FR2706897A1 - - Google Patents

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Publication number
FR2706897A1
FR2706897A1 FR9407523A FR9407523A FR2706897A1 FR 2706897 A1 FR2706897 A1 FR 2706897A1 FR 9407523 A FR9407523 A FR 9407523A FR 9407523 A FR9407523 A FR 9407523A FR 2706897 A1 FR2706897 A1 FR 2706897A1
Authority
FR
France
Prior art keywords
group
alkyl
hydrogen
methyl
cis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR9407523A
Other languages
English (en)
French (fr)
Other versions
FR2706897B1 (fi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorio Guidotti SpA
Original Assignee
Laboratorio Guidotti SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorio Guidotti SpA filed Critical Laboratorio Guidotti SpA
Publication of FR2706897A1 publication Critical patent/FR2706897A1/fr
Application granted granted Critical
Publication of FR2706897B1 publication Critical patent/FR2706897B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74—Adamantanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR9407523A 1993-06-21 1994-06-20 Expired - Fee Related FR2706897B1 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT93MI001329A IT1264860B1 (it) 1993-06-21 1993-06-21 Derivati di acidi cis- e trans-2(((2-(isdrossiammino)-2-ossoetil)- alchilammino)carbonil)cicloesancarbossilici

Publications (2)

Publication Number Publication Date
FR2706897A1 true FR2706897A1 (fi) 1994-12-30
FR2706897B1 FR2706897B1 (fi) 1996-01-26

Family

ID=11366439

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9407523A Expired - Fee Related FR2706897B1 (fi) 1993-06-21 1994-06-20

Country Status (4)

Country Link
DE (1) DE4421515A1 (fi)
FR (1) FR2706897B1 (fi)
GB (1) GB2279345A (fi)
IT (1) IT1264860B1 (fi)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639746A (en) * 1994-12-29 1997-06-17 The Procter & Gamble Company Hydroxamic acid-containing inhibitors of matrix metalloproteases
GB0509223D0 (en) * 2005-05-05 2005-06-15 Chroma Therapeutics Ltd Enzyme inhibitors
JP7197880B2 (ja) * 2017-10-19 2022-12-28 学校法人 名城大学 エステル化剤及びその利用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5095137A (en) * 1988-04-02 1992-03-10 Laboratori Guidotti Spa Amides of cyclomethylen-1,2-bicarboxylic acids having therapeutical activity

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1252708B (it) * 1991-12-23 1995-06-26 Guidotti & C Spa Labor Sali stabili dell'acido (+)-(1r,2s)-2((n-(2-idrossilammino-2-ossoetil)-n-metilammino)carbonil)cicloesan-1-carbossilico,ad attivita' ace inibitrice, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono.

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5095137A (en) * 1988-04-02 1992-03-10 Laboratori Guidotti Spa Amides of cyclomethylen-1,2-bicarboxylic acids having therapeutical activity

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
TURBANTI L ET AL: "1,2-Cyclomethylencarboxylic monoamide hydroxamic derivatives. A novel class of non-amino acid angiotensin converting enzyme inhibitors", J. MED. CHEM. (JMCMAR,00222623);93; VOL.36 (6); PP.699-707, LAB. GUIDOTTI S.P.A.;PISA; 56122; ITALY (IT) *

Also Published As

Publication number Publication date
DE4421515A1 (de) 1994-12-22
ITMI931329A1 (it) 1994-12-21
FR2706897B1 (fi) 1996-01-26
GB2279345A (en) 1995-01-04
GB9412367D0 (en) 1994-08-10
ITMI931329A0 (it) 1993-06-21
IT1264860B1 (it) 1996-10-17

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