FR3025802B1 - ANAEROBIC BIOREACTOR DEVICE WITH RETRACTABLE OBSERVATION MODULE - Google Patents

ANAEROBIC BIOREACTOR DEVICE WITH RETRACTABLE OBSERVATION MODULE Download PDF

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Publication number
FR3025802B1
FR3025802B1 FR1402077A FR1402077A FR3025802B1 FR 3025802 B1 FR3025802 B1 FR 3025802B1 FR 1402077 A FR1402077 A FR 1402077A FR 1402077 A FR1402077 A FR 1402077A FR 3025802 B1 FR3025802 B1 FR 3025802B1
Authority
FR
France
Prior art keywords
opening
bioreactor device
pressure
observation module
anaerobic bioreactor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1402077A
Other languages
French (fr)
Other versions
FR3025802A1 (en
Inventor
Mohamed Jebbar
Mickael Beauverger
Stephane L'haridon
Gregoire Michoud
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Univerdite de Bretagne Occidentale
Original Assignee
Centre National de la Recherche Scientifique CNRS
Univerdite de Bretagne Occidentale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, Univerdite de Bretagne Occidentale filed Critical Centre National de la Recherche Scientifique CNRS
Priority to FR1402077A priority Critical patent/FR3025802B1/en
Publication of FR3025802A1 publication Critical patent/FR3025802A1/en
Application granted granted Critical
Publication of FR3025802B1 publication Critical patent/FR3025802B1/en
Active legal-status Critical Current
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/22—Transparent or translucent parts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/40—Manifolds; Distribution pieces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/44—Multiple separable units; Modules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/18—External loop; Means for reintroduction of fermented biomass or liquid percolate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material

Abstract

L'invention concerne un dispositif bioréacteur (AB1) comprenant un conteneur principal (R1) adapté à une culture de micro-organismes soumis à une première pression (P1), le conteneur principal (R1) comprend une ouverture principale (MI1), une première ouverture secondaire (SI1) et une seconde ouverture secondaire (SI2), le bioréacteur (AB1) comprend, entre la première ouverture secondaire (SI1) et la seconde ouverture (SI2) une circuiterie (CIR1) comprenant une cellule d'observation (VC1) adaptée à la circulation d'un contenu sous une lentille (VCL) d'observation translucide, à une seconde pression (P2) sensiblement identique à la première pression (P1), et au moins deux éléments d'isolement (ISO1, ISO2) adaptés une séparation mécanique de la cellule d'observation (VC1).The invention relates to a bioreactor device (AB1) comprising a main container (R1) adapted to a culture of microorganisms subjected to a first pressure (P1), the main container (R1) comprises a main opening (MI1), a first secondary opening (SI1) and a second secondary opening (SI2), the bioreactor (AB1) comprises, between the first secondary opening (SI1) and the second opening (SI2) a circuit (CIR1) comprising an observation cell (VC1) adapted to the circulation of content under a translucent observation lens (VCL), at a second pressure (P2) substantially identical to the first pressure (P1), and at least two isolation elements (ISO1, ISO2) adapted mechanical separation of the observation cell (VC1).

FR1402077A 2014-09-16 2014-09-16 ANAEROBIC BIOREACTOR DEVICE WITH RETRACTABLE OBSERVATION MODULE Active FR3025802B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR1402077A FR3025802B1 (en) 2014-09-16 2014-09-16 ANAEROBIC BIOREACTOR DEVICE WITH RETRACTABLE OBSERVATION MODULE

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1402077 2014-09-16
FR1402077A FR3025802B1 (en) 2014-09-16 2014-09-16 ANAEROBIC BIOREACTOR DEVICE WITH RETRACTABLE OBSERVATION MODULE

Publications (2)

Publication Number Publication Date
FR3025802A1 FR3025802A1 (en) 2016-03-18
FR3025802B1 true FR3025802B1 (en) 2019-12-27

Family

ID=52450163

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1402077A Active FR3025802B1 (en) 2014-09-16 2014-09-16 ANAEROBIC BIOREACTOR DEVICE WITH RETRACTABLE OBSERVATION MODULE

Country Status (1)

Country Link
FR (1) FR3025802B1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3819368B1 (en) * 2019-11-08 2022-03-30 Ceidos SA Cell culture monitoring system

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6874355B2 (en) * 2001-03-08 2005-04-05 Abb Ab Method and device for monitoring and controlling a process
US8293524B2 (en) * 2006-03-31 2012-10-23 Fluxion Biosciences Inc. Methods and apparatus for the manipulation of particle suspensions and testing thereof
CN101624567B (en) * 2009-08-13 2012-02-15 浙江大学 Microorganism online observation device
CN201495225U (en) * 2009-08-13 2010-06-02 浙江大学 Online microbe observation device

Also Published As

Publication number Publication date
FR3025802A1 (en) 2016-03-18

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