FR25F - N-substituted amino norcamphane derivatives with analeptic action. - Google Patents

N-substituted amino norcamphane derivatives with analeptic action.

Info

Publication number
FR25F
FR25F FR873190A FR873190A FR25F FR 25 F FR25 F FR 25F FR 873190 A FR873190 A FR 873190A FR 873190 A FR873190 A FR 873190A FR 25 F FR25 F FR 25F
Authority
FR
France
Prior art keywords
derivatives
substituted amino
norcamphane
analeptic
action
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR873190A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck KGaA
Original Assignee
E Merck AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DEM42332A external-priority patent/DE1110159B/en
Application filed by E Merck AG filed Critical E Merck AG
Application granted granted Critical
Publication of FR25F publication Critical patent/FR25F/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/38Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/44Oxygen atoms attached in position 4
    • C07D211/46Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74Oxygen atoms
    • C07D211/76Oxygen atoms attached in position 2 or 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
FR873190A 1959-08-01 1961-09-14 N-substituted amino norcamphane derivatives with analeptic action. Expired FR25F (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEM42332A DE1110159B (en) 1959-08-01 1959-08-01 Process for the preparation of analeptically active N-substituted amino orcamphan derivatives or of their acid addition salts and quaternary ammonium compounds
DEM46811A DE1201338B (en) 1959-08-01 1960-10-13 Process for the preparation of analeptically active N-substituted aminobicyclo-heptane derivatives or of their acid addition salts and quaternary ammonium compounds

Publications (1)

Publication Number Publication Date
FR25F true FR25F (en) 1963-03-29

Family

ID=7305711

Family Applications (1)

Application Number Title Priority Date Filing Date
FR873190A Expired FR25F (en) 1959-08-01 1961-09-14 N-substituted amino norcamphane derivatives with analeptic action.

Country Status (7)

Country Link
US (1) US3164601A (en)
BE (1) BE609074R (en)
CH (1) CH419105A (en)
DE (1) DE1201338B (en)
FR (1) FR25F (en)
GB (1) GB968714A (en)
SE (1) SE310175B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3228976A (en) * 1963-06-04 1966-01-11 American Home Prod 1, 4-bis-(aminomethyl)-1-cyclohexene compounds
US3483254A (en) * 1967-01-03 1969-12-09 Merck & Co Inc 2-bornanemethylamines
US3546233A (en) * 1967-05-15 1970-12-08 Upjohn Co Bis- and mono-quaternary salts of 1-(cyclicamino)cyclopropacycloalkanes
US3514486A (en) * 1968-05-23 1970-05-26 Miles Lab 3-isopropylnorbornanamine
DE4019782A1 (en) * 1990-06-21 1992-01-02 Basf Ag 9-AMINO-2-PHENYLBICYCLO (3.3.1.) AND 9-AMINO-2-PHENYLBICYCLO (3.3.1.) NON-2-ENE AND THERAPEUTIC AGENTS CONTAINING THEM
US6979698B1 (en) 1997-08-11 2005-12-27 Targacept, Inc. Method of treating cognitive deficits in learning and memory
US6034079A (en) * 1997-08-11 2000-03-07 University Of South Florida Nicotine antagonists for nicotine-responsive neuropsychiatric disorders

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2573644A (en) * 1949-03-22 1951-10-30 Smith Kline French Lab beta-chloroethyl aminoindanes
US2904591A (en) * 1955-02-25 1959-09-15 Ferrosan Ab Alpha-alkyl-propiophenones
DE1039061B (en) * 1955-06-06 1958-09-18 Merck & Co Inc Process for the preparation of N-substituted 3-aminoisocamphane compounds, their salts, quaternary ammonium compounds and optically active isomers
US3014037A (en) * 1957-09-12 1961-12-19 Searle & Co N-alkoxyphenalkyl-alpha, alpha-diphenyl-4-piperidinemethanols and processes
US2912459A (en) * 1957-10-24 1959-11-10 Ethicon Inc 2-halo alkanoyl aminobicyclo (2, 2, 1) heptane
US2955073A (en) * 1958-06-02 1960-10-04 Burroughs Wellcome Co Method of treating febrile convulsions
DE1110159B (en) * 1959-08-01 1961-07-06 Merck Ag E Process for the preparation of analeptically active N-substituted amino orcamphan derivatives or of their acid addition salts and quaternary ammonium compounds
US3074961A (en) * 1960-08-11 1963-01-22 Mcneilab Inc Certain new norbornenes
US2986573A (en) * 1961-01-18 1961-05-30 Schering Corp Method for the treatment of hypertension

Also Published As

Publication number Publication date
US3164601A (en) 1965-01-05
DE1201338B (en) 1965-09-23
CH419105A (en) 1966-08-31
GB968714A (en) 1964-09-02
SE310175B (en) 1969-04-21
BE609074R (en) 1962-04-12

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