FR2867980B1 - Utilisation de l'acide masticadienonique en tant qu'inhibiteur de l'adn polymerase beta - Google Patents

Utilisation de l'acide masticadienonique en tant qu'inhibiteur de l'adn polymerase beta

Info

Publication number
FR2867980B1
FR2867980B1 FR0402972A FR0402972A FR2867980B1 FR 2867980 B1 FR2867980 B1 FR 2867980B1 FR 0402972 A FR0402972 A FR 0402972A FR 0402972 A FR0402972 A FR 0402972A FR 2867980 B1 FR2867980 B1 FR 2867980B1
Authority
FR
France
Prior art keywords
dna polymerase
polymerase inhibitor
masticadienonic acid
beta dna
beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0402972A
Other languages
English (en)
Other versions
FR2867980A1 (fr
Inventor
Georges Massiot
Christophe Long
Frederic Ausseil
Martine Knibiehler
Yvan Canitrot
Jean Sebastien Hoffmann
Christophe Cazaux
Pierre Benaim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Pierre Fabre Medicament SA
Original Assignee
Centre National de la Recherche Scientifique CNRS
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, Pierre Fabre Medicament SA filed Critical Centre National de la Recherche Scientifique CNRS
Priority to FR0402972A priority Critical patent/FR2867980B1/fr
Priority to PCT/FR2005/000701 priority patent/WO2005094837A1/fr
Publication of FR2867980A1 publication Critical patent/FR2867980A1/fr
Application granted granted Critical
Publication of FR2867980B1 publication Critical patent/FR2867980B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR0402972A 2004-03-23 2004-03-23 Utilisation de l'acide masticadienonique en tant qu'inhibiteur de l'adn polymerase beta Expired - Fee Related FR2867980B1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR0402972A FR2867980B1 (fr) 2004-03-23 2004-03-23 Utilisation de l'acide masticadienonique en tant qu'inhibiteur de l'adn polymerase beta
PCT/FR2005/000701 WO2005094837A1 (fr) 2004-03-23 2005-03-23 Utilisation de l’acide masticadienonique en tant qu’inhibiteur de l’adn polymerase beta

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0402972A FR2867980B1 (fr) 2004-03-23 2004-03-23 Utilisation de l'acide masticadienonique en tant qu'inhibiteur de l'adn polymerase beta

Publications (2)

Publication Number Publication Date
FR2867980A1 FR2867980A1 (fr) 2005-09-30
FR2867980B1 true FR2867980B1 (fr) 2006-07-14

Family

ID=34944453

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0402972A Expired - Fee Related FR2867980B1 (fr) 2004-03-23 2004-03-23 Utilisation de l'acide masticadienonique en tant qu'inhibiteur de l'adn polymerase beta

Country Status (2)

Country Link
FR (1) FR2867980B1 (fr)
WO (1) WO2005094837A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101875984B1 (ko) 2010-09-07 2018-07-06 레제네라 파마 리미티드 매스틱 검의 산성 추출물을 포함하는 조성물
KR20180054821A (ko) 2015-09-24 2018-05-24 레제네라 파마 리미티드 트리테르페노이드 포함 조성물
ES2904263T3 (es) 2015-09-24 2022-04-04 Regenera Pharma Ltd Composiciones que comprenden triterpenoides para el tratamiento de la enfermedad de Alzheimer y la enfermedad de Parkinson
BR112019004488A2 (pt) 2016-09-08 2019-05-28 Regenera Pharma Ltd composições compreendendo triterpenoides e utilizações das mesmas para tratamento de neuropatia ótica
CN109922798A (zh) 2016-09-08 2019-06-21 瑞吉纳拉制药公司 包括乳香胶的酸性提取物的组合物及其用于治疗视神经病变的用途
CN108715845B (zh) * 2018-05-15 2021-09-24 郑州大学 一种食管上皮组织polβ特异性敲除小鼠食管癌前病变模型的构建方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003241345A1 (en) * 2002-05-01 2003-11-17 Lavipharm S.A. Use of mastic and its components for the control of microbial infections

Also Published As

Publication number Publication date
WO2005094837A1 (fr) 2005-10-13
FR2867980A1 (fr) 2005-09-30

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20071130