FR3080002B1 - Procede de suivi de la viabilite d'un greffon - Google Patents

Procede de suivi de la viabilite d'un greffon Download PDF

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Publication number
FR3080002B1
FR3080002B1 FR1853340A FR1853340A FR3080002B1 FR 3080002 B1 FR3080002 B1 FR 3080002B1 FR 1853340 A FR1853340 A FR 1853340A FR 1853340 A FR1853340 A FR 1853340A FR 3080002 B1 FR3080002 B1 FR 3080002B1
Authority
FR
France
Prior art keywords
graft
composition
viability
monitoring
sealed container
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1853340A
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English (en)
Other versions
FR3080002A1 (fr
Inventor
Franck Zal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hemarina SA
Original Assignee
Hemarina SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hemarina SA filed Critical Hemarina SA
Priority to FR1853340A priority Critical patent/FR3080002B1/fr
Priority to PCT/EP2019/059685 priority patent/WO2019201863A1/fr
Priority to EP19717903.9A priority patent/EP3780954A1/fr
Priority to BR112020021030-7A priority patent/BR112020021030A2/pt
Priority to US17/047,945 priority patent/US20210172900A1/en
Publication of FR3080002A1 publication Critical patent/FR3080002A1/fr
Application granted granted Critical
Publication of FR3080002B1 publication Critical patent/FR3080002B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0236—Mechanical aspects
    • A01N1/0263—Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving, e.g. cool boxes, blood bags or "straws" for cryopreservation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403—Cells and electrode assemblies
    • G01N27/406—Cells and probes with solid electrolytes
    • G01N27/407—Cells and probes with solid electrolytes for investigating or analysing gases
    • G01N27/409—Oxygen concentration cells
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0226—Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0236—Mechanical aspects
    • A01N1/0263—Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving, e.g. cool boxes, blood bags or "straws" for cryopreservation
    • A01N1/0273—Transport containers
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0278—Physical preservation processes
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0236—Mechanical aspects
    • A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
    • A01N1/0247—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components for perfusion, i.e. for circulating fluid through organs, blood vessels or other living parts
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2496/00—Reference solutions for assays of biological material
    • G01N2496/70—Blood gas control solutios containing dissolved oxygen, bicarbonate and the like

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Mechanical Engineering (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

La présente invention a pour objet un procédé de suivi de l'oxygénation d'un greffon, comprenant : a) le mélange d'une solution de préservation d'organe de préférence avec au moins une molécule choisie parmi l'hémoglobine extracellulaire d'Annélides, ses globines et ses protomères de globine, afin d'obtenir une composition, dans un récipient étanche ; b) l'immersion du greffon dans la composition obtenue en a) ; c) l'introduction d'une sonde à oxygène dans la composition obtenue en a), ou dans la composition de l'étape b) ; et d) la fermeture du récipient étanche, les étapes c) et d) étant effectuées simultanément ou dans un ordre indifférent. Elle a également pour objet un procédé de détermination de la viabilité d'un greffon.
FR1853340A 2018-04-17 2018-04-17 Procede de suivi de la viabilite d'un greffon Active FR3080002B1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR1853340A FR3080002B1 (fr) 2018-04-17 2018-04-17 Procede de suivi de la viabilite d'un greffon
PCT/EP2019/059685 WO2019201863A1 (fr) 2018-04-17 2019-04-15 Procédé de suivi de la viabilité d'un greffon
EP19717903.9A EP3780954A1 (fr) 2018-04-17 2019-04-15 Procédé de suivi de la viabilité d'un greffon
BR112020021030-7A BR112020021030A2 (pt) 2018-04-17 2019-04-15 Método de monitoramento da oxigenação de um enxerto e método de determinação da viabilidade de um enxerto
US17/047,945 US20210172900A1 (en) 2018-04-17 2019-04-15 Method for monitoring the viability of a graft

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1853340 2018-04-17
FR1853340A FR3080002B1 (fr) 2018-04-17 2018-04-17 Procede de suivi de la viabilite d'un greffon

Publications (2)

Publication Number Publication Date
FR3080002A1 FR3080002A1 (fr) 2019-10-18
FR3080002B1 true FR3080002B1 (fr) 2020-11-20

Family

ID=62816766

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1853340A Active FR3080002B1 (fr) 2018-04-17 2018-04-17 Procede de suivi de la viabilite d'un greffon

Country Status (5)

Country Link
US (1) US20210172900A1 (fr)
EP (1) EP3780954A1 (fr)
BR (1) BR112020021030A2 (fr)
FR (1) FR3080002B1 (fr)
WO (1) WO2019201863A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024023068A1 (fr) * 2022-07-26 2024-02-01 Hemarina Utilisation d'une molécule d'annélide pour le traitement et/ou la prévention d'au moins une maladie associée à l'activation du complément

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2881723B1 (fr) 2005-02-08 2007-04-27 E3 Cortex Sa Sacoche pour le transport de greffons en vue de transplantation
US11224218B2 (en) * 2009-05-07 2022-01-18 Hemarina Heamoglobin and uses thereof
FR2975869B1 (fr) * 2011-05-31 2017-03-03 Hemarina Composition de preservation d'organe et utilisations
FR2994163B1 (fr) 2012-07-31 2014-08-22 E3 Cortex Conteneur hermetique et procede d'emballage mettant en oeuvre un tel conteneur
US8785116B2 (en) * 2012-08-10 2014-07-22 Paragonix Technologies, Inc. Methods for evaluating the suitability of an organ for transplant

Also Published As

Publication number Publication date
EP3780954A1 (fr) 2021-02-24
US20210172900A1 (en) 2021-06-10
FR3080002A1 (fr) 2019-10-18
WO2019201863A1 (fr) 2019-10-24
BR112020021030A2 (pt) 2021-01-19

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