FR2681875A1 - Nouvelles molecules de adn recombinants contenant la partie codante d'une chaine vb17 du recepteur pour l'antigene des cellules t, procede de preparation, anticorps et medicaments les renfermant. - Google Patents

Nouvelles molecules de adn recombinants contenant la partie codante d'une chaine vb17 du recepteur pour l'antigene des cellules t, procede de preparation, anticorps et medicaments les renfermant. Download PDF

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Publication number
FR2681875A1
FR2681875A1 FR9112148A FR9112148A FR2681875A1 FR 2681875 A1 FR2681875 A1 FR 2681875A1 FR 9112148 A FR9112148 A FR 9112148A FR 9112148 A FR9112148 A FR 9112148A FR 2681875 A1 FR2681875 A1 FR 2681875A1
Authority
FR
France
Prior art keywords
sequence
chain
antibodies
recombinant dna
murine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR9112148A
Other languages
English (en)
French (fr)
Other versions
FR2681875B1 (OSRAM
Inventor
Romagne Francois
Agthoven Van Andre
Malissen Bernard
Besnardeau Lydia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IMMUNOTECH SA
Immunotech SAS
Original Assignee
IMMUNOTECH SA
Immunotech SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IMMUNOTECH SA, Immunotech SAS filed Critical IMMUNOTECH SA
Priority to FR9112148A priority Critical patent/FR2681875A1/fr
Priority to EP92430022A priority patent/EP0534878A1/fr
Priority to CA002079197A priority patent/CA2079197A1/fr
Priority to JP4258117A priority patent/JPH05276956A/ja
Publication of FR2681875A1 publication Critical patent/FR2681875A1/fr
Application granted granted Critical
Publication of FR2681875B1 publication Critical patent/FR2681875B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
FR9112148A 1991-09-26 1991-09-26 Nouvelles molecules de adn recombinants contenant la partie codante d'une chaine vb17 du recepteur pour l'antigene des cellules t, procede de preparation, anticorps et medicaments les renfermant. Granted FR2681875A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
FR9112148A FR2681875A1 (fr) 1991-09-26 1991-09-26 Nouvelles molecules de adn recombinants contenant la partie codante d'une chaine vb17 du recepteur pour l'antigene des cellules t, procede de preparation, anticorps et medicaments les renfermant.
EP92430022A EP0534878A1 (fr) 1991-09-26 1992-09-24 Molécules d'ADN recombinants contenant la partie codante d'une chaîne Vbêta17 du récepteur pour l'antigène des cellules T et leurs utilisations
CA002079197A CA2079197A1 (fr) 1991-09-26 1992-09-25 Nouvelles molecules de adn recombinants contenant la partie codante d'une chaine vbeta17 du recepteur pour l'antigene des cellules t, procede de preparation, anticorps et medicaments les renfermant
JP4258117A JPH05276956A (ja) 1991-09-26 1992-09-28 ヒトＴ−細胞抗原レセプターＶβ１７鎖のコード部分を含む新規組換えＤＮＡ分子、それらの調製法、抗体及びそれらを含む薬剤

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9112148A FR2681875A1 (fr) 1991-09-26 1991-09-26 Nouvelles molecules de adn recombinants contenant la partie codante d'une chaine vb17 du recepteur pour l'antigene des cellules t, procede de preparation, anticorps et medicaments les renfermant.

Publications (2)

Publication Number Publication Date
FR2681875A1 true FR2681875A1 (fr) 1993-04-02
FR2681875B1 FR2681875B1 (OSRAM) 1995-01-06

Family

ID=9417529

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9112148A Granted FR2681875A1 (fr) 1991-09-26 1991-09-26 Nouvelles molecules de adn recombinants contenant la partie codante d'une chaine vb17 du recepteur pour l'antigene des cellules t, procede de preparation, anticorps et medicaments les renfermant.

Country Status (4)

Country Link
EP (1) EP0534878A1 (OSRAM)
JP (1) JPH05276956A (OSRAM)
CA (1) CA2079197A1 (OSRAM)
FR (1) FR2681875A1 (OSRAM)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113874400B (zh) 2019-03-11 2025-02-07 詹森生物科技公司 抗Vβ17/抗CD123双特异性抗体
AU2021339754A1 (en) * 2020-09-11 2023-05-25 Janssen Biotech, Inc. Methods and compositions for modulating beta chain mediated immunity

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0340793A2 (en) * 1988-05-04 1989-11-08 Yeda Research And Development Company Limited Endowing cells with antibody specificity
WO1991010438A1 (en) * 1990-01-12 1991-07-25 Protein Design Labs, Inc. Soluble t-cell antigen receptor chimeric antigens

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0340793A2 (en) * 1988-05-04 1989-11-08 Yeda Research And Development Company Limited Endowing cells with antibody specificity
WO1991010438A1 (en) * 1990-01-12 1991-07-25 Protein Design Labs, Inc. Soluble t-cell antigen receptor chimeric antigens

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
EUROPEAN JOURNAL OF IMMUNOLOGY vol. 17, 1987, VCH VERLAGSGESELLSCHAFT, DEUTSCHLAND pages 375 - 383; KIMURA, N. ET AL.: 'Sequences and repertoire of the human T cell receptor alpha and beta chain variable region genes in thymocytes' *
IMMUNOLOGICAL REVIEWS no. 101, 1988, COPENHAGEN, DK pages 149 - 172; WILSON, R.K., LAI, E., CONCANNON, P., BARTH, R.K., HOOD, L.E.: 'Structure, Organisation and polymorphism of murine and human T-cell receptor alpha and beta chain gene families.' *

Also Published As

Publication number Publication date
EP0534878A1 (fr) 1993-03-31
CA2079197A1 (fr) 1993-03-27
JPH05276956A (ja) 1993-10-26
FR2681875B1 (OSRAM) 1995-01-06

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