FR2648815B1 - Procede stereoselectif nouveau de preparation de dihydrolysergol par hydrogenation - Google Patents
Procede stereoselectif nouveau de preparation de dihydrolysergol par hydrogenationInfo
- Publication number
- FR2648815B1 FR2648815B1 FR909007757A FR9007757A FR2648815B1 FR 2648815 B1 FR2648815 B1 FR 2648815B1 FR 909007757 A FR909007757 A FR 909007757A FR 9007757 A FR9007757 A FR 9007757A FR 2648815 B1 FR2648815 B1 FR 2648815B1
- Authority
- FR
- France
- Prior art keywords
- dihydrolysergol
- hydrogenation
- preparation
- stereoselective process
- new stereoselective
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- UFKTZIXVYHGAES-WDBKCZKBSA-N [(6ar,9r,10ar)-7-methyl-6,6a,8,9,10,10a-hexahydro-4h-indolo[4,3-fg]quinoline-9-yl]methanol Chemical compound C1=CC([C@H]2C[C@@H](CO)CN([C@@H]2C2)C)=C3C2=CNC3=C1 UFKTZIXVYHGAES-WDBKCZKBSA-N 0.000 title 1
- 238000005984 hydrogenation reaction Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 230000000707 stereoselective effect Effects 0.000 title 1
- UFKTZIXVYHGAES-UHFFFAOYSA-N trans-dihydrolysergol Natural products C1=CC(C2CC(CO)CN(C2C2)C)=C3C2=CNC3=C1 UFKTZIXVYHGAES-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU893225A HU203549B (en) | 1989-06-27 | 1989-06-27 | New stereoselektive hydrogenating process for producing dihydro-lisergol |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2648815A1 FR2648815A1 (fr) | 1990-12-28 |
| FR2648815B1 true FR2648815B1 (fr) | 1992-08-14 |
Family
ID=10963194
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR909007757A Expired - Lifetime FR2648815B1 (fr) | 1989-06-27 | 1990-06-21 | Procede stereoselectif nouveau de preparation de dihydrolysergol par hydrogenation |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5097031A (online.php) |
| JP (1) | JPH03128374A (online.php) |
| CA (1) | CA2019407C (online.php) |
| CH (1) | CH680445A5 (online.php) |
| CZ (1) | CZ281957B6 (online.php) |
| DD (1) | DD295378A5 (online.php) |
| DE (1) | DE4020475A1 (online.php) |
| FI (1) | FI92586C (online.php) |
| FR (1) | FR2648815B1 (online.php) |
| HU (1) | HU203549B (online.php) |
| IT (1) | IT1249001B (online.php) |
| NL (1) | NL9001459A (online.php) |
| RU (1) | RU1779253C (online.php) |
| YU (1) | YU124790A (online.php) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ530007A (en) | 2001-06-08 | 2006-02-24 | Sod Conseils Rech Applic | Somatostatin-dopamine chimeric analogues that retain both somatostatin and dopamine activity in vivo and display enhanced biological activity |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE107647T1 (de) * | 1984-04-09 | 1994-07-15 | Schering Ag | 2-substituierte ergolin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel. |
| CH658058A5 (en) * | 1984-06-21 | 1986-10-15 | Linnea Sa | Process for preparing lumilysergol derivatives |
-
1989
- 1989-06-27 HU HU893225A patent/HU203549B/hu not_active IP Right Cessation
-
1990
- 1990-06-20 CA CA002019407A patent/CA2019407C/en not_active Expired - Fee Related
- 1990-06-21 FR FR909007757A patent/FR2648815B1/fr not_active Expired - Lifetime
- 1990-06-22 US US07/542,168 patent/US5097031A/en not_active Expired - Lifetime
- 1990-06-26 YU YU01247/90A patent/YU124790A/xx unknown
- 1990-06-26 DD DD90342087A patent/DD295378A5/de not_active IP Right Cessation
- 1990-06-26 IT IT02076990A patent/IT1249001B/it active IP Right Grant
- 1990-06-26 JP JP2165835A patent/JPH03128374A/ja active Pending
- 1990-06-26 CH CH2131/90A patent/CH680445A5/de not_active IP Right Cessation
- 1990-06-26 NL NL9001459A patent/NL9001459A/nl not_active Application Discontinuation
- 1990-06-26 FI FI903196A patent/FI92586C/fi not_active IP Right Cessation
- 1990-06-27 DE DE4020475A patent/DE4020475A1/de not_active Withdrawn
- 1990-06-27 RU SU904830539A patent/RU1779253C/ru active
- 1990-06-27 CZ CS903211A patent/CZ281957B6/cs not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CZ281957B6 (cs) | 1997-04-16 |
| FI92586B (fi) | 1994-08-31 |
| YU124790A (en) | 1991-10-31 |
| FI903196A0 (fi) | 1990-06-26 |
| DD295378A5 (de) | 1991-10-31 |
| NL9001459A (nl) | 1991-01-16 |
| FR2648815A1 (fr) | 1990-12-28 |
| DE4020475A1 (de) | 1991-02-07 |
| CH680445A5 (online.php) | 1992-08-31 |
| CA2019407A1 (en) | 1990-12-27 |
| US5097031A (en) | 1992-03-17 |
| CA2019407C (en) | 1997-09-30 |
| IT9020769A1 (it) | 1991-12-26 |
| IT9020769A0 (it) | 1990-06-26 |
| JPH03128374A (ja) | 1991-05-31 |
| HU203549B (en) | 1991-08-28 |
| IT1249001B (it) | 1995-02-11 |
| CZ321190A3 (en) | 1997-01-15 |
| FI92586C (fi) | 1994-12-12 |
| RU1779253C (ru) | 1992-11-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |