FR2680520B1 - Procede de detection de nouvelles regions hypervariables dans une sequence d'adn, sequences de nucleotides constituant des sondes d'hybridation et leur application biologique. - Google Patents

Procede de detection de nouvelles regions hypervariables dans une sequence d'adn, sequences de nucleotides constituant des sondes d'hybridation et leur application biologique.

Info

Publication number
FR2680520B1
FR2680520B1 FR9110516A FR9110516A FR2680520B1 FR 2680520 B1 FR2680520 B1 FR 2680520B1 FR 9110516 A FR9110516 A FR 9110516A FR 9110516 A FR9110516 A FR 9110516A FR 2680520 B1 FR2680520 B1 FR 2680520B1
Authority
FR
France
Prior art keywords
detection
dna sequence
nucleotide sequences
hypervariable regions
hybridization probes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9110516A
Other languages
English (en)
Other versions
FR2680520A1 (fr
Inventor
Vergnaud Gilles
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Direction General pour lArmement DGA
Original Assignee
Direction General pour lArmement DGA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Direction General pour lArmement DGA filed Critical Direction General pour lArmement DGA
Priority to FR9110516A priority Critical patent/FR2680520B1/fr
Publication of FR2680520A1 publication Critical patent/FR2680520A1/fr
Priority to US08/303,004 priority patent/US5556955A/en
Application granted granted Critical
Publication of FR2680520B1 publication Critical patent/FR2680520B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
FR9110516A 1991-08-22 1991-08-22 Procede de detection de nouvelles regions hypervariables dans une sequence d'adn, sequences de nucleotides constituant des sondes d'hybridation et leur application biologique. Expired - Lifetime FR2680520B1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR9110516A FR2680520B1 (fr) 1991-08-22 1991-08-22 Procede de detection de nouvelles regions hypervariables dans une sequence d'adn, sequences de nucleotides constituant des sondes d'hybridation et leur application biologique.
US08/303,004 US5556955A (en) 1991-08-22 1994-09-08 Process for detection of new polymorphic loci in a DNA sequence, nucleotide sequences forming hybridization probes and their applications

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9110516A FR2680520B1 (fr) 1991-08-22 1991-08-22 Procede de detection de nouvelles regions hypervariables dans une sequence d'adn, sequences de nucleotides constituant des sondes d'hybridation et leur application biologique.

Publications (2)

Publication Number Publication Date
FR2680520A1 FR2680520A1 (fr) 1993-02-26
FR2680520B1 true FR2680520B1 (fr) 1995-09-22

Family

ID=9416339

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9110516A Expired - Lifetime FR2680520B1 (fr) 1991-08-22 1991-08-22 Procede de detection de nouvelles regions hypervariables dans une sequence d'adn, sequences de nucleotides constituant des sondes d'hybridation et leur application biologique.

Country Status (2)

Country Link
US (1) US5556955A (fr)
FR (1) FR2680520B1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994011531A1 (fr) 1992-11-13 1994-05-26 California Institute Of Biological Research Identification de neoplasmes par detection des insertions et deletions genetiques
US5492808A (en) * 1993-05-05 1996-02-20 The Johns Hopkins University Means for detecting familial colon cancer (FCC)
FR2711672B1 (fr) * 1993-10-29 1995-12-08 France Etat Armement Procédé de sélection et/ou d'obtention de sondes capables de détecter de nouvelles régions à nombre variable de répétitions en tandem, sondes pouvant être ainsi obtenues et leurs utilisations.
GB9326052D0 (en) * 1993-12-21 1994-02-23 Zeneca Ltd Sequences
US5635351A (en) * 1995-03-14 1997-06-03 The Regents Of The University Of California Genetic gain and loss in gliomas
AU4174397A (en) 1996-08-30 1998-03-19 Life Technologies, Inc. Methods for identification and isolation of specific nucleotide sequences in cdna and genomic dna
US6306588B1 (en) 1997-02-07 2001-10-23 Invitrogen Corporation Polymerases for analyzing or typing polymorphic nucleic acid fragments and uses thereof
AU2789299A (en) * 1998-02-26 1999-09-15 Genomics Collaborative, Inc. Unique identifier for biological samples
JP2002543795A (ja) * 1999-05-12 2002-12-24 インビトロゲン・コーポレーション 核酸合成の感度および特異性の増大のための組成物および方法
US6420112B2 (en) * 1999-07-21 2002-07-16 The Regents Of The University Of California DNA attachment to support structures
US9361427B2 (en) 2011-02-01 2016-06-07 The Regents Of The University Of California Scar-less multi-part DNA assembly design automation
GB201116131D0 (en) * 2011-09-19 2011-11-02 Epistem Ltd Probe

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IS1355B6 (is) * 1984-11-12 1989-04-19 Lister Institute Of Preventive Medicine Fjölkjarna kannar
GB8606719D0 (en) * 1986-03-19 1986-04-23 Lister Preventive Med Genetic probes
US4987066A (en) * 1986-11-07 1991-01-22 Max Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Process for the detection of restriction fragment length polymorphisms in eukaryotic genomes
DE68929070T2 (de) * 1988-02-18 2000-05-25 Univ Utah Verwendung von dna-proben mit variabler anzahl von tandem-repetitiven stellen zur genetischen identifizierung
US4963663A (en) * 1988-12-23 1990-10-16 University Of Utah Genetic identification employing DNA probes of variable number tandem repeat loci
IT1230152B (it) * 1988-06-10 1991-10-14 Ici Plc Sequenze di nucleotidi.
US5380645A (en) * 1989-03-16 1995-01-10 The Johns Hopkins University Generalized method for assessment of colorectal carcinoma
WO1991010748A1 (fr) * 1990-01-16 1991-07-25 Collaborative Research, Inc. Sequences d'adn provenant de loci genomiques humains specifiques utiles a l'identification d'individus

Also Published As

Publication number Publication date
FR2680520A1 (fr) 1993-02-26
US5556955A (en) 1996-09-17

Similar Documents

Publication Publication Date Title
FR2694754B1 (fr) Fragments d'ADN de mycobactéries, amorces d'amplification, sondes d'hybridation, réactifs et procédé de détection de détection de mycobactéries.
FR2680520B1 (fr) Procede de detection de nouvelles regions hypervariables dans une sequence d'adn, sequences de nucleotides constituant des sondes d'hybridation et leur application biologique.
MA22905A1 (fr) Nouvelles sequences d'adn .
ES2147180T3 (es) Procedimiento para la deteccion de acidos nucleicos semejantes.
DE69109100D1 (de) Oligonukleotid-analoge.
NO890972D0 (no) Kjemisk regulerbare dna-sekvenser og gener.
DK0525095T4 (da) Hybridiseringsprober afledt fra spacer-regionen mellem 16S og 23S rRNA gener til påvisning af ikke-virale mikroorganismer
ATE244259T1 (de) Verwendungen von fluoreszierenden n-nukleosiden und dessen analogen
FR2709310B1 (fr) Fragment nucléotidique de l'ARN ribosomique 23S de mycobactéries, sondes et amorces dérivées, réactif et procédé de détection.
DE69332666T2 (de) Verfahren zur einfachen nukleotid-primer-verlängerung zum nachweis spezifischer allele und dafür geeigneter kit
DE69815370D1 (de) Fluoreszend-konjugaten von nukleosiden und von nukleotiden, ihrer verfahren zur herstellung und ihrer verwendungen
FR2687168B1 (fr) Fragment de l'adn genomique de streptococcus pneumoniae, sonde d'hybridation, amorce d'amplification, reactif et procede de detection de streptococcus pneumoniae.
ATE144557T1 (de) Nucleinsäure-proben und verfahren zum nachweis von giardia lamblia
FR2599743B1 (fr) Fragment d'adn comprenant au moins une partie d'un gene de resistance a l'erythromycine, son procede d'obtention et ses applications biochimiques
FR2733755B1 (fr) Fragment nucleotidique de l'arn ribosomique 16s de corynebacteries, sondes et amorces derivees, reactif et procede de detection
FR2603047B1 (fr) Sonde d'hybridation pour la detection de sequences nucleotidiques polymorphes contenues dans un echantillon d'adn humain ou animal, procede de detection de sequences d'adn polymorphes utilisant une telle sonde, ses applications biologiques
FR2648476B1 (fr) Acide nucleique et oligonucleotide en derivant, constituant des sondes nucleotidiques specifiques de plasmodium falciparum, et leur application pour la detection par hybridation de l'adn de plasmodium falciparum
FR2733754B1 (fr) Fragment de l'adn genomique de clavibacter michiganensis, sonde d'hybridation, amorce d'amplification, reactif et procede de detection de clavibacter michiganensis
FR2699190B1 (fr) Procédé pour favoriser la différenciation de cellules, substances protéiques possédant une activité de transfert de lipides, compositions les contenant, séquences d'ADN et sondes d'oligonucléotides correspondantes.
FR2718461B1 (fr) Procédé de détection d'un site de restriction dans une séquence d'ADN.
ATE187500T1 (de) Nachweis von yersinia intermedia
FI914293A0 (fi) Foerfarande foer kemisk syntes av oligonukleotider.
FR2668162B1 (fr) Fragments d'adn, procede et coffret de diagnostic pour la detection des porteurs de la mutation delta-f-508 responsable de la mucoviscidose.
EP0756008A3 (fr) Substrat pour la détection de 5-C-ADN méthyltransférase de mammifères
FR2673953B1 (fr) Procede de sequencage non radioactif d'adn.

Legal Events

Date Code Title Description
CL Concession to grant licences
CL Concession to grant licences

Free format text: CORRECTION

CL Concession to grant licences
CL Concession to grant licences