FR2716451B1 - Analogues de la 15-déoxyspergualine, leur procédé de préparation et leur utilisation en thérapeutique. - Google Patents

Analogues de la 15-déoxyspergualine, leur procédé de préparation et leur utilisation en thérapeutique.

Info

Publication number
FR2716451B1
FR2716451B1 FR9402125A FR9402125A FR2716451B1 FR 2716451 B1 FR2716451 B1 FR 2716451B1 FR 9402125 A FR9402125 A FR 9402125A FR 9402125 A FR9402125 A FR 9402125A FR 2716451 B1 FR2716451 B1 FR 2716451B1
Authority
FR
France
Prior art keywords
deoxyspergualine
analogs
therapy
preparation process
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9402125A
Other languages
English (en)
Other versions
FR2716451A1 (fr
Inventor
Patrice Renaut
Luc Lebreton
Patrick Dutartre
Philippe Derrepas
Soth Samreth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fournier Industrie et Sante SAS
Original Assignee
Fournier Industrie et Sante SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fournier Industrie et Sante SAS filed Critical Fournier Industrie et Sante SAS
Priority to FR9402125A priority Critical patent/FR2716451B1/fr
Priority to FR9406706A priority patent/FR2716452B1/fr
Priority to DK94403019.6T priority patent/DK0669316T3/da
Priority to EP94403019A priority patent/EP0669316B1/fr
Priority to AT94403019T priority patent/ATE156117T1/de
Priority to DE69404624T priority patent/DE69404624T2/de
Priority to ES94403019T priority patent/ES2106480T3/es
Priority to AU10288/95A priority patent/AU691847B2/en
Priority to ZA95623A priority patent/ZA95623B/xx
Priority to NZ270449A priority patent/NZ270449A/en
Priority to FI950728A priority patent/FI950728A/fi
Priority to UA95028166A priority patent/UA37217C2/uk
Priority to NO950664A priority patent/NO302816B1/no
Priority to CNB951021621A priority patent/CN1148378C/zh
Priority to CA002143216A priority patent/CA2143216C/fr
Priority to SK247-95A priority patent/SK281058B6/sk
Priority to JP7035079A priority patent/JP2874839B2/ja
Priority to HU9500556A priority patent/HUT70958A/hu
Priority to RU95102479A priority patent/RU2113431C1/ru
Priority to US08/393,330 priority patent/US5637613A/en
Priority to TW084101713A priority patent/TW317562B/zh
Priority to KR1019950003654A priority patent/KR100188991B1/ko
Priority to CZ1995502A priority patent/CZ287985B6/cs
Publication of FR2716451A1 publication Critical patent/FR2716451A1/fr
Application granted granted Critical
Publication of FR2716451B1 publication Critical patent/FR2716451B1/fr
Priority to GR970402798T priority patent/GR3025164T3/el
Priority to HK97102082A priority patent/HK1000489A1/xx
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/12—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR9402125A 1994-02-24 1994-02-24 Analogues de la 15-déoxyspergualine, leur procédé de préparation et leur utilisation en thérapeutique. Expired - Fee Related FR2716451B1 (fr)

Priority Applications (25)

Application Number Priority Date Filing Date Title
FR9402125A FR2716451B1 (fr) 1994-02-24 1994-02-24 Analogues de la 15-déoxyspergualine, leur procédé de préparation et leur utilisation en thérapeutique.
FR9406706A FR2716452B1 (fr) 1994-02-24 1994-06-01 Analogues de la 15-déoxyspergualine, leur procédé de préparation et leur utilisation en thérapeutique.
EP94403019A EP0669316B1 (fr) 1994-02-24 1994-12-26 Analogues de la 15-déoxyspergualine, leur procédé de préparation et leur utilisation en tant qu'agents immunosuppresseurs
AT94403019T ATE156117T1 (de) 1994-02-24 1994-12-26 15-deoxyspergualine-analoge, verfahren in ihrer herstellung und ihre verwendung als immunosuppressiva
DK94403019.6T DK0669316T3 (da) 1994-02-24 1994-12-26 Analoge til 15-deoxyspergualin, metode til deres fremstilling og deres anvendelse som immunoundertrykkende midler
DE69404624T DE69404624T2 (de) 1994-02-24 1994-12-26 15-Deoxyspergualine-Analoge, Verfahren in ihrer Herstellung und ihre Verwendung als Immunosuppressiva
ES94403019T ES2106480T3 (es) 1994-02-24 1994-12-26 Un compuesto perteneciente a la familia de los analogos de la 15-deoxi-espergualina, su procedimiento de preparacion y su utilizacion en terapeutica.
AU10288/95A AU691847B2 (en) 1994-02-24 1995-01-20 15-deoxyspergualin analogs, their method of preparation and their use in therapeutics
ZA95623A ZA95623B (en) 1994-02-24 1995-01-26 15-deoxyspergualin analogs their method of preparation and their use in therapeutics
NZ270449A NZ270449A (en) 1994-02-24 1995-02-03 15-deoxyspergualin analogues medicaments thereof
UA95028166A UA37217C2 (uk) 1994-02-24 1995-02-17 Аналоги 15-дезоксиспергуаліну, спосіб їх одержання, фармацевтична композиція та проміжні сполуки
FI950728A FI950728A (fi) 1994-02-24 1995-02-17 15-deoksispergualiinianalogit, menetelmä niiden valmistamiseksi ja niiden käyttö lääkinnässä
NO950664A NO302816B1 (no) 1994-02-24 1995-02-22 15-deoksyspergualinanaloger og deres anvendelse, samt mellomprodukt for fremstilling derav
CNB951021621A CN1148378C (zh) 1994-02-24 1995-02-22 15-脱氧精胍林类似物、其制备方法及其治疗应用
CA002143216A CA2143216C (fr) 1994-02-24 1995-02-22 Analogues de la 15-deoxyspergualine, leur preparation et leur utilisation therapeutique
JP7035079A JP2874839B2 (ja) 1994-02-24 1995-02-23 １５−デオキシスペルグアリンアナローグ、その製造方法および治療用としての用途
HU9500556A HUT70958A (en) 1994-02-24 1995-02-23 15-deoxy-spergualin analogs, their intermediates process for producing them and use of them for producing pharmaceutical compositions
RU95102479A RU2113431C1 (ru) 1994-02-24 1995-02-23 Аналоги 15-дезоксиспергуалина, способ их получения, способ получения промежуточных соединений (варианты), аминозащищенные соединения в качестве промежуточных соединений и фармацевтическая композиция на основе аналогов 15-дезоксиспергуалина
US08/393,330 US5637613A (en) 1994-02-24 1995-02-23 15-deoxyspergualin analogs, their method of preparation and their use in therapeutics
SK247-95A SK281058B6 (sk) 1994-02-24 1995-02-23 Analógy 15-deoxyspergualínu, spôsob ich prípravy, medziprodukt na tento spôsob, terapeutický prípravok obsahujúci tieto analógy a ich použitie v terapii
TW084101713A TW317562B (fr) 1994-02-24 1995-02-24
KR1019950003654A KR100188991B1 (ko) 1994-02-24 1995-02-24 15-데옥시스페르구아린유사체,이들의제조방법및치료학적인용도
CZ1995502A CZ287985B6 (cs) 1994-02-24 1995-02-24 Analog 15-deoxyspergualinu, způsob jeho přípravy, meziprodukt pro tento způsob a použití uvedeného analogu
GR970402798T GR3025164T3 (en) 1994-02-24 1997-10-24 Analogs of 15-déoxyspergualine, process for their preparation and their use as immunosuppressive agents.
HK97102082A HK1000489A1 (en) 1994-02-24 1997-11-04 Analogs of 15- deoxyspergualine process for their preparation and their use as immunosuppressive agents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9402125A FR2716451B1 (fr) 1994-02-24 1994-02-24 Analogues de la 15-déoxyspergualine, leur procédé de préparation et leur utilisation en thérapeutique.

Publications (2)

Publication Number Publication Date
FR2716451A1 FR2716451A1 (fr) 1995-08-25
FR2716451B1 true FR2716451B1 (fr) 1996-04-26

Family

ID=9460393

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9402125A Expired - Fee Related FR2716451B1 (fr) 1994-02-24 1994-02-24 Analogues de la 15-déoxyspergualine, leur procédé de préparation et leur utilisation en thérapeutique.

Country Status (2)

Country Link
FR (1) FR2716451B1 (fr)
ZA (1) ZA95623B (fr)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5942356A (ja) * 1982-09-02 1984-03-08 Microbial Chem Res Found スパガリン関連化合物およびその製造法
JPS61129119A (ja) * 1984-11-13 1986-06-17 Microbial Chem Res Found 新規免疫抑制剤

Also Published As

Publication number Publication date
FR2716451A1 (fr) 1995-08-25
ZA95623B (en) 1995-10-05

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ST Notification of lapse

Effective date: 20071030