FR2898357B1 - Derives d'amidine et leurs applications a titre de medicament - Google Patents

Derives d'amidine et leurs applications a titre de medicament

Info

Publication number
FR2898357B1
FR2898357B1 FR0601999A FR0601999A FR2898357B1 FR 2898357 B1 FR2898357 B1 FR 2898357B1 FR 0601999 A FR0601999 A FR 0601999A FR 0601999 A FR0601999 A FR 0601999A FR 2898357 B1 FR2898357 B1 FR 2898357B1
Authority
FR
France
Prior art keywords
applications
medicinal product
amidine derivatives
amidine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR0601999A
Other languages
English (en)
Other versions
FR2898357A1 (fr
Inventor
Serge Auvin
Dennis Bigg
De Lassauniere Pierre Etienne Chabrier
Bernadette Pignol
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0601999A priority Critical patent/FR2898357B1/fr
Application filed by Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS filed Critical Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Priority to CN2006800388504A priority patent/CN101291676B/zh
Priority to JP2008536083A priority patent/JP5280850B2/ja
Priority to US12/090,991 priority patent/US7659266B2/en
Priority to PT06820232T priority patent/PT1954288E/pt
Priority to DK06820232.4T priority patent/DK1954288T3/da
Priority to CA002626591A priority patent/CA2626591A1/fr
Priority to PL06820232T priority patent/PL1954288T3/pl
Priority to EP06820232A priority patent/EP1954288B1/fr
Priority to PCT/FR2006/002338 priority patent/WO2007045761A1/fr
Priority to ES06820232T priority patent/ES2390134T3/es
Publication of FR2898357A1 publication Critical patent/FR2898357A1/fr
Priority to HK09102641.0A priority patent/HK1124780A1/xx
Application granted granted Critical
Publication of FR2898357B1 publication Critical patent/FR2898357B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18—[b, e]-condensed with two six-membered rings
    • C07D279/20—[b, e]-condensed with two six-membered rings with hydrogen atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/22—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR0601999A 2005-10-21 2006-03-07 Derives d'amidine et leurs applications a titre de medicament Active FR2898357B1 (fr)

Priority Applications (12)

Application Number Priority Date Filing Date Title
FR0601999A FR2898357B1 (fr) 2006-03-07 2006-03-07 Derives d'amidine et leurs applications a titre de medicament
EP06820232A EP1954288B1 (fr) 2005-10-21 2006-10-18 Derives d'amidine et leurs applications a titre de medicament
US12/090,991 US7659266B2 (en) 2005-10-21 2006-10-18 Amidine derivatives and their applications as a medicament
PT06820232T PT1954288E (pt) 2005-10-21 2006-10-18 Derivados de amidina e suas utilizações como medicamento
DK06820232.4T DK1954288T3 (da) 2005-10-21 2006-10-18 Amidin-derivater og anvendelse deraf som lægemiddel
CA002626591A CA2626591A1 (fr) 2005-10-21 2006-10-18 Derives d'amidine et leurs applications a titre de medicament
CN2006800388504A CN101291676B (zh) 2005-10-21 2006-10-18 脒衍生物以及其作为药物的应用
JP2008536083A JP5280850B2 (ja) 2005-10-21 2006-10-18 アミジン誘導体及びその薬剤としての使用
PCT/FR2006/002338 WO2007045761A1 (fr) 2005-10-21 2006-10-18 Derives d'amidine et leurs applications a titre de medicament
ES06820232T ES2390134T3 (es) 2005-10-21 2006-10-18 Derivados de amidina y sus aplicaciones como medicamento
PL06820232T PL1954288T3 (pl) 2005-10-21 2006-10-18 Pochodne amidyny i ich zastosowanie jako leków
HK09102641.0A HK1124780A1 (en) 2005-10-21 2009-03-19 Amidine derivatives and their uses as medicine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0601999A FR2898357B1 (fr) 2006-03-07 2006-03-07 Derives d'amidine et leurs applications a titre de medicament

Publications (2)

Publication Number Publication Date
FR2898357A1 FR2898357A1 (fr) 2007-09-14
FR2898357B1 true FR2898357B1 (fr) 2012-02-17

Family

ID=36763287

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0601999A Active FR2898357B1 (fr) 2005-10-21 2006-03-07 Derives d'amidine et leurs applications a titre de medicament

Country Status (1)

Country Link
FR (1) FR2898357B1 (fr)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE318809T1 (de) * 1999-11-05 2006-03-15 Sod Conseils Rech Applic Heterocyclische verbindungen und ihre verwendung als medikamente
FR2863268B1 (fr) * 2003-12-09 2006-02-24 Sod Conseils Rech Applic Nouveaux derives du 2-hydroxytetrahydrofuranne et leur application a titre de medicaments
FR2867979B1 (fr) * 2004-03-29 2006-06-30 Sod Conseils Rech Applic Nouvelle application therapeutique d'un derive de la phenothiazine

Also Published As

Publication number Publication date
FR2898357A1 (fr) 2007-09-14

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