FR3061659B1 - Composition pharmaceutique comprenant en tant que principe actif une combinaison de d-limoneme, de lupeol et du cinnamaldehyde et/ou de l'epicatechine et/ou du methylhydroxychalcone polymere et/ou d - Google Patents
Composition pharmaceutique comprenant en tant que principe actif une combinaison de d-limoneme, de lupeol et du cinnamaldehyde et/ou de l'epicatechine et/ou du methylhydroxychalcone polymere et/ou d Download PDFInfo
- Publication number
- FR3061659B1 FR3061659B1 FR1771175A FR1771175A FR3061659B1 FR 3061659 B1 FR3061659 B1 FR 3061659B1 FR 1771175 A FR1771175 A FR 1771175A FR 1771175 A FR1771175 A FR 1771175A FR 3061659 B1 FR3061659 B1 FR 3061659B1
- Authority
- FR
- France
- Prior art keywords
- limoneme
- lupeol
- epicatechin
- cinnamaldehyde
- combination
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- PFTAWBLQPZVEMU-ZFWWWQNUSA-N (+)-epicatechin Natural products C1([C@@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-ZFWWWQNUSA-N 0.000 title 1
- PFTAWBLQPZVEMU-UKRRQHHQSA-N (-)-epicatechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-UKRRQHHQSA-N 0.000 title 1
- KJPRLNWUNMBNBZ-QPJJXVBHSA-N (E)-cinnamaldehyde Chemical compound O=C\C=C\C1=CC=CC=C1 KJPRLNWUNMBNBZ-QPJJXVBHSA-N 0.000 title 1
- QHMQAWNNHVPBQU-UHFFFAOYSA-N 3-(2-hydroxy-3-methylphenyl)-1-phenylprop-2-en-1-one Chemical compound CC1=CC=CC(C=CC(=O)C=2C=CC=CC=2)=C1O QHMQAWNNHVPBQU-UHFFFAOYSA-N 0.000 title 1
- 239000004480 active ingredient Substances 0.000 title 1
- 229940117916 cinnamic aldehyde Drugs 0.000 title 1
- KJPRLNWUNMBNBZ-UHFFFAOYSA-N cinnamic aldehyde Natural products O=CC=CC1=CC=CC=C1 KJPRLNWUNMBNBZ-UHFFFAOYSA-N 0.000 title 1
- LPTRNLNOHUVQMS-UHFFFAOYSA-N epicatechin Natural products Cc1cc(O)cc2OC(C(O)Cc12)c1ccc(O)c(O)c1 LPTRNLNOHUVQMS-UHFFFAOYSA-N 0.000 title 1
- 235000012734 epicatechin Nutrition 0.000 title 1
- MQYXUWHLBZFQQO-QGTGJCAVSA-N lupeol Chemical compound C1C[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C)CC[C@@H](C(=C)C)[C@@H]5[C@H]4CC[C@@H]3[C@]21C MQYXUWHLBZFQQO-QGTGJCAVSA-N 0.000 title 1
- PKGKOZOYXQMJNG-UHFFFAOYSA-N lupeol Natural products CC(=C)C1CC2C(C)(CCC3C4(C)CCC5C(C)(C)C(O)CCC5(C)C4CCC23C)C1 PKGKOZOYXQMJNG-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 229920000642 polymer Polymers 0.000 title 1
- 239000007788 liquid Substances 0.000 abstract 3
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- 230000003042 antagnostic effect Effects 0.000 abstract 1
- 230000006378 damage Effects 0.000 abstract 1
- 208000014674 injury Diseases 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/01—Hydrocarbons
- A61K31/015—Hydrocarbons carbocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/11—Aldehydes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Obesity (AREA)
- Neurology (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Communicable Diseases (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
Dispositif pour briser les pointes d’une ampoule contenant un liquide. L’invention concerne un dispositif permettant de briser sans risque de blessures les pointes d’une ampoule contenant un liquide pour permettre l’écoulement de ce liquide. Il est constitué d’un boîtier (1) présentant un orifice (2) dans lequel est introduite la pointe de l’ampoule (3). Un levier (4) est articulé en (6) sur le boîtier (1) et pourvu d’une saillie (5). Lorsque l’utilisateur exerce sur le levier (4) une force antagoniste à celle du ressort (7), la saillie (5) appuie sur la pointe de l’ampoule (3) pour la briser et la faire tomber dans le boîtier (1). Le dispositif selon l’invention est particulièrement destiné à l’ouverture des ampoules pharmaceutiques. Figure pour l’abrégé : Fig. 1
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP17825613.7A EP3565536A1 (fr) | 2017-01-07 | 2017-12-07 | Composition pharmaceutique utilisée pour traiter les troubles du syndrome métabolique, les maladies infectieuses, et leurs complications. |
PCT/IB2017/057731 WO2018127748A1 (fr) | 2017-01-07 | 2017-12-07 | Composition pharmaceutique utilisée pour traiter les troubles du syndrome métabolique, les maladies infectieuses, et leurs complications. |
CN201780082728.5A CN110139643A (zh) | 2017-01-07 | 2017-12-07 | 一种用于治疗代谢紊乱综合征、炎症及其并发症的药物成分 |
US16/481,853 US20200268770A1 (en) | 2017-01-07 | 2017-12-07 | Pharmaceutical composition used for treating metabolic syndrome disorders, infectious diseases, and complications thereof |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1770014A FR3061658A1 (fr) | 2017-01-07 | 2017-01-07 | Composition pharmaceutique comprenant en tant que principe actif une combinaison de d-limoneme, de lupeol et du cinnamaldehyde et/ou du methylhydroxychalcone polymere et/ou du beta-sitosterol et/ou de |
FR1770014 | 2017-01-07 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR3061659A1 FR3061659A1 (fr) | 2018-07-13 |
FR3061659B1 true FR3061659B1 (fr) | 2020-02-21 |
Family
ID=58632521
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR1770014A Withdrawn FR3061658A1 (fr) | 2017-01-07 | 2017-01-07 | Composition pharmaceutique comprenant en tant que principe actif une combinaison de d-limoneme, de lupeol et du cinnamaldehyde et/ou du methylhydroxychalcone polymere et/ou du beta-sitosterol et/ou de |
FR1771175A Active FR3061659B1 (fr) | 2017-01-07 | 2017-11-07 | Composition pharmaceutique comprenant en tant que principe actif une combinaison de d-limoneme, de lupeol et du cinnamaldehyde et/ou de l'epicatechine et/ou du methylhydroxychalcone polymere et/ou d |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR1770014A Withdrawn FR3061658A1 (fr) | 2017-01-07 | 2017-01-07 | Composition pharmaceutique comprenant en tant que principe actif une combinaison de d-limoneme, de lupeol et du cinnamaldehyde et/ou du methylhydroxychalcone polymere et/ou du beta-sitosterol et/ou de |
Country Status (5)
Country | Link |
---|---|
US (1) | US20200268770A1 (fr) |
EP (1) | EP3565536A1 (fr) |
CN (1) | CN110139643A (fr) |
FR (2) | FR3061658A1 (fr) |
WO (1) | WO2018127748A1 (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR3061658A1 (fr) * | 2017-01-07 | 2018-07-13 | Guy Faustin Monkam Nitcheu | Composition pharmaceutique comprenant en tant que principe actif une combinaison de d-limoneme, de lupeol et du cinnamaldehyde et/ou du methylhydroxychalcone polymere et/ou du beta-sitosterol et/ou de |
AU2018209164B2 (en) | 2017-01-17 | 2021-11-04 | Heparegenix Gmbh | Protein kinase inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death |
FR3100128B1 (fr) * | 2019-08-30 | 2022-02-18 | Nitcheu Guy Faustin Monkam | Composition pharmaceutique destinée à inhiber l’infectiosité du VIH, à traiter le syndrome d’immunodéficience acquise (SIDA) et ses complications |
CN111000849A (zh) * | 2019-12-19 | 2020-04-14 | 淮阴师范学院 | 羽扇豆醇dyc-6的应用和产品 |
CN111840262A (zh) * | 2020-07-15 | 2020-10-30 | 广东工业大学 | 肉桂醛衍生物在制备预防和/或治疗新型冠状病毒感染药物中的应用 |
FR3121038B1 (fr) * | 2021-03-27 | 2024-06-14 | Nitcheu Guy Faustin Monkam | Composition pharmaceutique destinée à inhiber l’infectiosité des virus à bicouche lipidique, à traiter les maladies associées et leurs complications. |
CN113648421A (zh) * | 2021-08-19 | 2021-11-16 | 中山大学中山眼科中心 | 磺酰脲类药物在制备治疗葡萄膜炎的药物中的应用 |
GB202113028D0 (en) * | 2021-09-13 | 2021-10-27 | Ucl Business Ltd | Sterol therapy |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6967030B2 (en) * | 2003-01-14 | 2005-11-22 | Wright Jonathan V | Formulation for insulin and glucose control |
US20070196520A1 (en) * | 2004-03-01 | 2007-08-23 | Fhg Corporation D/B/A Nutraceuticals | Methods and materials for reducing or eliminating risk factors associated with syndrome x |
WO2005113069A2 (fr) * | 2004-05-14 | 2005-12-01 | Research Development Foundation | Utilisation de curcumine et d'analogues de curcumine comme inhibiteurs de l'acc2 |
US20060286182A1 (en) * | 2005-06-21 | 2006-12-21 | Abeille Pharmaceuticals, Inc. | Synergistic cinnamon combinations and methods for enhancing insulin activity |
CN101028363A (zh) * | 2006-02-28 | 2007-09-05 | 舒刚 | 植物或草药及其挥发油提取物在制备治疗糖尿病药物中的新用途 |
CA2595096A1 (fr) * | 2007-07-27 | 2009-01-27 | Innovative Life Sciences Corporation | Produit a base d'herbes medicinales comprenant de la cannelle et du chocolat |
FR3061658A1 (fr) * | 2017-01-07 | 2018-07-13 | Guy Faustin Monkam Nitcheu | Composition pharmaceutique comprenant en tant que principe actif une combinaison de d-limoneme, de lupeol et du cinnamaldehyde et/ou du methylhydroxychalcone polymere et/ou du beta-sitosterol et/ou de |
-
2017
- 2017-01-07 FR FR1770014A patent/FR3061658A1/fr not_active Withdrawn
- 2017-11-07 FR FR1771175A patent/FR3061659B1/fr active Active
- 2017-12-07 EP EP17825613.7A patent/EP3565536A1/fr active Pending
- 2017-12-07 CN CN201780082728.5A patent/CN110139643A/zh active Pending
- 2017-12-07 WO PCT/IB2017/057731 patent/WO2018127748A1/fr unknown
- 2017-12-07 US US16/481,853 patent/US20200268770A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP3565536A1 (fr) | 2019-11-13 |
CN110139643A (zh) | 2019-08-16 |
FR3061658A1 (fr) | 2018-07-13 |
US20200268770A1 (en) | 2020-08-27 |
FR3061659A1 (fr) | 2018-07-13 |
WO2018127748A1 (fr) | 2018-07-12 |
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