FR2856792A1 - METHOD AND DEVICE FOR ASSAYING A BIOLOGICAL OR CHEMICAL SAMPLE - Google Patents

METHOD AND DEVICE FOR ASSAYING A BIOLOGICAL OR CHEMICAL SAMPLE

Info

Publication number
FR2856792A1
FR2856792A1 FR0350270A FR0350270A FR2856792A1 FR 2856792 A1 FR2856792 A1 FR 2856792A1 FR 0350270 A FR0350270 A FR 0350270A FR 0350270 A FR0350270 A FR 0350270A FR 2856792 A1 FR2856792 A1 FR 2856792A1
Authority
FR
France
Prior art keywords
biological
sample
assaying
chemical sample
image
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR0350270A
Other languages
French (fr)
Other versions
FR2856792B1 (en
Inventor
Francois Perraut
Emmanuelle Schultz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
Commissariat a lEnergie Atomique CEA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0350270A priority Critical patent/FR2856792B1/en
Application filed by Commissariat a lEnergie Atomique CEA filed Critical Commissariat a lEnergie Atomique CEA
Priority to US10/560,973 priority patent/US7396650B2/en
Priority to AU2004252258A priority patent/AU2004252258A1/en
Priority to EP04767851A priority patent/EP1639349A1/en
Priority to PCT/FR2004/050289 priority patent/WO2005001449A1/en
Priority to CA002530382A priority patent/CA2530382A1/en
Priority to JP2006516356A priority patent/JP2007516411A/en
Publication of FR2856792A1 publication Critical patent/FR2856792A1/en
Application granted granted Critical
Publication of FR2856792B1 publication Critical patent/FR2856792B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/51—Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N15/0205—Investigating particle size or size distribution by optical means
    • G01N15/0227—Investigating particle size or size distribution by optical means using imaging; using holography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition

Landscapes

  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

L'invention concerne un procédé de dosage d'un échantillon biologique ou chimique comportant les étapes suivantes :- éclairement de l'échantillon (10) au moyen d'un faisceau lumineux (17) issu d'une source (11),- réalisation d'une image comprenant l'image du faisceau (18) diffusé par l'échantillon (10),- analyse de l'image selon des critères de référence,- extraction d'une information spécifique à l'interaction faisceau lumineux/échantillon,- calcul du dosage.L'invention concerne également un dispositif de dosage d'un échantillon biologique ou chimique.The invention relates to a method for assaying a biological or chemical sample comprising the following steps: - illumination of the sample (10) by means of a light beam (17) coming from a source (11), - realization of an image comprising the image of the beam (18) scattered by the sample (10), - analysis of the image according to reference criteria, - extraction of information specific to the light beam / sample interaction, - Calculation of the dosage. The invention also relates to a device for dosing a biological or chemical sample.

FR0350270A 2003-06-27 2003-06-27 METHOD AND DEVICE FOR ASSAYING A BIOLOGICAL OR CHEMICAL SAMPLE Expired - Fee Related FR2856792B1 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
FR0350270A FR2856792B1 (en) 2003-06-27 2003-06-27 METHOD AND DEVICE FOR ASSAYING A BIOLOGICAL OR CHEMICAL SAMPLE
AU2004252258A AU2004252258A1 (en) 2003-06-27 2004-06-24 Method for dosing a biological or chemical sample
EP04767851A EP1639349A1 (en) 2003-06-27 2004-06-24 Method for dosing a biological or chemical sample
PCT/FR2004/050289 WO2005001449A1 (en) 2003-06-27 2004-06-24 Method for dosing a biological or chemical sample
US10/560,973 US7396650B2 (en) 2003-06-27 2004-06-24 Method for dosing a biological or chemical sample
CA002530382A CA2530382A1 (en) 2003-06-27 2004-06-24 Method for dosing a biological or chemical sample
JP2006516356A JP2007516411A (en) 2003-06-27 2004-06-24 Method for quantitative analysis of biological or chemical samples

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0350270A FR2856792B1 (en) 2003-06-27 2003-06-27 METHOD AND DEVICE FOR ASSAYING A BIOLOGICAL OR CHEMICAL SAMPLE

Publications (2)

Publication Number Publication Date
FR2856792A1 true FR2856792A1 (en) 2004-12-31
FR2856792B1 FR2856792B1 (en) 2006-09-15

Family

ID=33515557

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0350270A Expired - Fee Related FR2856792B1 (en) 2003-06-27 2003-06-27 METHOD AND DEVICE FOR ASSAYING A BIOLOGICAL OR CHEMICAL SAMPLE

Country Status (6)

Country Link
EP (1) EP1639349A1 (en)
JP (1) JP2007516411A (en)
AU (1) AU2004252258A1 (en)
CA (1) CA2530382A1 (en)
FR (1) FR2856792B1 (en)
WO (1) WO2005001449A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021089841A1 (en) * 2019-11-08 2021-05-14 Nanotemper Technologies Gmbh Characterization of particles in solution

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5097590B2 (en) * 2008-03-26 2012-12-12 富士フイルム株式会社 Raman signal measuring method and Raman signal measuring apparatus
FR2938917B1 (en) * 2008-11-26 2018-05-18 Formulaction DEVICE FOR ANALYZING A POLYPHASIC MIXTURE VIA A LIGHT BEAM RETRODIFFUSED THEREBY

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3797937A (en) * 1972-03-01 1974-03-19 Environmental Systems Corp System for making particle measurements
FR2522150A1 (en) * 1982-02-23 1983-08-26 Strahlen Umweltforsch Gmbh DEVICE FOR THE QUANTITATIVE DETECTION OF BIOCHEMICAL REACTIONS
US5097135A (en) * 1989-08-24 1992-03-17 Olympus Optical Co., Ltd. Method of forming a two-dimensional distribution image of ion concentration in a cell
US5827660A (en) * 1996-08-09 1998-10-27 University Of Massachusetts Caged fluorochrome-labeled probes and subtraction of autoflourescence background

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5323010A (en) * 1992-12-01 1994-06-21 I.S.S. (Usa) Inc. Time resolved optical array detectors and CCD cameras for frequency domain fluorometry and/or phosphorimetry
JP3224640B2 (en) * 1993-07-30 2001-11-05 三菱重工業株式会社 Apparatus and method for measuring concentration by LIF
JP3290786B2 (en) * 1993-11-26 2002-06-10 シスメックス株式会社 Particle analyzer
JPH0933441A (en) * 1995-07-19 1997-02-07 Toray Ind Inc Method and device for judging reaction pattern
JPH1078398A (en) * 1996-09-02 1998-03-24 Bunshi Bio Photonics Kenkyusho:Kk Fluorescence sevice life measuring device and method
DE19915310A1 (en) * 1999-04-03 2000-10-05 Bayer Ag Diffusion-controlling sensor layer
JP2001083092A (en) * 1999-09-17 2001-03-30 Kowa Co Fluorescent particle image pickup device
JP3576523B2 (en) * 2000-12-26 2004-10-13 オリンパス株式会社 Fluorescence luminance measurement method and apparatus
JP3715248B2 (en) * 2001-03-21 2005-11-09 オリンパス株式会社 Biochemical inspection method

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3797937A (en) * 1972-03-01 1974-03-19 Environmental Systems Corp System for making particle measurements
FR2522150A1 (en) * 1982-02-23 1983-08-26 Strahlen Umweltforsch Gmbh DEVICE FOR THE QUANTITATIVE DETECTION OF BIOCHEMICAL REACTIONS
US5097135A (en) * 1989-08-24 1992-03-17 Olympus Optical Co., Ltd. Method of forming a two-dimensional distribution image of ion concentration in a cell
US5827660A (en) * 1996-08-09 1998-10-27 University Of Massachusetts Caged fluorochrome-labeled probes and subtraction of autoflourescence background

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ULANOWSKI Z ET AL: "LASER DIFFRACTOMETER FOR SINGLE-PARTICLE SCATTERING MEASUREMENTS", MEASUREMENT SCIENCE AND TECHNOLOGY, IOP PUBLISHING, BRISTOL, GB, vol. 13, no. 3, March 2002 (2002-03-01), pages 292 - 296, XP001163542, ISSN: 0957-0233 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021089841A1 (en) * 2019-11-08 2021-05-14 Nanotemper Technologies Gmbh Characterization of particles in solution
WO2021089834A1 (en) * 2019-11-08 2021-05-14 Nanotemper Technologies Gmbh Characterization of particles in solution

Also Published As

Publication number Publication date
JP2007516411A (en) 2007-06-21
FR2856792B1 (en) 2006-09-15
AU2004252258A1 (en) 2005-01-06
EP1639349A1 (en) 2006-03-29
CA2530382A1 (en) 2005-01-06
WO2005001449A1 (en) 2005-01-06

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Year of fee payment: 13

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Effective date: 20170228