FR2675694A1 - Systeme d'apport osteogenique pour facteurs de croissance morphogenetiques et procede pour preparer un tel systeme. - Google Patents

Systeme d'apport osteogenique pour facteurs de croissance morphogenetiques et procede pour preparer un tel systeme. Download PDF

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Publication number
FR2675694A1
FR2675694A1 FR9205249A FR9205249A FR2675694A1 FR 2675694 A1 FR2675694 A1 FR 2675694A1 FR 9205249 A FR9205249 A FR 9205249A FR 9205249 A FR9205249 A FR 9205249A FR 2675694 A1 FR2675694 A1 FR 2675694A1
Authority
FR
France
Prior art keywords
biologically active
delivery system
bone
porous
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR9205249A
Other languages
English (en)
French (fr)
Other versions
FR2675694B1 (enExample
Inventor
Ripamonti Ugo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
South African Medical Research Council
Original Assignee
South African Medical Research Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by South African Medical Research Council filed Critical South African Medical Research Council
Publication of FR2675694A1 publication Critical patent/FR2675694A1/fr
Application granted granted Critical
Publication of FR2675694B1 publication Critical patent/FR2675694B1/fr
Granted legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/51Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1875Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56Porous materials, e.g. foams or sponges
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/901Method of manufacturing prosthetic device
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/915Method or apparatus for preparing biological material

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Transplantation (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dispersion Chemistry (AREA)
  • Toxicology (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR9205249A 1991-04-29 1992-04-29 Systeme d'apport osteogenique pour facteurs de croissance morphogenetiques et procede pour preparer un tel systeme. Granted FR2675694A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ZA913225 1991-04-29

Publications (2)

Publication Number Publication Date
FR2675694A1 true FR2675694A1 (fr) 1992-10-30
FR2675694B1 FR2675694B1 (enExample) 1995-05-24

Family

ID=25580652

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9205249A Granted FR2675694A1 (fr) 1991-04-29 1992-04-29 Systeme d'apport osteogenique pour facteurs de croissance morphogenetiques et procede pour preparer un tel systeme.

Country Status (5)

Country Link
US (2) US5443531A (enExample)
DE (1) DE4214117A1 (enExample)
FR (1) FR2675694A1 (enExample)
GB (1) GB2255907B (enExample)
ZA (1) ZA923086B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0616814A1 (en) * 1993-03-26 1994-09-28 Bristol-Myers Squibb Company Compositions for controlled release of biologically active TGF - beta
US8663337B2 (en) 2007-06-18 2014-03-04 Zimmer, Inc. Process for forming a ceramic layer

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2551185C (en) 1994-03-28 2007-10-30 Sdgi Holdings, Inc. Apparatus and method for anterior spinal stabilization
US5817327A (en) * 1994-07-27 1998-10-06 The Trustees Of The University Of Pennsylvania Incorporation of biologically active molecules into bioactive glasses
US5591453A (en) * 1994-07-27 1997-01-07 The Trustees Of The University Of Pennsylvania Incorporation of biologically active molecules into bioactive glasses
US6352972B1 (en) * 1995-06-06 2002-03-05 Marcel E. Nimni Bone morphogenetic proteins and their use in bone growth
US20020114795A1 (en) * 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
US7175336B2 (en) * 2001-01-26 2007-02-13 Depuy Acromed, Inc. Graft delivery system
KR20040053137A (ko) * 2001-09-24 2004-06-23 베리겐 아게 자가 성장 인자 칵테일 조성물, 이의 제조 방법 및 용도
US7718616B2 (en) 2006-12-21 2010-05-18 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
WO2012068135A1 (en) 2010-11-15 2012-05-24 Zimmer Orthobiologics, Inc. Bone void fillers
WO2016044072A1 (en) 2014-09-18 2016-03-24 Mayo Foundation For Medical Education And Research Soft tissue cutting device and methods of use
US10864055B2 (en) 2017-10-13 2020-12-15 Sonex Health, Inc. Tray for a soft tissue cutting device and methods of use
US11937845B2 (en) 2019-01-11 2024-03-26 Mayo Foundation For Medical Education And Research Micro-invasive surgical device and methods of use
US12426939B2 (en) 2019-05-29 2025-09-30 Mayo Foundation For Medical Education And Research Micro-invasive surgical device and methods of use
US12004767B2 (en) 2021-01-08 2024-06-11 Sonex Health, Inc. Surgical cutting device for ultrasonic guided soft tissue surgery
US12251122B2 (en) 2021-04-30 2025-03-18 Sonex Health, Inc. Cutting device for trigger finger and other soft tissues
USD989961S1 (en) 2021-04-30 2023-06-20 Sonex Health, Inc. Soft tissue cutting device
WO2024044237A1 (en) 2022-08-25 2024-02-29 Sonex Health, Inc. De quervain's treatment device

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4627982A (en) * 1984-07-16 1986-12-09 Collagen Corporation Partially purified bone-inducing factor
EP0271668A1 (de) * 1986-10-22 1988-06-22 Gesellschaft für Biotechnologische Forschung mbH (GBF) Wachstumstimulierendes Material, Herstellungsverfahren und therapeutische Zusammensetzung
WO1989010409A1 (en) * 1988-04-08 1989-11-02 Genetics Institute, Inc. Bone and cartilage inductive compositions
WO1990003733A1 (en) * 1988-10-11 1990-04-19 International Genetic Engineering, Inc. Osteogenic factors
WO1990011366A1 (en) * 1989-03-28 1990-10-04 Genetics Institute, Inc. Osteoinductive compositions
US7720174B2 (en) * 2001-12-21 2010-05-18 Digital Fountain, Inc. Multi-stage code generator and decoder for communication systems

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3929971A (en) * 1973-03-30 1975-12-30 Research Corp Porous biomaterials and method of making same
US4294753A (en) * 1980-08-04 1981-10-13 The Regents Of The University Of California Bone morphogenetic protein process
US4546500A (en) * 1981-05-08 1985-10-15 Massachusetts Institute Of Technology Fabrication of living blood vessels and glandular tissues
US4596574A (en) * 1984-05-14 1986-06-24 The Regents Of The University Of California Biodegradable porous ceramic delivery system for bone morphogenetic protein
NL8501769A (nl) * 1984-10-02 1986-05-01 Imec Interuniversitair Micro E Bipolaire heterojunctie-transistor en werkwijze voor de vervaardiging daarvan.
US5035708A (en) * 1985-06-06 1991-07-30 Thomas Jefferson University Endothelial cell procurement and deposition kit
GB8606468D0 (en) * 1986-03-15 1986-04-23 Sds Biotech Uk Ltd Therapeutic compositions
US5010009A (en) * 1988-08-22 1991-04-23 Commonwealth Scientific & Industrial Research Organisation & Telectronics Pty. Limited Material for cell attachment and growth
US5108436A (en) * 1988-09-29 1992-04-28 Collagen Corporation Implant fixation
JPH0791181B2 (ja) * 1989-12-26 1995-10-04 花王株式会社 浴用剤組成物

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4627982A (en) * 1984-07-16 1986-12-09 Collagen Corporation Partially purified bone-inducing factor
EP0271668A1 (de) * 1986-10-22 1988-06-22 Gesellschaft für Biotechnologische Forschung mbH (GBF) Wachstumstimulierendes Material, Herstellungsverfahren und therapeutische Zusammensetzung
WO1989010409A1 (en) * 1988-04-08 1989-11-02 Genetics Institute, Inc. Bone and cartilage inductive compositions
WO1990003733A1 (en) * 1988-10-11 1990-04-19 International Genetic Engineering, Inc. Osteogenic factors
WO1990011366A1 (en) * 1989-03-28 1990-10-04 Genetics Institute, Inc. Osteoinductive compositions
US7720174B2 (en) * 2001-12-21 2010-05-18 Digital Fountain, Inc. Multi-stage code generator and decoder for communication systems

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH no. 268, Juillet 1991, pages 303 - 312 Y.ORISAKA ET AL. *
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA vol. 81, Janvier 1984, pages 371 - 375 M.R.URIST ET AL. *
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA vol. 84, Octobre 1987, pages 7109 - 7113 T.K.SAMPATH ET AL. DISCUSSION *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0616814A1 (en) * 1993-03-26 1994-09-28 Bristol-Myers Squibb Company Compositions for controlled release of biologically active TGF - beta
US8663337B2 (en) 2007-06-18 2014-03-04 Zimmer, Inc. Process for forming a ceramic layer

Also Published As

Publication number Publication date
GB9209213D0 (en) 1992-06-17
US5443531A (en) 1995-08-22
GB2255907B (en) 1994-12-14
GB2255907A (en) 1992-11-25
DE4214117A1 (de) 1992-11-05
FR2675694B1 (enExample) 1995-05-24
ZA923086B (en) 1993-10-28
US5769895A (en) 1998-06-23

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