FR2737891B1 - Analogues chiraux de la 15-deoxyspergualine, procede de preparation et utilisation en therapeutique - Google Patents

Analogues chiraux de la 15-deoxyspergualine, procede de preparation et utilisation en therapeutique

Info

Publication number
FR2737891B1
FR2737891B1 FR9509884A FR9509884A FR2737891B1 FR 2737891 B1 FR2737891 B1 FR 2737891B1 FR 9509884 A FR9509884 A FR 9509884A FR 9509884 A FR9509884 A FR 9509884A FR 2737891 B1 FR2737891 B1 FR 2737891B1
Authority
FR
France
Prior art keywords
deoxyspergualin
preparation
therapeutic use
chiral analogs
chiral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9509884A
Other languages
English (en)
Other versions
FR2737891A1 (fr
Inventor
Philippe Durand
Patrice Renaut
Luc Lebreton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fournier Industrie et Sante SAS
Original Assignee
Fournier Industrie et Sante SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9509884A priority Critical patent/FR2737891B1/fr
Application filed by Fournier Industrie et Sante SAS filed Critical Fournier Industrie et Sante SAS
Priority to US08/722,168 priority patent/US5883132A/en
Priority to JP8524041A priority patent/JPH09511765A/ja
Priority to DE69600780T priority patent/DE69600780T2/de
Priority to EP96903066A priority patent/EP0755380B1/fr
Priority to DK96903066T priority patent/DK0755380T3/da
Priority to AT96903066T priority patent/ATE172189T1/de
Priority to PCT/FR1996/000203 priority patent/WO1996024579A1/fr
Priority to CA002187281A priority patent/CA2187281A1/fr
Priority to ES96903066T priority patent/ES2125714T3/es
Publication of FR2737891A1 publication Critical patent/FR2737891A1/fr
Application granted granted Critical
Publication of FR2737891B1 publication Critical patent/FR2737891B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/20—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C07C247/02—Compounds containing azido groups with azido groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C247/12—Compounds containing azido groups with azido groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR9509884A 1995-02-10 1995-08-17 Analogues chiraux de la 15-deoxyspergualine, procede de preparation et utilisation en therapeutique Expired - Fee Related FR2737891B1 (fr)

Priority Applications (10)

Application Number Priority Date Filing Date Title
FR9509884A FR2737891B1 (fr) 1995-08-17 1995-08-17 Analogues chiraux de la 15-deoxyspergualine, procede de preparation et utilisation en therapeutique
CA002187281A CA2187281A1 (fr) 1995-02-10 1996-02-07 Analogues de la 15-deoxyspergualine, leur utilisation en therapeutique et leur procede de preparation
DE69600780T DE69600780T2 (de) 1995-02-10 1996-02-07 15-deoxyspergualin-analoge verbindungen, ihre verwendung als therapeutika und verfahren zu ihrer herstellung
EP96903066A EP0755380B1 (fr) 1995-02-10 1996-02-07 Analogues de la 15-deoxyspergualine, leur utilisation en therapeutique et leur procede de preparation
DK96903066T DK0755380T3 (da) 1995-02-10 1996-02-07 15-deoxyspergualin-analoge, deres terapeutiske anvendelse og fremgangsmåde til fremstilling deraf
AT96903066T ATE172189T1 (de) 1995-02-10 1996-02-07 15-deoxyspergualin-analoge verbindungen, ihre verwendung als therapeutika und verfahren zu ihrer herstellung
US08/722,168 US5883132A (en) 1995-02-10 1996-02-07 15-deoxyspergualin analogs, their use in therapeutics and their method of preparation
JP8524041A JPH09511765A (ja) 1995-02-10 1996-02-07 １５−デオキシスペルグアリン類似体、その治療用途及びその調製方法
ES96903066T ES2125714T3 (es) 1995-02-10 1996-02-07 Compuesto perteneciente a la familia de los analogos de la 15-deoxiespergualina.
PCT/FR1996/000203 WO1996024579A1 (fr) 1995-02-10 1996-02-07 Analogues de la 15-deoxyspergualine, leur utilisation en therapeutique et leur procede de preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9509884A FR2737891B1 (fr) 1995-08-17 1995-08-17 Analogues chiraux de la 15-deoxyspergualine, procede de preparation et utilisation en therapeutique

Publications (2)

Publication Number Publication Date
FR2737891A1 FR2737891A1 (fr) 1997-02-21
FR2737891B1 true FR2737891B1 (fr) 1997-10-24

Family

ID=9481968

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9509884A Expired - Fee Related FR2737891B1 (fr) 1995-02-10 1995-08-17 Analogues chiraux de la 15-deoxyspergualine, procede de preparation et utilisation en therapeutique

Country Status (1)

Country Link
FR (1) FR2737891B1 (fr)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5942356A (ja) * 1982-09-02 1984-03-08 Microbial Chem Res Found スパガリン関連化合物およびその製造法
US4525299A (en) * 1983-05-10 1985-06-25 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai (-)-15-Deoxyspergualin, process for the preparation thereof, and intermediate of the same
JPS61129119A (ja) * 1984-11-13 1986-06-17 Microbial Chem Res Found 新規免疫抑制剤

Also Published As

Publication number Publication date
FR2737891A1 (fr) 1997-02-21

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TP Transmission of property
ST Notification of lapse