FR2756491B1 - Composition transfectante utile en therapie genique associan t a un virus recombinant incorporant un acide nucleique exog ene, un agent de transfection non viral et non plasmidique - Google Patents

Composition transfectante utile en therapie genique associan t a un virus recombinant incorporant un acide nucleique exog ene, un agent de transfection non viral et non plasmidique

Info

Publication number
FR2756491B1
FR2756491B1 FR9614693A FR9614693A FR2756491B1 FR 2756491 B1 FR2756491 B1 FR 2756491B1 FR 9614693 A FR9614693 A FR 9614693A FR 9614693 A FR9614693 A FR 9614693A FR 2756491 B1 FR2756491 B1 FR 2756491B1
Authority
FR
France
Prior art keywords
transfecting
exog
plasmidic
ene
viral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9614693A
Other languages
English (en)
Other versions
FR2756491A1 (fr
Inventor
Nathalie Aubailly
Nathalie Ratet
Didier Branellec
Patrick Benoit
Abderrahim Mahfoudi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Rhone Poulenc Rorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer SA filed Critical Rhone Poulenc Rorer SA
Priority to FR9614693A priority Critical patent/FR2756491B1/fr
Priority to ZA9701070A priority patent/ZA971070B/xx
Priority to IL13005397A priority patent/IL130053A0/xx
Priority to CZ991882A priority patent/CZ188299A3/cs
Priority to JP52437898A priority patent/JP2001514485A/ja
Priority to EP97948959A priority patent/EP0948636A1/fr
Priority to PCT/FR1997/002157 priority patent/WO1998023765A1/fr
Priority to CA002272637A priority patent/CA2272637A1/fr
Priority to KR1019990704738A priority patent/KR20000057307A/ko
Priority to SK709-99A priority patent/SK70999A3/sk
Priority to BR9713434-1A priority patent/BR9713434A/pt
Priority to HU9904201A priority patent/HUP9904201A3/hu
Priority to AU74010/98A priority patent/AU737846B2/en
Publication of FR2756491A1 publication Critical patent/FR2756491A1/fr
Application granted granted Critical
Publication of FR2756491B1 publication Critical patent/FR2756491B1/fr
Priority to NO992577A priority patent/NO992577L/no
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2810/00—Vectors comprising a targeting moiety
    • C12N2810/10—Vectors comprising a non-peptidic targeting moiety
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2810/00—Vectors comprising a targeting moiety
    • C12N2810/40—Vectors comprising a peptide as targeting moiety, e.g. a synthetic peptide, from undefined source
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2810/00—Vectors comprising a targeting moiety
    • C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2810/00—Vectors comprising a targeting moiety
    • C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
    • C12N2810/80—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates
    • C12N2810/85—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian
    • C12N2810/859—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian from immunoglobulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
FR9614693A 1996-02-12 1996-11-29 Composition transfectante utile en therapie genique associan t a un virus recombinant incorporant un acide nucleique exog ene, un agent de transfection non viral et non plasmidique Expired - Fee Related FR2756491B1 (fr)

Priority Applications (14)

Application Number Priority Date Filing Date Title
FR9614693A FR2756491B1 (fr) 1996-11-29 1996-11-29 Composition transfectante utile en therapie genique associan t a un virus recombinant incorporant un acide nucleique exog ene, un agent de transfection non viral et non plasmidique
ZA9701070A ZA971070B (en) 1996-02-12 1997-02-10 Transfectant composition useful in gene therapy asA water control gate. sociating with a recombinant virus incorporating an exogenous nucleic acid and a non-viral and non-plasmid transfection agent.
HU9904201A HUP9904201A3 (en) 1996-11-29 1997-11-28 Transfecting composition usable in gene therapy combining a recombinant virus incorporating an exogenous nucleic acid, a non-viral and non-plasmid transfecting agent
JP52437898A JP2001514485A (ja) 1996-11-29 1997-11-28 外来核酸を組込んだ組換えウイルスと非ウイルス性非プラスミド性トランスフェクション用物質との組合せから成る遺伝子治療に有用なトランスフェクション用組成物
EP97948959A EP0948636A1 (fr) 1996-11-29 1997-11-28 Composition transfectante utile en therapie genique associant a un virus recombinant incorporant un acide nucleique exogene, un agent de transfection non viral et non plasmidique
PCT/FR1997/002157 WO1998023765A1 (fr) 1996-11-29 1997-11-28 Composition transfectante utile en therapie genique associant a un virus recombinant incorporant un acide nucleique exogene, un agent de transfection non viral et non plasmidique
CA002272637A CA2272637A1 (fr) 1996-11-29 1997-11-28 Composition transfectante utile en therapie genique associant a un virus recombinant incorporant un acide nucleique exogene, un agent de transfection non viral et non plasmidique
KR1019990704738A KR20000057307A (ko) 1996-11-29 1997-11-28 외인성 핵산이 이입된 재조합 바이러스, 비-바이러스 및비-플라스미드 형질 감염제를 병용하는 유전자 요법에 유용한형질감염 조성물
IL13005397A IL130053A0 (en) 1996-11-29 1997-11-28 Transfecting composition usable in gene therapy combining a recombinant virus incorporating an exogenous nucleic acid a non-viral and non-plasmid transfecting agent
BR9713434-1A BR9713434A (pt) 1996-11-29 1997-11-28 Composição transfectante útil em terapia gênica e células tratadas pela mesma
CZ991882A CZ188299A3 (cs) 1996-11-29 1997-11-28 Transfekční přípravek vhodný pro genovou terapii, který obsahuje rekombinantní virus a transfekční činidlo
AU74010/98A AU737846B2 (en) 1996-11-29 1997-11-28 Transfectant composition useful in gene therapy associating with a recombinant virus incorporating an exogenous nucleic acid and a non-viral and non-plasmid transfection agent
SK709-99A SK70999A3 (en) 1996-11-29 1997-11-28 Transfecting composition usable in gene therapy combining a recombinant virus incorporating an exogenous nucleic acid, a non-viral and non-plasmid transfecting agent
NO992577A NO992577L (no) 1996-11-29 1999-05-28 Transfeksjonsblanding for anvendelse ved genterapi og som kombinerer en rekombinant virus som inkorporerer en exogen nukleinsyre, med et ikke-viralt, ikke-plasmidisk transfeksjonsmiddel

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9614693A FR2756491B1 (fr) 1996-11-29 1996-11-29 Composition transfectante utile en therapie genique associan t a un virus recombinant incorporant un acide nucleique exog ene, un agent de transfection non viral et non plasmidique

Publications (2)

Publication Number Publication Date
FR2756491A1 FR2756491A1 (fr) 1998-06-05
FR2756491B1 true FR2756491B1 (fr) 1999-01-08

Family

ID=9498192

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9614693A Expired - Fee Related FR2756491B1 (fr) 1996-02-12 1996-11-29 Composition transfectante utile en therapie genique associan t a un virus recombinant incorporant un acide nucleique exog ene, un agent de transfection non viral et non plasmidique

Country Status (13)

Country Link
EP (1) EP0948636A1 (fr)
JP (1) JP2001514485A (fr)
KR (1) KR20000057307A (fr)
AU (1) AU737846B2 (fr)
BR (1) BR9713434A (fr)
CA (1) CA2272637A1 (fr)
CZ (1) CZ188299A3 (fr)
FR (1) FR2756491B1 (fr)
HU (1) HUP9904201A3 (fr)
IL (1) IL130053A0 (fr)
NO (1) NO992577L (fr)
SK (1) SK70999A3 (fr)
WO (1) WO1998023765A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100764890B1 (ko) * 2005-11-14 2007-10-09 한국화학연구원 폴리에틸렌이민과 인지질을 접합하여 제조된 리포솜을이용한 항암주사제 및 이의 제조방법
EP2117304A4 (fr) * 2007-02-07 2011-08-24 Gradalis Inc Procédés et compositions pour moduler une production d'acide sialique et traitement de myopathie à corps d'inclusion héréditaire
KR100980395B1 (ko) 2008-06-27 2010-09-07 재단법인서울대학교산학협력재단 비-바이러스성 유전자 전달체용 중합체/유전자 복합체
JP5944622B2 (ja) * 2011-04-08 2016-07-05 株式会社ブリヂストン 遺伝子導入剤組成物
US9598713B2 (en) 2012-03-02 2017-03-21 Japanese Science And Technology Agency Method for constructing functional nucleic acid molecule, and nucleic acid combination to be used in said method

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2646161B1 (fr) * 1989-04-17 1991-07-05 Centre Nat Rech Scient Nouvelles lipopolyamines, leur preparation et leur emploi
US5552309A (en) * 1994-09-30 1996-09-03 Indiana University Foundation Use of polyols for improving the introduction of genetic material into cells
FR2727679B1 (fr) * 1994-12-05 1997-01-03 Rhone Poulenc Rorer Sa Nouveaux agents de transfection et leurs applications pharmaceutiques
FR2730637B1 (fr) * 1995-02-17 1997-03-28 Rhone Poulenc Rorer Sa Composition pharmaceutique contenant des acides nucleiques, et ses utilisations
FR2741066B1 (fr) * 1995-11-14 1997-12-12 Rhone Poulenc Rorer Sa Nouveaux agents de transfection et leurs applications pharmaceutiques

Also Published As

Publication number Publication date
EP0948636A1 (fr) 1999-10-13
NO992577L (no) 1999-07-28
AU737846B2 (en) 2001-08-30
BR9713434A (pt) 2000-02-01
HUP9904201A3 (en) 2002-01-28
CA2272637A1 (fr) 1998-06-04
AU7401098A (en) 1998-06-22
NO992577D0 (no) 1999-05-28
CZ188299A3 (cs) 1999-09-15
WO1998023765A1 (fr) 1998-06-04
IL130053A0 (en) 2000-02-29
JP2001514485A (ja) 2001-09-11
KR20000057307A (ko) 2000-09-15
SK70999A3 (en) 2000-03-13
FR2756491A1 (fr) 1998-06-05
HUP9904201A1 (hu) 2000-04-28

Similar Documents

Publication Publication Date Title
FR2712603B1 (fr) Virus recombinants, préparation et utilisation en thérapie génique.
ATE215990T1 (de) Zusammensetzung für das einbringen von nukleinsäure-komplexen in höhere eukaryotische zellen
FR2716893B1 (fr) Virus recombinants, leur préparation et leur utilisation thérapeutique.
FR2704234B1 (fr) Virus recombinants, preparation et utilisation en therapie genique.
DK0797678T3 (da) Hybrid adenovirus-AAV-virus og fremgangsmåder til anvendelse af dette
FR2718150B1 (fr) Virus recombinants, préparation et utilisation en thérapie génique.
EP1005376A4 (fr) Methodes et compositions utilisees en therapie genique dans le traitement de l'hemophilie
CA2364499A1 (fr) Transduction de cellules ressemblant a des fibroblastes ou a des macrophages et moyens a cet effet
FR2712602B1 (fr) Virus recombinants, préparation et utilisation en thérapie génique.
AU1927797A (en) Vectors based on recombinant defective viral genomes, and their use in the formulation of vaccines
FR2756491B1 (fr) Composition transfectante utile en therapie genique associan t a un virus recombinant incorporant un acide nucleique exog ene, un agent de transfection non viral et non plasmidique
FR2717495B1 (fr) Virus recombinants, préparation et utilisation en thérapie génique.
IL133032A0 (en) Gene delivery vectors provided with a tissue tropism for smooth muscle cells and/or endothelial cells
MX9702078A (es) Adenovirus que comprenden dos genes terapeuticos: suicida e inmunoestimulante.
FR2717496B1 (fr) Virus recombinants, préparation et utilisation en thérapie génique.
NZ511168A (en) Recombinant CELO virus and CELO virus DNA
FI964784A0 (fi) Yhdistelmä-DNA-viruksia, valmistus ja käyttö geeniterapiassa
FR2717823B1 (fr) Virus recombinants, préparation et utilisation en thérapie génique.
FR2726575B1 (fr) Virus recombinants, preparation et utilisation en therapie genique
FR2717497B1 (fr) Virus recombinants, préparation et utilisation en thérapie génique.
ZA971070B (en) Transfectant composition useful in gene therapy asA water control gate. sociating with a recombinant virus incorporating an exogenous nucleic acid and a non-viral and non-plasmid transfection agent.
BR0009666A (pt) Adenovìrus recombinante e mutante derivado de adenovìrus bovino tipo 1

Legal Events

Date Code Title Description
CD Change of name or company name
ST Notification of lapse