FR2642649A1 - - Google Patents

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Publication number
FR2642649A1
FR2642649A1 FR9001332A FR9001332A FR2642649A1 FR 2642649 A1 FR2642649 A1 FR 2642649A1 FR 9001332 A FR9001332 A FR 9001332A FR 9001332 A FR9001332 A FR 9001332A FR 2642649 A1 FR2642649 A1 FR 2642649A1
Authority
FR
France
Prior art keywords
composition according
lower alkyl
alkyl
thromboxane
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
FR9001332A
Other languages
English (en)
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of FR2642649A1 publication Critical patent/FR2642649A1/fr
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR9001332A 1989-02-06 1990-02-06 Pending FR2642649A1 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30673489A 1989-02-06 1989-02-06

Publications (1)

Publication Number Publication Date
FR2642649A1 true FR2642649A1 (da) 1990-08-10

Family

ID=23186608

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9001332A Pending FR2642649A1 (da) 1989-02-06 1990-02-06

Country Status (6)

Country Link
JP (1) JPH02270826A (da)
CA (1) CA2007896A1 (da)
DE (1) DE4003392A1 (da)
FR (1) FR2642649A1 (da)
GB (1) GB2227664A (da)
IT (1) IT1238082B (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5021448A (en) * 1990-02-22 1991-06-04 Ciba-Geigy Corporation Method of reducing serum uric acid and/or increasing renal uric acid clearance with thromboxane synthetase inhibitor inhibitor and/or thromboxane receptor antagonist

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4537981A (en) * 1981-11-09 1985-08-27 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane and 7-oxabicycloheptene compounds
US4663336A (en) * 1985-07-01 1987-05-05 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted diamide and its congener prostaglandin analogs useful in the treatment of thrombotic disease

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4416896A (en) * 1982-05-17 1983-11-22 E. R. Squibb & Sons, Inc. 7-Oxabicyclopheptane substituted amino prostaglandin analogs useful in the treatment of thrombolytic disease

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4537981A (en) * 1981-11-09 1985-08-27 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane and 7-oxabicycloheptene compounds
US4663336A (en) * 1985-07-01 1987-05-05 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted diamide and its congener prostaglandin analogs useful in the treatment of thrombotic disease

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
HYPERTENSION, vol. 12, no. 3, 1988, pages 287-294; R.J. ROMAN et al.: "Influence of eicosanoids on renal function of DOCA-salt hypertensive rats" *
PHARMACOLOGY, vol. 34, no. 6, 1987, pages 301-308, S. KARGER AG, Basel, CH; W.A. SCHUMACHER et al.: "Effect of the thromboxane A2-receptor antanogists, SQ 29,548 and SQ 28,668, on the pulmonary hypertensive response to endotoxemia in swine" *
THE AMERICAN JOURNAL OF MEDICAL SCIENCE, vol. 295, no. 4, 1988, pages 263-267; M. MISTRY et al.: "Prostanoids as mediators of prohypertensive and antihypertensive mechanisms" *
THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, vol. 235, no. 2, 1985, pages 274-281, The American Society for Pharmalocogy and Experimental Therapeutics, US; H. DARUS et al.: "Beneficial effects of a new potent and specific thromboxane receptor antanogist (SQ-29,548) in Vitro and in Vivo" *

Also Published As

Publication number Publication date
IT9019256A0 (it) 1990-02-05
GB2227664A (en) 1990-08-08
CA2007896A1 (en) 1990-08-06
DE4003392A1 (de) 1990-08-09
GB9002194D0 (en) 1990-03-28
JPH02270826A (ja) 1990-11-05
IT1238082B (it) 1993-07-05
IT9019256A1 (it) 1990-08-07

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Legal Events

Date Code Title Description
ER Errata listed in the french official journal (bopi)

Free format text: 32/90