FR2909092B1 - Nouveaux anticorps anti-proliferation - Google Patents

Nouveaux anticorps anti-proliferation

Info

Publication number
FR2909092B1
FR2909092B1 FR0610329A FR0610329A FR2909092B1 FR 2909092 B1 FR2909092 B1 FR 2909092B1 FR 0610329 A FR0610329 A FR 0610329A FR 0610329 A FR0610329 A FR 0610329A FR 2909092 B1 FR2909092 B1 FR 2909092B1
Authority
FR
France
Prior art keywords
new anti
proliferation
antibodies
proliferation antibodies
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0610329A
Other languages
English (en)
French (fr)
Other versions
FR2909092A1 (fr
Inventor
Liliane Goetsch
Nathalie Corvaia
Jean Francois Haeuw
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Original Assignee
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0610329A priority Critical patent/FR2909092B1/fr
Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Priority to UAA200906473A priority patent/UA99602C2/ru
Priority to CA002670039A priority patent/CA2670039A1/en
Priority to KR1020097009675A priority patent/KR20090088878A/ko
Priority to BRPI0719323-8A priority patent/BRPI0719323A2/pt
Priority to CN2007800405398A priority patent/CN101535344B/zh
Priority to EP07847306A priority patent/EP2074148A1/en
Priority to GEAP200711322A priority patent/GEP20125629B/en
Priority to CL200703357A priority patent/CL2007003357A1/es
Priority to PCT/EP2007/062760 priority patent/WO2008062063A1/en
Priority to MX2009005293A priority patent/MX2009005293A/es
Priority to NZ576174A priority patent/NZ576174A/en
Priority to HK10100290.5A priority patent/HK1132752B/xx
Priority to RU2009123409/10A priority patent/RU2451689C2/ru
Priority to JP2009537651A priority patent/JP2010509931A/ja
Priority to AU2007324509A priority patent/AU2007324509B2/en
Priority to SA07280637A priority patent/SA07280637B1/ar
Priority to TW096144763A priority patent/TW200829602A/zh
Priority to US12/125,726 priority patent/US8071730B2/en
Publication of FR2909092A1 publication Critical patent/FR2909092A1/fr
Priority to NI200900079A priority patent/NI200900079A/es
Priority to CR10788A priority patent/CR10788A/es
Priority to IL198744A priority patent/IL198744A0/en
Priority to GT200900126A priority patent/GT200900126A/es
Priority to MA31875A priority patent/MA30891B1/fr
Priority to CU20090082A priority patent/CU23792A3/es
Priority to TNP2009000194A priority patent/TN2009000194A1/fr
Priority to EC2009009341A priority patent/ECSP099341A/es
Priority to NO20092360A priority patent/NO20092360L/no
Priority to US13/310,840 priority patent/US20120156191A1/en
Application granted granted Critical
Publication of FR2909092B1 publication Critical patent/FR2909092B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/54—F(ab')2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
FR0610329A 2006-11-24 2006-11-24 Nouveaux anticorps anti-proliferation Expired - Fee Related FR2909092B1 (fr)

Priority Applications (29)

Application Number Priority Date Filing Date Title
FR0610329A FR2909092B1 (fr) 2006-11-24 2006-11-24 Nouveaux anticorps anti-proliferation
CL200703357A CL2007003357A1 (es) 2006-11-24 2007-11-23 Anticuerpo o fragmento funcional del mismo capaz de inhibir la proliferacion de celulas tumorales in vitro y/o in vivo; acido nucleico que lo codifica; metodo de produccion; composicion que lo comprende; y su uso para tratar el cancer.
KR1020097009675A KR20090088878A (ko) 2006-11-24 2007-11-23 신규한 항증식 항체
BRPI0719323-8A BRPI0719323A2 (pt) 2006-11-24 2007-11-23 Anticorpos antiproliferação
CN2007800405398A CN101535344B (zh) 2006-11-24 2007-11-23 新型抗增殖抗体
EP07847306A EP2074148A1 (en) 2006-11-24 2007-11-23 Novel antiproliferation antibodies
GEAP200711322A GEP20125629B (en) 2006-11-24 2007-11-23 Novel antiproliferation antibodies
CA002670039A CA2670039A1 (en) 2006-11-24 2007-11-23 Novel antiproliferation antibodies
PCT/EP2007/062760 WO2008062063A1 (en) 2006-11-24 2007-11-23 Novel antiproliferation antibodies
MX2009005293A MX2009005293A (es) 2006-11-24 2007-11-23 Novedosos anticuerpos antiproliferacion.
NZ576174A NZ576174A (en) 2006-11-24 2007-11-23 Novel antiproliferation antibodies
HK10100290.5A HK1132752B (en) 2006-11-24 2007-11-23 Novel antiproliferation antibodies
RU2009123409/10A RU2451689C2 (ru) 2006-11-24 2007-11-23 Новые антипролиферативные антитела
JP2009537651A JP2010509931A (ja) 2006-11-24 2007-11-23 新規抗増殖性化合物
UAA200906473A UA99602C2 (ru) 2006-11-24 2007-11-23 Антитело, специфически связывающееся с jam-a, способное ингибировать пролиферацию опухолевых клеток
AU2007324509A AU2007324509B2 (en) 2006-11-24 2007-11-23 Novel antiproliferation antibodies
SA07280637A SA07280637B1 (ar) 2006-11-24 2007-11-24 مضادات أجسام مضادة للانقسام جديدة
TW096144763A TW200829602A (en) 2006-11-24 2007-11-26 Novel antiproliferation antibodies
US12/125,726 US8071730B2 (en) 2006-11-24 2008-05-22 Anti-JAM-A antibodies
NI200900079A NI200900079A (es) 2006-11-24 2009-05-06 Novedosos anticuerpos antiproliferación.
CR10788A CR10788A (es) 2006-11-24 2009-05-08 Nuevos anticuerpos antiproliferativos
IL198744A IL198744A0 (en) 2006-11-24 2009-05-14 Novel antiproliferation antibodies
GT200900126A GT200900126A (es) 2006-11-24 2009-05-14 Novedosos anticuerpos antiproliferacion
MA31875A MA30891B1 (fr) 2006-11-24 2009-05-14 Nouveaux anticorps anti-proliferation
CU20090082A CU23792A3 (es) 2006-11-24 2009-05-14 Novedosos anticuerpos antiproliferación
TNP2009000194A TN2009000194A1 (en) 2006-11-24 2009-05-18 Novel antiproliferation antibodies
EC2009009341A ECSP099341A (es) 2006-11-24 2009-05-18 Nuevos anticuerpos antiproliferativos
NO20092360A NO20092360L (no) 2006-11-24 2009-06-19 Nye antiproliferasjonsantistoffer
US13/310,840 US20120156191A1 (en) 2006-11-24 2011-12-05 Anti-jam-a antibodies

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0610329A FR2909092B1 (fr) 2006-11-24 2006-11-24 Nouveaux anticorps anti-proliferation

Publications (2)

Publication Number Publication Date
FR2909092A1 FR2909092A1 (fr) 2008-05-30
FR2909092B1 true FR2909092B1 (fr) 2012-10-19

Family

ID=37903981

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0610329A Expired - Fee Related FR2909092B1 (fr) 2006-11-24 2006-11-24 Nouveaux anticorps anti-proliferation

Country Status (27)

Country Link
US (2) US8071730B2 (enExample)
EP (1) EP2074148A1 (enExample)
JP (1) JP2010509931A (enExample)
KR (1) KR20090088878A (enExample)
CN (1) CN101535344B (enExample)
AU (1) AU2007324509B2 (enExample)
BR (1) BRPI0719323A2 (enExample)
CA (1) CA2670039A1 (enExample)
CL (1) CL2007003357A1 (enExample)
CR (1) CR10788A (enExample)
CU (1) CU23792A3 (enExample)
EC (1) ECSP099341A (enExample)
FR (1) FR2909092B1 (enExample)
GE (1) GEP20125629B (enExample)
GT (1) GT200900126A (enExample)
IL (1) IL198744A0 (enExample)
MA (1) MA30891B1 (enExample)
MX (1) MX2009005293A (enExample)
NI (1) NI200900079A (enExample)
NO (1) NO20092360L (enExample)
NZ (1) NZ576174A (enExample)
RU (1) RU2451689C2 (enExample)
SA (1) SA07280637B1 (enExample)
TN (1) TN2009000194A1 (enExample)
TW (1) TW200829602A (enExample)
UA (1) UA99602C2 (enExample)
WO (1) WO2008062063A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JOP20080381B1 (ar) 2007-08-23 2023-03-28 Amgen Inc بروتينات مرتبطة بمولدات مضادات تتفاعل مع بروبروتين كونفيرتاز سيتيليزين ككسين من النوع 9 (pcsk9)
WO2010002862A2 (en) * 2008-07-01 2010-01-07 Aveo Pharmaceuticals, Inc. Fibroblast growth factor receptor 3 (fgfr3) binding proteins
CA2777698A1 (en) * 2009-10-30 2011-05-05 Merck Sharp & Dohme Corp. Ax1 and ax189 pcsk9 antagonists and variants
CA2815277A1 (en) * 2010-10-29 2012-05-03 Immunogen, Inc. Novel egfr-binding molecules and immunoconjugates thereof
EP2455403A1 (en) 2010-11-23 2012-05-23 Pierre Fabre Medicament Homogeneous humanized antibodies against JAM-A that inhibit proliferation
JOP20200043A1 (ar) 2011-05-10 2017-06-16 Amgen Inc طرق معالجة أو منع الاضطرابات المختصة بالكوليسترول
US20130287790A1 (en) * 2012-03-30 2013-10-31 The Board Of Trustees Of The Leland Standford Junior University Use of jam-a in diagnosing and treating leukemia
EA039663B1 (ru) 2012-05-03 2022-02-24 Амген Инк. Применение антитела против pcsk9 для снижения сывороточного холестерина лпнп и лечения связанных с холестерином расстройств
PL3489261T3 (pl) 2012-08-24 2021-08-16 The Regents Of The University Of California Przeciwciała i szczepionki do stosowania w leczeniu nowotworów z ekspresją ROR1 i w hamowaniu przerzutu
KR20150097304A (ko) 2014-02-18 2015-08-26 삼성전자주식회사 항 EGFR DARPin을 포함하는 EGFR/HER2 이중 특이 항체
RU2756275C2 (ru) 2016-03-01 2021-09-29 Юссум Рисёрч Девелопмент Компани Оф Зэ Хибру Юниверсити Оф Иерусалим Лтд. Антитела, специфические к рецептору полиовируса (pvr) человека
KR20230047507A (ko) 2016-06-27 2023-04-07 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 암 치료 조합
CA3032826A1 (en) * 2016-08-03 2018-02-08 Nextcure, Inc. Compositions and methods for modulating lair signal transduction
CN109022366A (zh) * 2018-08-16 2018-12-18 江南大学 一株分泌抗左旋咪唑单克隆抗体的杂交瘤细胞株及其应用
KR20220082007A (ko) 2019-10-08 2022-06-16 넥틴 테라퓨틱스 리미티드 폴리오바이러스 수용체(pvr)에 대한 항체 및 이의 용도
CN114740108B (zh) * 2022-03-28 2023-07-14 天津键凯科技有限公司 一种聚合物修饰抗体类药物的修饰度的测定方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9604470D0 (sv) * 1996-12-04 1996-12-04 Tamas Bartfai Konsulting Ab Transmembrane component of tight junction
US6235883B1 (en) * 1997-05-05 2001-05-22 Abgenix, Inc. Human monoclonal antibodies to epidermal growth factor receptor
US20030171568A1 (en) * 1998-09-16 2003-09-11 Avi Ashkenazi Use of A33 antigens and JAM-IT
SK14812000A3 (sk) * 1998-04-03 2001-08-06 Chugai Seiyaku Kabushiki Kaisha Chimérny reťazec protilátky, chimérna protilátka, v oblasť, humanizovaný reťazec protilátky, humanizovaná protilátka, dna, expresný vektor, hostiteľ, spôsob prípravy a liečivo
MXPA01009110A (es) * 1999-03-11 2002-08-20 Rmf Dictagene Sa Moleculas de adhesion vascular y modulacion de su funcion.
EP1708961B1 (en) * 2003-12-04 2011-03-09 Abbott Biotherapeutics Corp. Anti-ip-10 antibodies
WO2006008076A2 (en) * 2004-07-16 2006-01-26 Universita Degli Studi Di Milano Methods and agents stimulating the immune response
WO2006121207A1 (en) * 2005-05-12 2006-11-16 Oncotherapy Science, Inc. Methods for damaging cells using effector function of anti-dsc2 antibody
EP2021371A2 (en) * 2006-04-28 2009-02-11 Oregon Health and Science University Monoclonal antibodies specific for pancreatic endocrine, exocrine or ductal cells

Also Published As

Publication number Publication date
NI200900079A (es) 2010-11-10
CA2670039A1 (en) 2008-05-29
AU2007324509B2 (en) 2013-01-17
TN2009000194A1 (en) 2010-10-18
SA07280637B1 (ar) 2012-04-11
KR20090088878A (ko) 2009-08-20
HK1132752A1 (en) 2010-03-05
CL2007003357A1 (es) 2008-04-04
CN101535344B (zh) 2013-10-16
MX2009005293A (es) 2009-08-07
AU2007324509A1 (en) 2008-05-29
GT200900126A (es) 2011-09-02
JP2010509931A (ja) 2010-04-02
GEP20125629B (en) 2012-09-10
RU2009123409A (ru) 2010-12-27
TW200829602A (en) 2008-07-16
US20100092455A1 (en) 2010-04-15
RU2451689C2 (ru) 2012-05-27
CR10788A (es) 2009-06-23
US8071730B2 (en) 2011-12-06
CU23792A3 (es) 2012-03-15
WO2008062063A1 (en) 2008-05-29
FR2909092A1 (fr) 2008-05-30
ECSP099341A (es) 2009-06-30
EP2074148A1 (en) 2009-07-01
MA30891B1 (fr) 2009-11-02
UA99602C2 (ru) 2012-09-10
CN101535344A (zh) 2009-09-16
NZ576174A (en) 2012-03-30
NO20092360L (no) 2009-08-11
US20120156191A1 (en) 2012-06-21
BRPI0719323A2 (pt) 2014-02-04
IL198744A0 (en) 2010-02-17

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Effective date: 20160729