FR2721943B1 - Adenovirus comprenant un gene codant pour une superoxyde dismutase - Google Patents

Adenovirus comprenant un gene codant pour une superoxyde dismutase

Info

Publication number
FR2721943B1
FR2721943B1 FR9408029A FR9408029A FR2721943B1 FR 2721943 B1 FR2721943 B1 FR 2721943B1 FR 9408029 A FR9408029 A FR 9408029A FR 9408029 A FR9408029 A FR 9408029A FR 2721943 B1 FR2721943 B1 FR 2721943B1
Authority
FR
France
Prior art keywords
adenovirus
gene encoding
superoxide dismutase
dismutase
superoxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9408029A
Other languages
English (en)
Other versions
FR2721943A1 (fr
Inventor
Martine Barkats
Jacques Mallet
Michel Perricaudet
Frederic Revah
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Institut Gustave Roussy (IGR)
Aventis Pharma SA
Original Assignee
Centre National de la Recherche Scientifique CNRS
Rhone Poulenc Rorer SA
Institut Gustave Roussy (IGR)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, Rhone Poulenc Rorer SA, Institut Gustave Roussy (IGR) filed Critical Centre National de la Recherche Scientifique CNRS
Priority to FR9408029A priority Critical patent/FR2721943B1/fr
Priority to IL11427395A priority patent/IL114273A0/xx
Priority to ZA955289A priority patent/ZA955289B/xx
Priority to AU28905/95A priority patent/AU2890595A/en
Priority to JP8502873A priority patent/JPH10505485A/ja
Priority to MX9606327A priority patent/MX9606327A/es
Priority to EP95924371A priority patent/EP0774008A1/fr
Priority to US08/765,026 priority patent/US20030059455A1/en
Priority to PCT/FR1995/000854 priority patent/WO1996000790A1/fr
Priority to CA002190883A priority patent/CA2190883A1/fr
Publication of FR2721943A1 publication Critical patent/FR2721943A1/fr
Application granted granted Critical
Publication of FR2721943B1 publication Critical patent/FR2721943B1/fr
Priority to NO965406A priority patent/NO965406D0/no
Priority to FI965231A priority patent/FI965231A/fi
Priority to US11/153,317 priority patent/US20050244381A1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44—Oxidoreductases (1)
    • A61K38/446—Superoxide dismutase (1.15)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0089—Oxidoreductases (1.) acting on superoxide as acceptor (1.15)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Botany (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
FR9408029A 1994-06-29 1994-06-29 Adenovirus comprenant un gene codant pour une superoxyde dismutase Expired - Fee Related FR2721943B1 (fr)

Priority Applications (13)

Application Number Priority Date Filing Date Title
FR9408029A FR2721943B1 (fr) 1994-06-29 1994-06-29 Adenovirus comprenant un gene codant pour une superoxyde dismutase
IL11427395A IL114273A0 (en) 1994-06-29 1995-06-22 Adenovirus which comprises a sequence encoding a superoxide dismutase
ZA955289A ZA955289B (en) 1994-06-29 1995-06-26 Adenovirus which comprises a sequence encoding a superoxide dismutase
EP95924371A EP0774008A1 (fr) 1994-06-29 1995-06-27 Adenovirus comprenant un gene codant pour une superoxyde dismutase
JP8502873A JPH10505485A (ja) 1994-06-29 1995-06-27 スーパーオキシドジスムターゼをコードする遺伝子を含むアデノウイルス
MX9606327A MX9606327A (es) 1994-06-29 1995-06-27 Adenovirus que comprende un gen que codifica para un superoxido dismutasa.
AU28905/95A AU2890595A (en) 1994-06-29 1995-06-27 Adenovirus including a gene coding for a superoxide dismutase
US08/765,026 US20030059455A1 (en) 1994-06-29 1995-06-27 Adenovirus including a gene coding for a superoxide dismutase
PCT/FR1995/000854 WO1996000790A1 (fr) 1994-06-29 1995-06-27 Adenovirus comprenant un gene codant pour une superoxyde dismutase
CA002190883A CA2190883A1 (fr) 1994-06-29 1995-06-27 Adenovirus comprenant un gene codant pour une superoxyde dismutase
NO965406A NO965406D0 (no) 1994-06-29 1996-12-16 Adenovirus omfattende et gen som koder for en peroksyddismutase
FI965231A FI965231A (fi) 1994-06-29 1996-12-27 Adenovirus, joka sisältää superoksidismutaasia koodittavan geenin
US11/153,317 US20050244381A1 (en) 1994-06-29 2005-06-16 Adenovirus including a gene coding for a superoxide dismutase

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9408029A FR2721943B1 (fr) 1994-06-29 1994-06-29 Adenovirus comprenant un gene codant pour une superoxyde dismutase

Publications (2)

Publication Number Publication Date
FR2721943A1 FR2721943A1 (fr) 1996-01-05
FR2721943B1 true FR2721943B1 (fr) 1996-08-02

Family

ID=9464803

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9408029A Expired - Fee Related FR2721943B1 (fr) 1994-06-29 1994-06-29 Adenovirus comprenant un gene codant pour une superoxyde dismutase

Country Status (12)

Country Link
US (2) US20030059455A1 (fr)
EP (1) EP0774008A1 (fr)
JP (1) JPH10505485A (fr)
AU (1) AU2890595A (fr)
CA (1) CA2190883A1 (fr)
FI (1) FI965231A (fr)
FR (1) FR2721943B1 (fr)
IL (1) IL114273A0 (fr)
MX (1) MX9606327A (fr)
NO (1) NO965406D0 (fr)
WO (1) WO1996000790A1 (fr)
ZA (1) ZA955289B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5846782A (en) 1995-11-28 1998-12-08 Genvec, Inc. Targeting adenovirus with use of constrained peptide motifs
US6465253B1 (en) 1994-09-08 2002-10-15 Genvec, Inc. Vectors and methods for gene transfer to cells
US6127525A (en) * 1995-02-21 2000-10-03 Cornell Research Foundation, Inc. Chimeric adenoviral coat protein and methods of using same
US5770442A (en) * 1995-02-21 1998-06-23 Cornell Research Foundation, Inc. Chimeric adenoviral fiber protein and methods of using same
ES2333425T5 (es) 1995-06-15 2012-08-28 Crucell Holland B.V. Sistemas de empaquetado para adenovirus recombinante humano destinados a terapia génica
AU8671798A (en) * 1997-07-30 1999-02-22 Betagene, Inc. Methods and compositions relating to no-mediated cytotoxicity
US6171856B1 (en) 1997-07-30 2001-01-09 Board Of Regents, The University Of Texas System Methods and compositions relating to no-mediated cytotoxicity
US20030017138A1 (en) 1998-07-08 2003-01-23 Menzo Havenga Chimeric adenoviruses
US6929946B1 (en) 1998-11-20 2005-08-16 Crucell Holland B.V. Gene delivery vectors provided with a tissue tropism for smooth muscle cells, and/or endothelial cells
US6913922B1 (en) 1999-05-18 2005-07-05 Crucell Holland B.V. Serotype of adenovirus and uses thereof
US20050232900A1 (en) * 1999-05-18 2005-10-20 Crucell Holland B.V. Serotype of adenovirus and uses thereof
US6492169B1 (en) 1999-05-18 2002-12-10 Crucell Holland, B.V. Complementing cell lines
DE60138403D1 (de) 2000-09-26 2009-05-28 Crucell Holland Bv Adenovirale vektoren für die übertragung von genen in zellen der skelettmuskulatur oder myoblasten
FI20010898A0 (fi) * 2001-04-30 2001-04-30 Ylae Herttuala Seppo Ekstrasellulaarinen superoksididismutaasi (EC-SOD) geeniterapia restenoosoin ehkäisemiseksi
SI1497438T1 (sl) * 2002-04-25 2010-03-31 Crucell Holland Bv Sredstva in postopki za pripravo adenovirusnih vektorjev
EP1499344A1 (fr) * 2002-04-30 2005-01-26 FIT Biotech Oyj Plc Dispositif medical
US20050036988A1 (en) * 2003-05-28 2005-02-17 Ruian Xu Compositions and methods for preventing and treating liver cirrhosis
BR112012007137A2 (pt) 2009-09-30 2015-09-15 Harvard College metodos para modulacao da autofagia por meio da modulacao de produtos genicos inibidores da autofagia
US11439690B2 (en) 2013-02-07 2022-09-13 The Cleveland Clinic Foundation Methods of treating spinal cord injury
CN109833468A (zh) * 2019-03-21 2019-06-04 吉林大学 一种金属有机框架-超氧化物歧化酶组装体、制备方法及其在制备治疗帕金森药物中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE69618T1 (de) * 1983-10-03 1991-12-15 Chiron Corp Klonieren von superoxid-dismutase und expression in mikroorganismen.
EP0213628A3 (fr) * 1985-09-03 1988-09-21 Yeda Research And Development Company, Ltd. Expression de superoxyde-dismutase dans des cellules eucaryotes
US5082670A (en) * 1988-12-15 1992-01-21 The Regents Of The University Of California Method of grafting genetically modified cells to treat defects, disease or damage or the central nervous system

Also Published As

Publication number Publication date
ZA955289B (en) 1996-01-31
MX9606327A (es) 1997-03-29
NO965406L (no) 1996-12-16
FI965231A0 (fi) 1996-12-27
EP0774008A1 (fr) 1997-05-21
JPH10505485A (ja) 1998-06-02
FR2721943A1 (fr) 1996-01-05
US20030059455A1 (en) 2003-03-27
US20050244381A1 (en) 2005-11-03
NO965406D0 (no) 1996-12-16
CA2190883A1 (fr) 1996-01-11
WO1996000790A1 (fr) 1996-01-11
FI965231A (fi) 1996-12-27
AU2890595A (en) 1996-01-25
IL114273A0 (en) 1995-10-31

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Effective date: 20070228