FR2875007A1 - Puce biologique comportant un reseau d'electrodes sur un substrat - Google Patents

Puce biologique comportant un reseau d'electrodes sur un substrat

Info

Publication number
FR2875007A1
FR2875007A1 FR0552655A FR0552655A FR2875007A1 FR 2875007 A1 FR2875007 A1 FR 2875007A1 FR 0552655 A FR0552655 A FR 0552655A FR 0552655 A FR0552655 A FR 0552655A FR 2875007 A1 FR2875007 A1 FR 2875007A1
Authority
FR
France
Prior art keywords
substrate
electrodes
network
chip
biological chip
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR0552655A
Other languages
English (en)
Other versions
FR2875007B1 (fr
Inventor
Franz Larmer
Heinz Eisenschmid
Michael Stumber
Marko Rocznik
Dick Scholten
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Robert Bosch GmbH
Original Assignee
Robert Bosch GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robert Bosch GmbH filed Critical Robert Bosch GmbH
Publication of FR2875007A1 publication Critical patent/FR2875007A1/fr
Application granted granted Critical
Publication of FR2875007B1 publication Critical patent/FR2875007B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3276—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a hybridisation with immobilised receptors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0645—Electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0819—Microarrays; Biochips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5088—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above confining liquids at a location by surface tension, e.g. virtual wells on plates, wires

Abstract

Puce biologique (1) comportant un réseau d'électrodes (2) sur un substrat (5) pour la détection électrique notamment capacitive de molécules biochimiques. Des électrodes (E1, E2) du réseau d'électrodes (2) sont reliées par un conducteur électrique (10) à travers le substrat (5) à une surface de contact électroconductrice (15). Les surfaces de contact (15) prévues sur le côté (20) du substrat (5) à l'opposé de celui du réseau d'électrodes (2) constituent sur ce côté (20) les surfaces de contact le plan le plus extrême du substrat (5). L'invention concerne également un procédé de fabrication d'une telle puce et un procédé de mise en contact électrique de la puce et d'une électronique d'exploitation.
FR0552655A 2004-09-03 2005-09-02 Puce biologique comportant un reseau d'electrodes sur un substrat Expired - Fee Related FR2875007B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102004042729.1A DE102004042729B4 (de) 2004-09-03 2004-09-03 Bio-Chip mit einem Elektrodenarray auf einem Substrat

Publications (2)

Publication Number Publication Date
FR2875007A1 true FR2875007A1 (fr) 2006-03-10
FR2875007B1 FR2875007B1 (fr) 2013-12-20

Family

ID=35852011

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0552655A Expired - Fee Related FR2875007B1 (fr) 2004-09-03 2005-09-02 Puce biologique comportant un reseau d'electrodes sur un substrat

Country Status (4)

Country Link
US (1) US20060105449A1 (fr)
DE (1) DE102004042729B4 (fr)
FR (1) FR2875007B1 (fr)
IT (1) ITMI20051622A1 (fr)

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EP2371454A1 (fr) * 2010-03-31 2011-10-05 Tecan Trading AG Procédé de mesure capacitif et dispositif pour la détection du niveau de remplissage et appareil de laboratoire en étant équipé
US8763454B2 (en) 2010-03-31 2014-07-01 Tecan Trading Ag Capacitive measuring method and apparatus for fill level detection and correspondingly equipped laboratory equipment

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JP2010509577A (ja) * 2006-11-09 2010-03-25 ナノアイデント テクノロジーズ アクチェンゲゼルシャフト 薄膜光センサを備えるタイタプレート
DE102008018922B4 (de) * 2007-04-17 2011-07-21 C2Cure Inc., Del. Bildgebende Systeme und Verfahren, insbesondere zur Verwendung mit einem bei offener Chirurgie verwendeten Instrument
US8017982B2 (en) * 2007-06-12 2011-09-13 Micron Technology, Inc. Imagers with contact plugs extending through the substrates thereof and imager fabrication methods
GB0723725D0 (en) * 2007-12-05 2008-01-16 Ge Healthcare Uk Ltd Apparatus and method for detecting dna damage
US8404192B2 (en) * 2008-04-25 2013-03-26 Ben H. Liu Biochips and related automated analyzers and methods
US7960282B2 (en) * 2009-05-21 2011-06-14 Globalfoundries Singapore Pte. Ltd. Method of manufacture an integrated circuit system with through silicon via
WO2011011669A1 (fr) * 2009-07-23 2011-01-27 University Of Wyoming Procédés et compositions pour la détection de matériaux biologiques à l'aide de dispositifs microfluidiques
EP2336758B1 (fr) * 2009-12-16 2012-08-29 Nxp B.V. Capteur capacitif
KR101363157B1 (ko) * 2010-10-07 2014-02-26 주식회사 세라젬메디시스 입체적 구조의 바이오센서 및 그 제조 방법
US8986523B2 (en) * 2012-01-19 2015-03-24 International Business Machines Corporation Biosensor capacitor
DE102013016390A1 (de) * 2013-10-01 2015-04-02 Testo Ag Kapazitiver Ölsensor
DE102014210122A1 (de) 2014-05-27 2015-12-03 Robert Bosch Gmbh Vorrichtung zum Bestimmen eines Werts einer zu messenden Eigenschaft eines Fluids, Verfahren zum Betreiben einer Vorrichtung zum Bestimmen eines Werts einer zu messenden Eigenschaft eines Fluids sowie Verfahren zum Herstellen einer Vorrichtung zum Bestimmen eines Werts einer zu messenden Eigenschaft eines Fluids
US9658190B2 (en) 2014-12-18 2017-05-23 Genia Technologies, Inc. Printed electrode
GB201522323D0 (en) 2015-12-17 2016-02-03 Vrije Universiteit Brussel And Katholieke Universiteit Leuven Systems and methods for conducting electrochemical impedance spectroscopy
JP7080489B2 (ja) 2016-01-28 2022-06-06 ロズウェル バイオテクノロジーズ，インコーポレイテッド 超パラレルｄｎａ配列決定装置
US11624725B2 (en) 2016-01-28 2023-04-11 Roswell Blotechnologies, Inc. Methods and apparatus for measuring analytes using polymerase in large scale molecular electronics sensor arrays
CA3053103A1 (fr) 2016-02-09 2017-08-17 Roswell Biotechnologies, Inc. Sequencage de l'adn et du genome sans marqueur electronique
US10597767B2 (en) 2016-02-22 2020-03-24 Roswell Biotechnologies, Inc. Nanoparticle fabrication
US9829456B1 (en) * 2016-07-26 2017-11-28 Roswell Biotechnologies, Inc. Method of making a multi-electrode structure usable in molecular sensing devices
KR102622275B1 (ko) 2017-01-10 2024-01-05 로스웰 바이오테크놀로지스 인코포레이티드 Dna 데이터 저장을 위한 방법들 및 시스템들
CN110520517A (zh) 2017-01-19 2019-11-29 罗斯威尔生命技术公司 包括二维层材料的固态测序装置
US10508296B2 (en) 2017-04-25 2019-12-17 Roswell Biotechnologies, Inc. Enzymatic circuits for molecular sensors
EP3615685A4 (fr) 2017-04-25 2021-01-20 Roswell Biotechnologies, Inc Circuits enzymatiques pour capteurs moléculaires
EP4023764A3 (fr) 2017-05-09 2022-09-21 Roswell Biotechnologies, Inc. Circuits de sonde de liaison pour capteurs moléculaires
EP3676389A4 (fr) 2017-08-30 2021-06-02 Roswell Biotechnologies, Inc Capteurs électroniques moléculaires à enzyme processive pour le stockage de données d'adn
EP3694990A4 (fr) 2017-10-10 2022-06-15 Roswell Biotechnologies, Inc. Procédés, appareil et systèmes pour le stockage de données d'adn sans amplification
US11402376B2 (en) 2018-03-23 2022-08-02 University Of Wyoming Methods and devices for detection of biological materials using electric field assisted rapid analyte capture
CN108548857A (zh) * 2018-04-18 2018-09-18 山东省科学院生物研究所 一种生物电极板及生物电子检测装置
DE102019219955A1 (de) * 2019-12-18 2021-06-24 Robert Bosch Gmbh Microarray
WO2022060837A1 (fr) * 2020-09-15 2022-03-24 Murata Manufacturing Co., Ltd. Structure d'électrode de tranchée pour la mesure de biosignal

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DE10015818A1 (de) * 2000-03-30 2001-10-18 Infineon Technologies Ag Biosensor und Verfahren zum Ermitteln makromolekularer Biopolymere mit einem Biosensor
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US6649402B2 (en) * 2001-06-22 2003-11-18 Wisconsin Alumni Research Foundation Microfabricated microbial growth assay method and apparatus
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2371454A1 (fr) * 2010-03-31 2011-10-05 Tecan Trading AG Procédé de mesure capacitif et dispositif pour la détection du niveau de remplissage et appareil de laboratoire en étant équipé
CH702942A1 (de) * 2010-03-31 2011-10-14 Tecan Trading Ag Kapazitives Messverfahren und Vorrichtung zur Füllstandsdetektion und entsprechend ausgestattetes Laborgerät.
US8763454B2 (en) 2010-03-31 2014-07-01 Tecan Trading Ag Capacitive measuring method and apparatus for fill level detection and correspondingly equipped laboratory equipment

Also Published As

Publication number Publication date
US20060105449A1 (en) 2006-05-18
DE102004042729A1 (de) 2006-03-23
ITMI20051622A1 (it) 2006-03-04
DE102004042729B4 (de) 2018-02-01
FR2875007B1 (fr) 2013-12-20

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