FR3092103B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
    • B81C99/00—Subject matter not provided for in other groups of this subclass
    • B81C99/0075—Manufacture of substrate-free structures
    • B81C99/0085—Manufacture of substrate-free structures using moulds and master templates, e.g. for hot-embossing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y10/00—Processes of additive manufacturing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00—Products made by additive manufacturing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
    • B81C99/00—Subject matter not provided for in other groups of this subclass
    • B81C99/0075—Manufacture of substrate-free structures
    • B81C99/009—Manufacturing the stamps or the moulds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/12—Specific details about manufacturing devices
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/16—Microfluidic devices; Capillary tubes

Landscapes

  • Engineering & Computer Science (AREA)
  • Manufacturing & Machinery (AREA)
  • Chemical & Material Sciences (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Micromachines (AREA)
  • Moulds For Moulding Plastics Or The Like (AREA)
  • Shaping Of Tube Ends By Bending Or Straightening (AREA)

Abstract

Procédé (100) de fabrication d’un dispositif microfluidique (20), le procédé comprenant une étape de production (101) d’un moule maître (1), le moule-maître (1) comprenant un premier support (2) et un deuxième support (8), le deuxième support comprenant un substrat (3) et des microstructures (4), le substrat (3) ayant une première face et une deuxième face opposée à la première, l’étape de production du moule maître comprenant les sous-étapes suivantes : - réalisation (1011) du deuxième support (8) en formant les microstructures (4) sur la première face du substrat (3) ; - impression (1012) en trois dimensions du premier support (2) sur une imprimante 3D, avec une résine d’impression, les dimensions du premier support(2) étant ajustées aux dimensions du substrat (3) pour contenir le substrat (3); - insertion (1014) du substrat du deuxième support (8) dans le premier support. Figure 1
FR1900801A 2019-01-29 2019-01-29 Procédé de fabrication de dispositifs microfluidiques 3D Active FR3092103B1 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
FR1900801A FR3092103B1 (fr) 2019-01-29 2019-01-29 Procédé de fabrication de dispositifs microfluidiques 3D
EP20705241.6A EP3917872A1 (fr) 2019-01-29 2020-01-23 Procédé de fabrication de dispositifs microfluidiques 3d
CN202080026012.5A CN113646252A (zh) 2019-01-29 2020-01-23 用于制造3d微流体装置的方法
US17/426,991 US20220111381A1 (en) 2019-01-29 2020-01-23 Method for manufacturing 3d microfluidic devices
JP2021542574A JP2022518774A (ja) 2019-01-29 2020-01-23 ３ｄマイクロ流体デバイスの製造方法
KR1020217027529A KR20210124301A (ko) 2019-01-29 2020-01-23 3d 마이크로유체 디바이스의 제조 방법
PCT/FR2020/050097 WO2020157412A1 (fr) 2019-01-29 2020-01-23 Procédé de fabrication de dispositifs microfluidiques 3d

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1900801A FR3092103B1 (fr) 2019-01-29 2019-01-29 Procédé de fabrication de dispositifs microfluidiques 3D
FR1900801 2019-01-29

Publications (2)

Publication Number Publication Date
FR3092103A1 FR3092103A1 (fr) 2020-07-31
FR3092103B1 true FR3092103B1 (fr) 2022-08-05

Family

ID=67107691

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1900801A Active FR3092103B1 (fr) 2019-01-29 2019-01-29 Procédé de fabrication de dispositifs microfluidiques 3D

Country Status (7)

Country Link
US (1) US20220111381A1 (fr)
EP (1) EP3917872A1 (fr)
JP (1) JP2022518774A (fr)
KR (1) KR20210124301A (fr)
CN (1) CN113646252A (fr)
FR (1) FR3092103B1 (fr)
WO (1) WO2020157412A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4116405A1 (fr) * 2021-07-07 2023-01-11 Koninklijke Philips N.V. Dispositif fluidique et son procédé de fabrication

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5932799A (en) * 1997-07-21 1999-08-03 Ysi Incorporated Microfluidic analyzer module
TW200603994A (en) * 2004-07-23 2006-02-01 Hon Hai Prec Ind Co Ltd Nano-imprinting stamp and method for making same
CN100450703C (zh) * 2004-08-26 2009-01-14 台达电子工业股份有限公司 模制成型方法
JP5475761B2 (ja) * 2008-06-20 2014-04-16 スリーエム イノベイティブ プロパティズ カンパニー ポリマー鋳型
CN101592627B (zh) * 2009-03-19 2012-12-05 中国科学院苏州纳米技术与纳米仿生研究所 多通道高灵敏生物传感器的制作集成方法
TW201124256A (en) * 2010-01-07 2011-07-16 Richell Corp Mold for and method of manufacturing small components
US20110236277A1 (en) * 2010-03-24 2011-09-29 Electronics And Telecommunications Research Institute Microfluid control device and method of manufacturing the same
KR101348655B1 (ko) * 2010-03-24 2014-01-08 한국전자통신연구원 미세유체 제어 장치 및 그 제조 방법
CN101962614B (zh) * 2010-08-11 2013-08-07 清华大学 生物芯片及其制备方法
US11826757B2 (en) * 2017-08-02 2023-11-28 Wake Forest University Health Sciences Niches-on-a-chip

Also Published As

Publication number Publication date
EP3917872A1 (fr) 2021-12-08
WO2020157412A1 (fr) 2020-08-06
US20220111381A1 (en) 2022-04-14
JP2022518774A (ja) 2022-03-16
FR3092103A1 (fr) 2020-07-31
KR20210124301A (ko) 2021-10-14
CN113646252A (zh) 2021-11-12

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