FR2750433B1 - Procede de production d'adenovirus recombinants - Google Patents
Procede de production d'adenovirus recombinantsInfo
- Publication number
- FR2750433B1 FR2750433B1 FR9608164A FR9608164A FR2750433B1 FR 2750433 B1 FR2750433 B1 FR 2750433B1 FR 9608164 A FR9608164 A FR 9608164A FR 9608164 A FR9608164 A FR 9608164A FR 2750433 B1 FR2750433 B1 FR 2750433B1
- Authority
- FR
- France
- Prior art keywords
- producing recombinant
- recombinant adenoviruses
- adenoviruses
- producing
- recombinant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/145—Ultrafiltration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/34—Size selective separation, e.g. size exclusion chromatography, gel filtration, permeation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
- B01D15/361—Ion-exchange
- B01D15/363—Anion-exchange
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J41/00—Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
- B01J41/20—Anion exchangers for chromatographic processes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/12—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the preparation of the feed
- B01D15/125—Pre-filtration
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10351—Methods of production or purification of viral material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Water Supply & Treatment (AREA)
- Virology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Priority Applications (17)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9608164A FR2750433B1 (fr) | 1996-07-01 | 1996-07-01 | Procede de production d'adenovirus recombinants |
SK1810-98A SK181098A3 (en) | 1996-07-01 | 1997-06-20 | Method for producing recombinant adenovirus |
EP97930560A EP0944717A1 (fr) | 1996-07-01 | 1997-06-20 | Procede de production d'adenovirus recombinants |
US09/202,545 US6485958B2 (en) | 1996-07-01 | 1997-06-20 | Method for producing recombinant adenovirus |
AU34470/97A AU3447097A (en) | 1996-07-01 | 1997-06-20 | Method for producing recombinant adenovirus |
BR9710030A BR9710030A (pt) | 1996-07-01 | 1997-06-20 | Processo de produção de adenovírus recombinantes processo de purificação de adenovírus recombinantes a partir de um meio biológico preparação viral purificada composição farmacêutica e utilização de iodixanol-5,5'-[(2-Hidroxipropil-1,3-Propanottl)-Bis[N,N'-Bis(2,3-Didroxipropil-2,4,6-Triodo-1,3-Benzenocarboxamida] |
PCT/FR1997/001107 WO1998000524A1 (fr) | 1996-07-01 | 1997-06-20 | Procede de production d'adenovirus recombinants |
HU0001271A HU224558B1 (hu) | 1996-07-01 | 1997-06-20 | Eljárás rekombináns adenovírusok tisztítására |
KR1020057007148A KR20050043996A (ko) | 1996-07-01 | 1997-06-20 | 재조합 아데노바이러스의 제조방법 |
JP10503872A JP2000514290A (ja) | 1996-07-01 | 1997-06-20 | 組換えアデノウイルスの製造方法 |
CA002258158A CA2258158A1 (fr) | 1996-07-01 | 1997-06-20 | Procede de production d'adenovirus recombinants |
IL12769297A IL127692A0 (en) | 1996-07-01 | 1997-06-20 | Method for producing recombinant adenovirus |
CZ984383A CZ438398A3 (cs) | 1996-07-01 | 1997-06-20 | Způsob přípravy rekombinantních adenovirů |
ZA9705823A ZA975823B (en) | 1996-07-01 | 1997-06-30 | Process for the production of recombinant adenoviruses. |
NO986202A NO986202L (no) | 1996-07-01 | 1998-12-30 | FremgangsmÕte for fremstilling av rekombinant adÚnovirus |
US10/267,865 US6905862B2 (en) | 1996-07-01 | 2002-10-10 | Method for producing recombinant adenovirus |
US11/086,678 US20050287657A1 (en) | 1996-07-01 | 2005-03-23 | Method for producing recombinant adenovirus |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9608164A FR2750433B1 (fr) | 1996-07-01 | 1996-07-01 | Procede de production d'adenovirus recombinants |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2750433A1 FR2750433A1 (fr) | 1998-01-02 |
FR2750433B1 true FR2750433B1 (fr) | 1998-08-14 |
Family
ID=9493589
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR9608164A Expired - Fee Related FR2750433B1 (fr) | 1996-07-01 | 1996-07-01 | Procede de production d'adenovirus recombinants |
Country Status (2)
Country | Link |
---|---|
FR (1) | FR2750433B1 (fr) |
ZA (1) | ZA975823B (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6995006B2 (en) | 1997-09-05 | 2006-02-07 | Targeted Genetics Corporation | Methods for generating high titer helper-free preparations of released recombinant AAV vectors |
US6566118B1 (en) | 1997-09-05 | 2003-05-20 | Targeted Genetics Corporation | Methods for generating high titer helper-free preparations of released recombinant AAV vectors |
ES2541540T3 (es) * | 1998-09-04 | 2015-07-21 | Genzyme Corporation | Métodos para generar preparados exentos de helper de alto título de vectores de AAV recombinantes liberados |
EP2942393A1 (fr) * | 1998-09-04 | 2015-11-11 | Genzyme Corporation | Procédés pour produire des préparations de vecteurs aav recombinants de forte teneur dépourvues de virus assistants |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2705686B1 (fr) * | 1993-05-28 | 1995-08-18 | Transgene Sa | Nouveaux adénovirus défectifs et lignées de complémentation correspondantes. |
CA2181066A1 (fr) * | 1994-01-12 | 1995-07-20 | Hitoshi Kotani | Purification de vecteurs retroviraux |
FR2716893B1 (fr) * | 1994-03-03 | 1996-04-12 | Rhone Poulenc Rorer Sa | Virus recombinants, leur préparation et leur utilisation thérapeutique. |
AU2127395A (en) * | 1994-03-22 | 1995-10-09 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Highly efficient production and isolation of viral particles |
-
1996
- 1996-07-01 FR FR9608164A patent/FR2750433B1/fr not_active Expired - Fee Related
-
1997
- 1997-06-30 ZA ZA9705823A patent/ZA975823B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
FR2750433A1 (fr) | 1998-01-02 |
ZA975823B (en) | 1998-03-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
CD | Change of name or company name | ||
ST | Notification of lapse |
Effective date: 20080331 |