FR2595352B1 - Derives de l'indole utiles comme medicaments et procede et intermediaires pour leur preparation - Google Patents

Derives de l'indole utiles comme medicaments et procede et intermediaires pour leur preparation

Info

Publication number
FR2595352B1
FR2595352B1 FR878700108A FR8700108A FR2595352B1 FR 2595352 B1 FR2595352 B1 FR 2595352B1 FR 878700108 A FR878700108 A FR 878700108A FR 8700108 A FR8700108 A FR 8700108A FR 2595352 B1 FR2595352 B1 FR 2595352B1
Authority
FR
France
Prior art keywords
medicaments
intermediates
preparation
indole derivatives
derivatives useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR878700108A
Other languages
English (en)
Other versions
FR2595352A1 (fr
Inventor
Keith Mills
Ian Harold Coates
David Edmund Bays
Colin Frederick Webb
Michael Dennis Dowle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of FR2595352A1 publication Critical patent/FR2595352A1/fr
Application granted granted Critical
Publication of FR2595352B1 publication Critical patent/FR2595352B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
FR878700108A 1986-01-08 1987-01-08 Derives de l'indole utiles comme medicaments et procede et intermediaires pour leur preparation Expired - Fee Related FR2595352B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868600398A GB8600398D0 (en) 1986-01-08 1986-01-08 Chemical compounds

Publications (2)

Publication Number Publication Date
FR2595352A1 FR2595352A1 (fr) 1987-09-11
FR2595352B1 true FR2595352B1 (fr) 1990-07-13

Family

ID=10591075

Family Applications (1)

Application Number Title Priority Date Filing Date
FR878700108A Expired - Fee Related FR2595352B1 (fr) 1986-01-08 1987-01-08 Derives de l'indole utiles comme medicaments et procede et intermediaires pour leur preparation

Country Status (11)

Country Link
JP (1) JPS62228057A (fr)
AT (1) AT386197B (fr)
AU (1) AU597324B2 (fr)
BE (1) BE1000072A4 (fr)
CH (1) CH671017A5 (fr)
DE (1) DE3700407A1 (fr)
FR (1) FR2595352B1 (fr)
GB (2) GB8600398D0 (fr)
IT (1) IT1216772B (fr)
NL (1) NL8700027A (fr)
ZA (1) ZA87104B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8600397D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
US5225431A (en) * 1987-10-23 1993-07-06 Burroughs Wellcome Co. Therapeutic substituted indole compounds and compositions thereof
GB8819024D0 (en) * 1988-08-10 1988-09-14 Glaxo Group Ltd Chemical compounds
IL98392A (en) * 1990-06-07 1996-01-19 Wellcome Found History of indole, their preparation and the pharmaceutical preparations containing them
GB9012672D0 (en) * 1990-06-07 1990-08-01 Wellcome Found Therapeutic heterocyclic compounds
TW263508B (fr) * 1991-02-12 1995-11-21 Pfizer
US5206377A (en) * 1991-12-05 1993-04-27 Whitby Research, Inc. Compounds useful as antiproliferative agents
GB9201038D0 (en) * 1992-01-16 1992-03-11 Glaxo Group Ltd Chemical compounds
US5409941A (en) * 1992-02-03 1995-04-25 Pfizer Inc. 5-heteroyl indole derivatives
GB9211277D0 (en) 1992-05-28 1992-07-15 Glaxo Group Inc Pharmaceutical compositions
US5496957A (en) * 1993-09-01 1996-03-05 Virginia Commonwealth University Tryptamine analogs with 5-HT1D selectivity
CA2147991A1 (fr) * 1993-09-01 1995-03-09 Richard A. Glennon Analogues de tryptamine avec selectivite pour le recepteur 5-ht1d
JP4897221B2 (ja) 2002-12-20 2012-03-14 チバ ホールディング インコーポレーテッド アミン類の合成及びその合成のための中間体

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB147107A (en) * 1915-04-06 1921-10-07 Zeiss Carl Improvements in finders for photographic apparatus
GB145459A (en) * 1917-03-24 1921-04-21 Anschuetz & Co Gmbh Improvements in indicators for the turning of aircraft about a vertical axis
ZA795239B (en) * 1978-10-12 1980-11-26 Glaxo Group Ltd Heterocyclic compounds
NZ197998A (en) * 1980-08-12 1985-08-16 Glaxo Group Ltd 5-amino(methyl)-1h-indol-3-ylalkaneamines
ZW19381A1 (en) * 1980-08-12 1983-03-09 Glaxo Group Ltd Heterocyclic compounds
GB8600397D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
FR2903394B1 (fr) * 2006-07-05 2008-09-19 Pierre Marcelli Devidoir a mandrin expansible pour bobine
BRPI0808952A2 (pt) * 2007-04-06 2014-08-26 Gaiasoft Ip Ltd "sistema de entrega de conteúdo, mecanismo intermediário de conteúdo, detentor confiável do mecanismo de dados do perfil e método para entregar conteúdo"

Also Published As

Publication number Publication date
AU6741887A (en) 1987-07-09
FR2595352A1 (fr) 1987-09-11
NL8700027A (nl) 1987-08-03
GB2186874A (en) 1987-08-26
IT8747506A0 (it) 1987-01-08
IT1216772B (it) 1990-03-14
GB8700381D0 (en) 1987-02-11
ZA87104B (en) 1987-12-30
CH671017A5 (fr) 1989-07-31
BE1000072A4 (fr) 1988-02-02
DE3700407A1 (de) 1987-07-09
GB8600398D0 (en) 1986-02-12
ATA2487A (de) 1987-12-15
GB2186874B (en) 1990-02-07
AU597324B2 (en) 1990-05-31
AT386197B (de) 1988-07-11
JPS62228057A (ja) 1987-10-06

Similar Documents

Publication Publication Date Title
FR2555987B1 (fr) Nouveaux derives d'indole utiles comme medicaments et intermediaires et procedes pour leur preparation
BE895080A (fr) Procede de preparation de derives de 3-hydroxy-ml-236b connus comme m-4 et m-4'
FR2603899B1 (fr) Procede perfectionne pour l'expression de recombinants
FR2611366B1 (fr) Nouvelles cetones tricycliques utiles comme medicaments, procede et intermediaires pour leur preparation
FR2595351B1 (fr) Derives d'indole, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2572094B1 (fr) Procede pour la preparation continue de l'ethanol
MA21645A1 (fr) Procede pour la preparation de nouveaux derives d'rtemisinine.
FR2509300B1 (fr) Derives d'azetidinone et procede pour leur preparation
FR2595352B1 (fr) Derives de l'indole utiles comme medicaments et procede et intermediaires pour leur preparation
MA20387A1 (fr) Pyridazinamines utiles comme agents anti-viraux et procede pour leur preparation
MA21413A1 (fr) Nouveau procede de preparation d'alcoxy-guanine
RO96413A (fr) Procede pour la preparation des derives de thoadiazole
RO93218A (fr) Procede pour la preparation des derives de 2-oxyndole
FR2627493B1 (fr) Procede de preparation de derives d'isoquinoleine
FR2512820B1 (fr) Nouveaux derives de benzothiazoline utiles comme medicaments et procede pour leur preparation
RO94658A (fr) Procede de preparation d'un derive de n-(3-chlore-4-isopropyle-phenyle)-carboxamide
FR2526022B1 (fr) Derives de l'ergoline, procede pour les preparer et leur emploi comme medicaments
FR2600061B1 (fr) Derives d'indole, composition pharmaceutique les contenant et procede pour leur preparation
FR2552433B1 (fr) Nouveaux derives de 1,3,4-thiadiazole, procede pour leur preparation et leur utilisation comme agents anti-ulcere
FR2559771B1 (fr) Derives de la 3-pyrrolidinopropiophenone et procede pour leur preparation
FR2557109B1 (fr) Nouveaux derives de 2-arylbenzothiazoline utiles comme medicaments et procede pour leur preparation
FR2603036B1 (fr) Derives de 2,3-dihydrofuranne, leur procede de preparation, leur utilisation comme intermediaire pour la preparation de tetrahydrofuranne
MA21273A1 (fr) Procede pour l'obtention de derives d'hydrazine utiles comme antihypertenseurs;
FR2547822B1 (fr) Acylpiperazinoquinazolines substituees utiles comme medicaments et procede pour leur preparation
FR2644161B1 (fr) Procede de preparation d'amides n-arylsubstitues

Legal Events

Date Code Title Description
ST Notification of lapse