FR3005863B1 - Procede de prepartion d’une emulsion d’un principe actif et particules obtenues a partir de cette emulsion - Google Patents

Procede de prepartion d’une emulsion d’un principe actif et particules obtenues a partir de cette emulsion

Info

Publication number
FR3005863B1
FR3005863B1 FR1354539A FR1354539A FR3005863B1 FR 3005863 B1 FR3005863 B1 FR 3005863B1 FR 1354539 A FR1354539 A FR 1354539A FR 1354539 A FR1354539 A FR 1354539A FR 3005863 B1 FR3005863 B1 FR 3005863B1
Authority
FR
France
Prior art keywords
emulsion
preparing
active ingredient
particles obtained
obtained therefrom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR1354539A
Other languages
English (en)
Other versions
FR3005863A1 (fr
Inventor
Jean Marie Dollat
Geraldine Lafitte
Emilie Ruffin
Odile Chambin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Adisseo France SAS
Original Assignee
Adisseo France SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adisseo France SAS filed Critical Adisseo France SAS
Priority to FR1354539A priority Critical patent/FR3005863B1/fr
Priority to PCT/FR2014/051190 priority patent/WO2014188124A1/fr
Priority to EP14731697.0A priority patent/EP2999351A1/fr
Priority to CN201480029195.0A priority patent/CN105283083A/zh
Priority to JP2016514463A priority patent/JP2016527185A/ja
Priority to US14/893,051 priority patent/US20160101064A1/en
Publication of FR3005863A1 publication Critical patent/FR3005863A1/fr
Application granted granted Critical
Publication of FR3005863B1 publication Critical patent/FR3005863B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
    • A23J1/20—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00—Working-up of proteins for foodstuffs
    • A23J3/04—Animal proteins
    • A23J3/08—Dairy proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A61K8/066—Multiple emulsions, e.g. water-in-oil-in-water
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/678—Tocopherol, i.e. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/733—Alginic acid; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/10—General cosmetic use

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fodder In General (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR1354539A 2013-05-21 2013-05-21 Procede de prepartion d’une emulsion d’un principe actif et particules obtenues a partir de cette emulsion Expired - Fee Related FR3005863B1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR1354539A FR3005863B1 (fr) 2013-05-21 2013-05-21 Procede de prepartion d’une emulsion d’un principe actif et particules obtenues a partir de cette emulsion
PCT/FR2014/051190 WO2014188124A1 (fr) 2013-05-21 2014-05-21 Procede de preparation d'une emulsion d'un principe actif et particules obtenues a partir de cette emulsion
EP14731697.0A EP2999351A1 (fr) 2013-05-21 2014-05-21 Procede de preparation d'une emulsion d'un principe actif et particules obtenues a partir de cette emulsion
CN201480029195.0A CN105283083A (zh) 2013-05-21 2014-05-21 制造活性成分乳液的方法和从该乳液中获得的颗粒
JP2016514463A JP2016527185A (ja) 2013-05-21 2014-05-21 活性成分のエマルジョンを調製する方法及び当該エマルジョンから得られる粒子
US14/893,051 US20160101064A1 (en) 2013-05-21 2014-05-21 Process for preparing an emulsion of an active ingredient and particles obtained from this emulsion

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1354539A FR3005863B1 (fr) 2013-05-21 2013-05-21 Procede de prepartion d’une emulsion d’un principe actif et particules obtenues a partir de cette emulsion

Publications (2)

Publication Number Publication Date
FR3005863A1 FR3005863A1 (fr) 2014-11-28
FR3005863B1 true FR3005863B1 (fr) 2015-08-21

Family

ID=48795786

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1354539A Expired - Fee Related FR3005863B1 (fr) 2013-05-21 2013-05-21 Procede de prepartion d’une emulsion d’un principe actif et particules obtenues a partir de cette emulsion

Country Status (6)

Country Link
US (1) US20160101064A1 (fr)
EP (1) EP2999351A1 (fr)
JP (1) JP2016527185A (fr)
CN (1) CN105283083A (fr)
FR (1) FR3005863B1 (fr)
WO (1) WO2014188124A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108186381B (zh) * 2017-12-26 2019-09-06 浙江大学 一种在化妆品中激发锌活性离子的方法
CN108324583B (zh) * 2017-12-26 2019-10-18 浙江大学 一种在化妆品中激发金属活性离子的方法
CN112315913A (zh) * 2019-07-19 2021-02-05 中国农业大学 一种硒纳米双乳化微制剂的制备方法
CN110448482B (zh) * 2019-09-27 2020-06-09 瑞希(重庆)生物科技有限公司 一种乳剂及其制备方法
FR3102991B1 (fr) * 2019-11-07 2021-11-26 Huddle Corp Procédé de fabrication d’un aliment ou complément alimentaire pour animaux d’élevage
CN111631385A (zh) * 2020-06-17 2020-09-08 武汉轻工大学 一种荷载姜黄素Pickering乳液及其制备方法
CN112056544B (zh) * 2020-09-21 2022-07-29 华中农业大学 一种可稳定负载脂溶性活性成分的果胶乳液凝胶的制备方法
CN115336760B (zh) * 2022-08-16 2024-04-30 河南科技学院 一种基于交叉水凝胶构建的超稳定混合型高内相乳液体系及其制备方法
CN116369499B (zh) * 2023-05-18 2024-04-05 东北农业大学 一种低油相Pickering乳液凝胶的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5985177A (en) * 1995-12-14 1999-11-16 Shiseido Co., Ltd. O/W/O type multiple emulsion and method of preparing the same
JP3881699B2 (ja) * 1996-10-09 2007-02-14 ジボーダン―ルール（アンテルナシヨナル）ソシエテ アノニム 食品添加剤としてのビーズの製造方法
CA2384885C (fr) * 1999-12-23 2008-04-01 Aventis Animal Nutrition S.A. Composition vitaminique particulaire
AU2004229176A1 (en) * 2003-04-15 2004-10-28 Campina B.V. Method for producing a whey protein concentrate enriched in beta-lactoglobulin and texture enhancer based thereupon for use in dairy products
EP2059130A2 (fr) * 2006-08-17 2009-05-20 University of Massachusetts Émulsions stabilisées, procédés d'élaboration, et produits alimentaires correspondants à teneur réduite en matières grasses
EP2124905B1 (fr) * 2007-01-10 2016-09-07 DSM Nutritional Products AG Microcapsules comprenant de la proteine de pois
AU2008330337A1 (en) * 2007-11-29 2009-06-04 Nizo Food Research B.V. Protein-based oil - encapsulates
EP2238843A1 (fr) * 2009-02-26 2010-10-13 DSM IP Assets B.V. Compositions d'ingrédients actifs liposolubles contenant des conjugués de protéine-polysaccharide
FR2953409B1 (fr) * 2009-12-09 2011-12-23 Adisseo France Sas Particules de principes actifs liposolubles stables
CN102416024B (zh) * 2011-12-08 2012-11-21 大连理工大学 一种噬菌体口服微球制剂及其制备方法
US20130202740A1 (en) * 2012-02-08 2013-08-08 Pepsico, Inc. Acidic Aqueous Product Comprising Oil-Containing Microcapsules and Method for the Manufacture Thereof

Also Published As

Publication number Publication date
WO2014188124A1 (fr) 2014-11-27
EP2999351A1 (fr) 2016-03-30
JP2016527185A (ja) 2016-09-08
US20160101064A1 (en) 2016-04-14
CN105283083A (zh) 2016-01-27
FR3005863A1 (fr) 2014-11-28

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