FR2904311B1 - Nouveau procede de synthese de derives (e) stilbeniques perm permettant d'obtenir le resveratrol et le piceatannol - Google Patents

Nouveau procede de synthese de derives (e) stilbeniques perm permettant d'obtenir le resveratrol et le piceatannol

Info

Publication number
FR2904311B1
FR2904311B1 FR0653178A FR0653178A FR2904311B1 FR 2904311 B1 FR2904311 B1 FR 2904311B1 FR 0653178 A FR0653178 A FR 0653178A FR 0653178 A FR0653178 A FR 0653178A FR 2904311 B1 FR2904311 B1 FR 2904311B1
Authority
FR
France
Prior art keywords
stilbenic
piceatannol
perm
synthesis
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0653178A
Other languages
English (en)
Other versions
FR2904311A1 (fr
Inventor
Alain Schouteeten
Sebastien Jus
Jean Claude Vallejos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Weylchem Lamotte SAS
Original Assignee
Clariant Speciality Fine Chemicals France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0653178A priority Critical patent/FR2904311B1/fr
Application filed by Clariant Speciality Fine Chemicals France filed Critical Clariant Speciality Fine Chemicals France
Priority to ES09015839T priority patent/ES2436034T3/es
Priority to EP09015839.5A priority patent/EP2202215B8/fr
Priority to RU2009107169/04A priority patent/RU2443671C2/ru
Priority to EP07787880.9A priority patent/EP2049459B8/fr
Priority to CA2658652A priority patent/CA2658652C/fr
Priority to JP2009521253A priority patent/JP5254974B2/ja
Priority to PCT/EP2007/057650 priority patent/WO2008012321A1/fr
Priority to US12/375,507 priority patent/US8101804B2/en
Priority to CN200780027871.0A priority patent/CN101495436B/zh
Priority to ES07787880T priority patent/ES2436110T3/es
Publication of FR2904311A1 publication Critical patent/FR2904311A1/fr
Application granted granted Critical
Publication of FR2904311B1 publication Critical patent/FR2904311B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/48—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups having nitrogen atoms of sulfonamide groups further bound to another hetero atom
    • C07C311/49—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups having nitrogen atoms of sulfonamide groups further bound to another hetero atom to nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/01—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis
    • C07C37/055—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis the substituted group being bound to oxygen, e.g. ether group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/26—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C07C45/676—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton by elimination of carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
FR0653178A 2006-07-28 2006-07-28 Nouveau procede de synthese de derives (e) stilbeniques perm permettant d'obtenir le resveratrol et le piceatannol Expired - Fee Related FR2904311B1 (fr)

Priority Applications (11)

Application Number Priority Date Filing Date Title
FR0653178A FR2904311B1 (fr) 2006-07-28 2006-07-28 Nouveau procede de synthese de derives (e) stilbeniques perm permettant d'obtenir le resveratrol et le piceatannol
US12/375,507 US8101804B2 (en) 2006-07-28 2007-07-25 Process for the synthesis of (E)-stilbene derivatives which makes it possible to obtain resveratrol and piceatannol
RU2009107169/04A RU2443671C2 (ru) 2006-07-28 2007-07-25 Новый способ синтеза (е)-стильбеновых производных, который позволяет получить ресвератрол и писатаннол
EP07787880.9A EP2049459B8 (fr) 2006-07-28 2007-07-25 Nouveau procede de synthese de derives (e)-stilbene permettant d'obtenir du resveratrol et du piceatannol
CA2658652A CA2658652C (fr) 2006-07-28 2007-07-25 Nouveau procede de synthese de derives (e)-stilbene permettant d'obtenir du resveratrol et du piceatannol
JP2009521253A JP5254974B2 (ja) 2006-07-28 2007-07-25 レスベラトロールおよびピセアタンノールを得ることを可能にする（ｅ）−スチルベン誘導体を合成するための新規な方法
ES09015839T ES2436034T3 (es) 2006-07-28 2007-07-25 Nuevo proceso para la síntesis de derivados de (E)-estilbeno que hace posible obtener resveratrol y piceatannol
EP09015839.5A EP2202215B8 (fr) 2006-07-28 2007-07-25 Nouveau procédé pour la synthèse des dérivés de (E)-stilbène qui permet d'obtenir du resvératrol et piceatannol
CN200780027871.0A CN101495436B (zh) 2006-07-28 2007-07-25 可以得到白藜芦醇和四羟反式茋的合成(e)-茋衍生物的方法
ES07787880T ES2436110T3 (es) 2006-07-28 2007-07-25 Nuevo proceso para la síntesis de derivados de (E)-estilbeno que hace posible obtener resveratrol y piceatannol
PCT/EP2007/057650 WO2008012321A1 (fr) 2006-07-28 2007-07-25 Nouveau procédé de synthèse de dérivés (e)-stilbène permettant d'obtenir du resvératrol et du picéatannol

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0653178A FR2904311B1 (fr) 2006-07-28 2006-07-28 Nouveau procede de synthese de derives (e) stilbeniques perm permettant d'obtenir le resveratrol et le piceatannol

Publications (2)

Publication Number Publication Date
FR2904311A1 FR2904311A1 (fr) 2008-02-01
FR2904311B1 true FR2904311B1 (fr) 2013-01-11

Family

ID=37864505

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0653178A Expired - Fee Related FR2904311B1 (fr) 2006-07-28 2006-07-28 Nouveau procede de synthese de derives (e) stilbeniques perm permettant d'obtenir le resveratrol et le piceatannol

Country Status (9)

Country Link
US (1) US8101804B2 (fr)
EP (2) EP2049459B8 (fr)
JP (1) JP5254974B2 (fr)
CN (1) CN101495436B (fr)
CA (1) CA2658652C (fr)
ES (2) ES2436034T3 (fr)
FR (1) FR2904311B1 (fr)
RU (1) RU2443671C2 (fr)
WO (1) WO2008012321A1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2921921B1 (fr) * 2007-10-03 2011-08-19 Clariant Specialty Fine Chem F Procede de synthese de composes polyhydroxystilbeniques.
CN101139267B (zh) * 2007-10-09 2014-01-29 沈阳药科大学 白藜芦醇衍生物、类似物及其制备方法和用途
CN101284755B (zh) * 2008-05-19 2011-07-27 浙江工业大学 共轭烯烃类化合物的化学合成方法
KR101048475B1 (ko) 2008-12-03 2011-07-11 전남대학교산학협력단 박테리아 사이토크롬 피450을 이용한 피세아타놀의 신규한 생산방법 및 이를 위한 조성물
AU2012275841A1 (en) 2011-06-27 2014-01-16 The Jackson Laboratory Methods and compositions for treatment of cancer and autoimmune disease
CN105030750B (zh) * 2011-12-23 2018-08-28 中国医学科学院医药生物技术研究所 一组木豆素结构类似化合物在抗丙肝病毒和抗艾滋病毒的应用
US9701621B2 (en) 2013-02-13 2017-07-11 Indiana University Research & Technology Corporation Poly-cyanostilbene macrocycles
US10077233B2 (en) 2013-02-13 2018-09-18 Indiana University Research And Technology Corporation Poly-cyanostilbene macrocycles
WO2014127171A1 (fr) * 2013-02-13 2014-08-21 Indiana University Research And Technology Corporation Macrocycles de poly-cyanostilbène
US8921614B1 (en) * 2013-02-26 2014-12-30 The United States Of America As Represented By The Secretary Of The Navy Selective deoxygenation of hydroxybenzaldehydes
CN103992290B (zh) * 2013-05-14 2016-07-06 中国医学科学院医药生物技术研究所 二芳基乙烯结构类似化合物及其制备方法和应用
FR3029912B1 (fr) * 2014-12-12 2018-03-09 L'oreal Nouveaux derives de resveratrol pour lutter contre le vieillissement cutane, compositions et utilisation en cosmetique
TW201702218A (zh) 2014-12-12 2017-01-16 美國杰克森實驗室 關於治療癌症、自體免疫疾病及神經退化性疾病之組合物及方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2537950A (en) * 1948-11-05 1951-01-16 Milton J Allen Preparation of substituted diamino-stilbenes from pinacols
US3767289A (en) * 1970-12-31 1973-10-23 Ibm Class of stable trans-stilbene compounds, some displaying nematic mesophases at or near room temperature and others in a range up to 100{20 {11 c
JP3330155B2 (ja) * 1991-02-22 2002-09-30 石原産業株式会社 ヒドラゾン系化合物、それらの製造方法及びそれらの製造用中間体ならびにそれらを含有する有害生物防除剤
AU5650299A (en) * 1998-09-11 2000-04-03 Ajinomoto Co., Inc. Benzene derivatives and medicinal use thereof
FR2789577B1 (fr) * 1999-02-17 2002-04-05 Oreal Utilisation de derives substitues en 3 du stilbene comme actifs deodorants dans les compositions cosmetiques
WO2000069430A1 (fr) 1999-05-18 2000-11-23 Calyx Therapeutics, Inc. Composes diphenylethylene innovants
AU2001241539A1 (en) * 2000-02-16 2001-08-27 Brigham Young University Synthesis of resveratrol
WO2003086414A1 (fr) * 2002-04-10 2003-10-23 Arizona Board Of Regents Modification structurelle du resveratrol: phosphate de resverastatine de sodium
EP1466884A1 (fr) 2003-04-08 2004-10-13 Sochinaz SA Procédé de préparation du resvératrol et ses applications
CN100348564C (zh) * 2003-09-05 2007-11-14 帝斯曼知识产权资产管理有限公司 二苯乙烯衍生物的制备方法
EP1753708B1 (fr) 2004-01-20 2018-02-21 Brigham Young University Noveaux composes activant sirtuine et leurs methodes de preparation
EP1884508A1 (fr) 2006-07-28 2008-02-06 Portela & Ca., S.A. Procédé de préparation de stilbènes polyhydroxylés par condensation de claisen
WO2008012108A2 (fr) * 2006-07-28 2008-01-31 Portela & Ca., S.A. Préparation de stilbènes polyhydroxylés

Also Published As

Publication number Publication date
EP2202215B8 (fr) 2013-11-13
US20100004483A1 (en) 2010-01-07
CA2658652C (fr) 2014-10-28
RU2443671C2 (ru) 2012-02-27
WO2008012321A1 (fr) 2008-01-31
JP5254974B2 (ja) 2013-08-07
RU2009107169A (ru) 2010-09-10
EP2202215B1 (fr) 2013-10-02
ES2436034T3 (es) 2013-12-26
FR2904311A1 (fr) 2008-02-01
JP2009544663A (ja) 2009-12-17
CN101495436B (zh) 2014-02-26
EP2049459B8 (fr) 2013-11-13
ES2436110T3 (es) 2013-12-27
CA2658652A1 (fr) 2008-01-31
EP2202215A3 (fr) 2010-09-08
US8101804B2 (en) 2012-01-24
EP2049459A1 (fr) 2009-04-22
EP2202215A2 (fr) 2010-06-30
EP2049459B1 (fr) 2013-10-02
CN101495436A (zh) 2009-07-29

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Legal Events

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CA Change of address

Effective date: 20130830

ST Notification of lapse

Effective date: 20150331

CD Change of name or company name

Owner name: WEYLCHEM LAMOTTE, FR

Effective date: 20151013