FR2599033A1 - Derives des 3-(hydroxymethyl)-isoquinoleine, procede pour les preparer et compositions pharmaceutiques les contenant - Google Patents

Derives des 3-(hydroxymethyl)-isoquinoleine, procede pour les preparer et compositions pharmaceutiques les contenant Download PDF

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Publication number
FR2599033A1
FR2599033A1 FR8707119A FR8707119A FR2599033A1 FR 2599033 A1 FR2599033 A1 FR 2599033A1 FR 8707119 A FR8707119 A FR 8707119A FR 8707119 A FR8707119 A FR 8707119A FR 2599033 A1 FR2599033 A1 FR 2599033A1
Authority
FR
France
Prior art keywords
general formula
isoquinoline
group
represent
hydroxymethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR8707119A
Other languages
English (en)
French (fr)
Inventor
Gyorgy Rabloczky
Jeno Korosi
Tibor Lang
Istvan Ling
Tamas Hamori
Maria Kuhar-Nee-Kurthy
Istvan Elekes
Peter Botka
Andras Varro
Sandor Elek
Judit Sarossy-Nee-Kincsesy
Gabor Zolyomi
Zsuzsanna Lang-Nee-Rihmer
Imre Moravcsik
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Egis Gyógyszergyár Zrt
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Egis Gyógyszergyár Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar, Egis Gyógyszergyár Zrt filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of FR2599033A1 publication Critical patent/FR2599033A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
FR8707119A 1986-05-21 1987-05-21 Derives des 3-(hydroxymethyl)-isoquinoleine, procede pour les preparer et compositions pharmaceutiques les contenant Withdrawn FR2599033A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU862141A HU196758B (en) 1986-05-21 1986-05-21 Process for production of 3-hidroxi-methil-quinolines and medical compositions containing them

Publications (1)

Publication Number Publication Date
FR2599033A1 true FR2599033A1 (fr) 1987-11-27

Family

ID=10957979

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8707119A Withdrawn FR2599033A1 (fr) 1986-05-21 1987-05-21 Derives des 3-(hydroxymethyl)-isoquinoleine, procede pour les preparer et compositions pharmaceutiques les contenant

Country Status (22)

Country Link
US (1) US4785104A (enExample)
JP (1) JPS6339863A (enExample)
BE (1) BE1000719A4 (enExample)
BG (1) BG47197A3 (enExample)
CH (1) CH673280A5 (enExample)
CS (1) CS264293B2 (enExample)
DD (1) DD268940A5 (enExample)
DE (1) DE3717079A1 (enExample)
DK (1) DK258287A (enExample)
ES (1) ES2005583A6 (enExample)
FI (1) FI872256A7 (enExample)
FR (1) FR2599033A1 (enExample)
GB (1) GB2190678B (enExample)
HU (1) HU196758B (enExample)
IL (1) IL82614A0 (enExample)
IT (1) IT1208046B (enExample)
NL (1) NL8701214A (enExample)
PL (1) PL265811A1 (enExample)
PT (1) PT84924B (enExample)
SE (1) SE8702119L (enExample)
SU (1) SU1551245A3 (enExample)
YU (1) YU90787A (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2625743A1 (fr) * 1988-01-08 1989-07-13 Sandoz Sa Derives d'isoquinoleine, leur preparation et leur utilisation

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9027055D0 (en) * 1990-12-13 1991-02-06 Sandoz Ltd Organic compounds
GB9322828D0 (en) * 1993-11-05 1993-12-22 Sandoz Ltd Organic compounds
WO2002010135A1 (en) * 2000-08-01 2002-02-07 Ono Pharmaceutical Co., Ltd. 3,4-dihydroisoquinoline derivative compounds and drugs containing these compounds as the active ingredient
WO2002030888A2 (en) 2000-10-10 2002-04-18 Calyx Therapeutics, Inc. Tricyclic compounds and uses thereof
AR035513A1 (es) * 2000-12-23 2004-06-02 Hoffmann La Roche Derivados de tetrahidropiridina, proceso para prepararlos, composiciones farmaceuticas que los contienen, y uso de dichos compuestos en la preparacion de medicamentos
RU2417221C1 (ru) * 2009-11-02 2011-04-27 Государственное образовательное учреждение высшего профессионального образования "Пермский государственный университет" (1z,3z)-4-арил-4-гидрокси-1-(3,3-диалкил-3,4-дигидроизохинолин-1(2н)-илиден)-бут-3-ен-4-оны и способ их получения

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2154500A1 (enExample) * 1971-09-22 1973-05-11 Rolland Sa A
EP0094271A2 (fr) * 1982-04-27 1983-11-16 Pharmuka Laboratoires Nouveaux dérivés d'arène et d'hétéroarènecarboxamides, leur procédé de préparation et médicaments les contenant

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2154500A1 (enExample) * 1971-09-22 1973-05-11 Rolland Sa A
EP0094271A2 (fr) * 1982-04-27 1983-11-16 Pharmuka Laboratoires Nouveaux dérivés d'arène et d'hétéroarènecarboxamides, leur procédé de préparation et médicaments les contenant

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2625743A1 (fr) * 1988-01-08 1989-07-13 Sandoz Sa Derives d'isoquinoleine, leur preparation et leur utilisation
BE1002730A3 (fr) * 1988-01-08 1991-05-21 Sandoz Sa Derives d'isoquinoleine, leur preparation et leur utilisation.
GR890100008A (el) * 1988-01-08 1994-03-31 Sandoz Ag Παράγωγα ισοκινολίνης, παρασκευή τους και χρήση τους.

Also Published As

Publication number Publication date
BG47197A3 (bg) 1990-05-15
CS264293B2 (en) 1989-06-13
GB2190678A (en) 1987-11-25
DD268940A5 (de) 1989-06-14
GB8712047D0 (en) 1987-06-24
HUT44017A (en) 1988-01-28
CH673280A5 (enExample) 1990-02-28
GB2190678B (en) 1990-06-20
BE1000719A4 (fr) 1989-03-21
DK258287A (da) 1987-11-22
PL265811A1 (en) 1988-07-21
YU90787A (en) 1988-08-31
SE8702119D0 (sv) 1987-05-21
PT84924B (en) 1989-07-20
SU1551245A3 (ru) 1990-03-15
JPS6339863A (ja) 1988-02-20
NL8701214A (nl) 1987-12-16
FI872256A7 (fi) 1987-11-22
SE8702119L (sv) 1987-11-22
CS369187A2 (en) 1988-09-16
DK258287D0 (da) 1987-05-21
IT8720618A0 (it) 1987-05-21
US4785104A (en) 1988-11-15
HU196758B (en) 1989-01-30
IL82614A0 (en) 1987-11-30
FI872256A0 (fi) 1987-05-21
ES2005583A6 (es) 1989-03-16
IT1208046B (it) 1989-06-01
DE3717079A1 (de) 1988-01-07
PT84924A (en) 1987-06-01

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