FR2594333A1 - New composition for cosmetic use, characterised by the constituents of snails' eggs - Google Patents

New composition for cosmetic use, characterised by the constituents of snails' eggs Download PDF

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Publication number
FR2594333A1
FR2594333A1 FR8602139A FR8602139A FR2594333A1 FR 2594333 A1 FR2594333 A1 FR 2594333A1 FR 8602139 A FR8602139 A FR 8602139A FR 8602139 A FR8602139 A FR 8602139A FR 2594333 A1 FR2594333 A1 FR 2594333A1
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France
Prior art keywords
constituents
eggs
snails
cosmetic use
new composition
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Granted
Application number
FR8602139A
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French (fr)
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FR2594333B1 (en
Inventor
Simonne Legrand
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ETU PHYSIO HYGIENE COSMET CENT
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ETU PHYSIO HYGIENE COSMET CENT
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Priority to FR8602139A priority Critical patent/FR2594333B1/en
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)

Abstract

The invention relates to a new biological composition intended for cosmetic use, characterised by the mucoproteins, proteins and nucleic acids obtained by extraction from snails' eggs.

Description

II est connu que les acides désoxyribonucléiques et ribonucléiques jouent un rôle particulièrement important dans l'équilibre physiologique des différentes couches cellulaires cutanées (OTANI et col. - Epidermal DNA synthesis. It is known that deoxyribonucleic and ribonucleic acids play a particularly important role in the physiological balance of the various skin cell layers (OTANI et al. - Epidermal DNA synthesis.

The Journal of Investigative dermatology 1980 75-3750 et en particulier dans les processus de kératinisation (Biochemistry and physiology of the skin par GOLDSMITH - Oxford University
Press 1983).The Journal of Investigative dermatology 1980 75-3750 and in particular in the keratinization processes (Biochemistry and physiology of the skin by GOLDSMITH - Oxford University
Press 1983).

Quant aux glycoprotéines, comportant une variété de structures, parmi lesquelles figurent les mucoprotéines responsables de la viscosité de certains fluides biologiques, celles-ci jouent un rôle également important dans la stabilité du derme sous forme de substance fondamentale, Par hydrolyse de ces glucoprotéines, on obtient un ou plusieurs sucres, des acides aminés spécifiques au type de protéines combiné avec les dits sucres ainsi que l'ion sulfate. As for glycoproteins, comprising a variety of structures, among which are the mucoproteins responsible for the viscosity of certain biological fluids, these play an equally important role in the stability of the dermis in the form of a fundamental substance, By hydrolysis of these glucoproteins, obtains one or more sugars, amino acids specific to the type of protein combined with the said sugars as well as the sulfate ion.

De multiples publications ont montré les interfé- rences existant entre les structures énumérées avec la biosynthèse des protéines cutanées. Numerous publications have shown the interferences existing between the structures listed with the biosynthesis of skin proteins.

La présente invention a pour objet la réalisation de compositions comportant des acides nucléiques et mucoprotéines, caractérisées en ce qu'elles proviennent de l'extraction d'oeufs dtescargots, ceci simplement pqr l'eau ou par tous solvants hydrophiles , n'altérant pas les constituants. The subject of the present invention is the production of compositions comprising nucleic acids and mucoproteins, characterized in that they come from the extraction of snail eggs, this simply by water or by any hydrophilic solvent, not altering the constituents.

Dans le cadre de la présente invention, les oeufs d'escargots sont deshydratés par chauffage à 80 . On obtient ainsi des petites boules blanchâtres, drune certaine dureté du fait de la présence de carbonate de calcium. Ces particule sont finement broyées, puis traitées par l'eau à ébullition durant une heure environ. Par filtration ou centrifugation, on sépare le carbonate de chaux de la solution. On obtient une solution limpide de viscosité variable selon la concentration en substances organiques.Une solution comportant environ 10 % de matière sèche indique
Cendres ................ 0,001 %
Azote sur l'anhydre .......... 0,2 %
Magnésium a 0,07 %
Sulfates ............... 0,02 %
Détermination des constituants
L'examen d'une telle solution montre l'absence de Polypeptides libres. Il en est de même pour les acides aminés et les sucres, ce qui montre ainsi que les constituants n'ont pas été dégradés.In the context of the present invention, the snail eggs are dehydrated by heating to 80. This gives small whitish balls, a certain hardness due to the presence of calcium carbonate. These particles are finely ground, then treated with boiling water for about an hour. By filtration or centrifugation, the carbonate of lime is separated from the solution. A clear solution of variable viscosity is obtained depending on the concentration of organic substances. A solution comprising approximately 10% dry matter indicates
Ashes ................ 0.001%
Nitrogen on anhydrous .......... 0.2%
0.07% magnesium
Sulfates ............... 0.02%
Determination of constituents
Examination of such a solution shows the absence of free polypeptides. It is the same for amino acids and sugars, which shows that the constituents have not been degraded.

Par hydrolyse de la solution avec 50 % d'acide chlorhydrique durant une heure, on libère ainsi les constituants fondamentaux des acides nucléiques et des glycoprotéines. Par /'étude de ces constituants à l'aide de chromatographie sur couche mince, on met en évidence les substances suivantes :
On constate dans lthydrolysat la présence de 14 acides aminés libérés des chaines protéiniques. Les acides aminés dominants sont le tryptophane, lthydroxyproline et l'acide aspartique.On trouve, en moins grande quantité, de lthydroxylysine. Soulignons que lthydroxyproline et lthydroxylysine sont les acides aminés caractérisant le collagène du derme, montrant ainsi un rapport d'affinité biologique entre l'extrait et la peau.By hydrolysis of the solution with 50% hydrochloric acid for one hour, the fundamental constituents of the nucleic acids and of the glycoproteins are released. By studying these constituents using thin layer chromatography, the following substances are highlighted:
We observe in the hydrolyzate the presence of 14 amino acids released from the protein chains. The dominant amino acids are tryptophan, hydroxyproline and aspartic acid, but less of them are hydroxylysine. Note that hydroxyproline and hydroxylysine are the amino acids characterizing collagen in the dermis, thus showing a relationship of biological affinity between the extract and the skin.

L'examen chromatographique des sucres. montre la présence detrois sucres : désoxyribose, ribose et glucose ; les deux premiers caractérisant la présence d'acides nucléiques, le dernier celui de mucoprotéines.  Chromatographic examination of sugars. shows the presence of three sugars: deoxyribose, ribose and glucose; the first two characterizing the presence of nucleic acids, the last that of mucoproteins.

La présence des acides nucléiques est confirmée par la recherche des bases puriques et pyrimidiques, selon la technique décrite dans "pharmacopée Française". On met ainsi en évidence l'adénine, la cytosine, la thymine et la guanine. The presence of nucleic acids is confirmed by the search for purine and pyrimidine bases, according to the technique described in "French pharmacopoeia". Adenine, cytosine, thymine and guanine are thus highlighted.

Les recherches effectuées dans le but de mettre en évidence les lipides dans l'extrait, montre que celui-ci en est pratiquement dépourvu. On ne trouve que de faibles quantités d'esters de cholestérol. Research carried out with the aim of highlighting the lipids in the extract, shows that the latter is practically devoid of it. Only small amounts of cholesterol esters are found.

La précipitation de la solution par l'alcool ou l'acide acétique confirme la présence d'acide mucoitique sulfurique. The precipitation of the solution by alcohol or acetic acid confirms the presence of mucoitic sulfuric acid.

Dans le cadre de la présente invention, on réalisera avantageusement des compositions cosmétiques destinées au traitement de la peau et de ses annexes caractérisées en ce quelles comportent des substances biologiques naturelles, non modifiées par des interventions pouvant altérer leurs constituants et douées d'une potentialité biologique importante pour le revêtement cutané. In the context of the present invention, cosmetic compositions intended for the treatment of the skin and its appendices, characterized in that they contain natural biological substances, unmodified by interventions which can alter their constituents and which have biological potential, will advantageously be produced. important for the skin coating.

A titre d'exemples non 1imitatifs, on pourra réaliser des compositions cosmétiques comme suit :
Lotion capillaire :
Extrait d'oeufs d'escargots .......... 5 %
Alcool .............................. 10 %
Eau ................................. qs
Parfum .............................. qs
Lotion tonique :
Extrait d'oeufs d'escargots .......... 5 %
Alcool .............................. 10 %
Glycérol ............................ 5 % Parfum 0 , . ... qs
Eau ................................ qs
Crème tonique
Extrait d'oeufs d'escargots ............ 5 %
Stéarine .......................... 10 %
Alcool'gras polyoxyéthyléné 6 %
Glycérol .................. 10 %
Eau .................... qs 100
Parfum ................................. qs
Crème de protection solaire :
Ecran antisolire ....................... 5 %
Extrait d'oeufs d'escargots 5 %
Lysofat O .............................. 5 %
Stéarate de polyoxyéthylène glycol .......... 10 %
Alcool gras polyoxyéthyléné ......... 5 %
Glycérol ............................... 10 %
Eau .................................... qs 100 Parfum , . qs
Conservateur .......................... qs
Crème hydratante : :
Extrait d'oeufs d'escargots 5 %
Lysofat O ............................. 5 %
Esters d'acides gras ............. 10 %
Alcool cétylique polyoxyéthyléné ....... 6 %
Eau .................................... qs 100
Parfum ................................. qs
Conservateur ........................... qs As nonlimiting examples, cosmetic compositions can be produced as follows:
Hair lotion:
Snail egg extract .......... 5%
Alcohol .............................. 10%
Water ................................. qs
Perfume .............................. qs
Tonic lotion :
Snail egg extract .......... 5%
Alcohol .............................. 10%
Glycerol ............................ 5% Perfume 0,. ... qs
Water ................................ qs
Tonic cream
Snail egg extract ............ 5%
Stearin .......................... 10%
Polyoxyethylenated alcohol 6%
Glycerol .................. 10%
Water .................... qs 100
Perfume ................................. qs
Sun protection cream:
Anti-sunscreen ....................... 5%
Snail egg extract 5%
Lysofat O .............................. 5%
Polyoxyethylene glycol stearate .......... 10%
Polyoxyethylenated fatty alcohol ......... 5%
Glycerol ............................... 10%
Water .................................... qs 100 Perfume,. qs
Preservative .......................... qs
Moisturizer : :
Snail egg extract 5%
Lysofat O ............................. 5%
Esters of fatty acids ............. 10%
Polyoxyethylenated cetyl alcohol ....... 6%
Water .................................... qs 100
Perfume ................................. qs
Curator ........................... qs

Claims (3)

des structures biologiques. biological structures. polaire tel que l'eau par exemple, conservant l'intégrité polar such as water for example, retaining integrity d'escargots deshydratés ou non, traites par un solvant dehydrated snails or not, treated with a solvent REVENDICATIONS 1 - Nouvelle composition biologique obtenue à partir d'oeufs CLAIMS 1 - New biological composition obtained from eggs 2 - Nouvelle composition biologique obtenue selon la reven2 - New biological composition obtained according to the revenue dication 1, caractérisée par la présence d'acides indication 1, characterized by the presence of acids désoxyribonucléique, ribonucléique et par des acides deoxyribonucleic, ribonucleic and by acids muco it iques sulfuriques. sulfuric mucositis. 3 - Nouvelle composition biologique selon les revendications3 - New biological composition according to the claims 1 et 2, caractérisées par leur application dans le 1 and 2, characterized by their application in the domaine cosmétique.  cosmetic field.
FR8602139A 1986-02-18 1986-02-18 NEW COMPOSITION FOR COSMETIC USE CHARACTERIZED BY THE CONSTITUENTS OF SNAIL EGGS Expired FR2594333B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR8602139A FR2594333B1 (en) 1986-02-18 1986-02-18 NEW COMPOSITION FOR COSMETIC USE CHARACTERIZED BY THE CONSTITUENTS OF SNAIL EGGS

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Application Number Priority Date Filing Date Title
FR8602139A FR2594333B1 (en) 1986-02-18 1986-02-18 NEW COMPOSITION FOR COSMETIC USE CHARACTERIZED BY THE CONSTITUENTS OF SNAIL EGGS

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FR2594333A1 true FR2594333A1 (en) 1987-08-21
FR2594333B1 FR2594333B1 (en) 1989-05-12

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011092350A1 (en) * 2010-01-28 2011-08-04 Industrial Farmacéutica Cantabria, S.A. Product for the preparation of dermatological, cosmetic or cosmeceutical compositions intended for skin treatment
GR1010331B (en) * 2019-10-23 2022-10-24 Αθανασιος Αστεριου Γκογκας Cosmetics, medicinal products and nutritional supplements made of white caviar-snail eggs

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2036453A5 (en) * 1969-03-14 1970-12-24 Henry Michel Cosmetic preparations additive
DE2032988A1 (en) * 1970-07-03 1972-01-05 Theurer, Karl, Dr. med., 7000 Stuttgart Ovular and seminal cell extracts - having a haploid chromosome set for therapeutic and diagnostic use
FR2094109A7 (en) * 1970-06-08 1972-02-04 Lubowe Irwin
FR2205304A1 (en) * 1972-11-06 1974-05-31 Pierret Colette Beauty treatment - for the skin with compsn contg cellular material esp rna and dna
JPS5553219A (en) * 1978-10-14 1980-04-18 Grelan Pharmaceut Co Ltd Anticancer active substance and its preparation
FR2487197A2 (en) * 1979-05-11 1982-01-29 Thomas Andre Extraction of glyco:proteins and muco:polysaccharide(s) - by macerating animal tissue in a slightly alkaline buffer
FR2502007A1 (en) * 1981-03-18 1982-09-24 Simonin Renee Products contg. mollusc eggs prior to deposition - having cicatrising, revitalising and rejuvenating effects

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2036453A5 (en) * 1969-03-14 1970-12-24 Henry Michel Cosmetic preparations additive
FR2094109A7 (en) * 1970-06-08 1972-02-04 Lubowe Irwin
DE2032988A1 (en) * 1970-07-03 1972-01-05 Theurer, Karl, Dr. med., 7000 Stuttgart Ovular and seminal cell extracts - having a haploid chromosome set for therapeutic and diagnostic use
FR2205304A1 (en) * 1972-11-06 1974-05-31 Pierret Colette Beauty treatment - for the skin with compsn contg cellular material esp rna and dna
JPS5553219A (en) * 1978-10-14 1980-04-18 Grelan Pharmaceut Co Ltd Anticancer active substance and its preparation
FR2487197A2 (en) * 1979-05-11 1982-01-29 Thomas Andre Extraction of glyco:proteins and muco:polysaccharide(s) - by macerating animal tissue in a slightly alkaline buffer
FR2502007A1 (en) * 1981-03-18 1982-09-24 Simonin Renee Products contg. mollusc eggs prior to deposition - having cicatrising, revitalising and rejuvenating effects

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BIOLOGICAL ABSTRACTS, vol. 68, (3259); R.NAGABHUSHANAM et al.: "Composition of egg capsules of the pulmonate fresh water snails indoplanorbis-exustus and gyraulus-convexiusculus" & DEP. ZOOL., MARATHWADA UNIV., AURANGABAD 431002, MAHARASHTRA, INDIA MARATHWADA university Journal of Science(INDIA) 1977 (RECD. 1978). Vol. 16, no. 9, pages 205-208, English Coden: MUNSD *
BIOLOGICAL ABSTRACTS, vol. 81, (63273); C.A.M. VAN DONGEN et al.: "Composition of the nucleotides pool in a morphogenetic compartment in eggs of nassarius-reticulatus mollusca analyzed by capillary isotachophoresis" & DEP. EXP. EMBRYOL., ZOOL. LAB., STATE UNIV. UTRECHT, P.O. BOX 80058, 3508 TB UTRECHT, NETH - EXPERIMENTAL CELL RESEARCH(US) 1985, Vol. 161, no. 2, pages 406-420, English Coden: ECREA *
PATENTS ABSTRACTS OF JAPAN, vol. 4, no. 89 (C-16)[571], 25 juin 1980, page 80 C 16; & JP - A - 55 53 219 (GRELAN SEIYAKU K.K.) 18-04-1980 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011092350A1 (en) * 2010-01-28 2011-08-04 Industrial Farmacéutica Cantabria, S.A. Product for the preparation of dermatological, cosmetic or cosmeceutical compositions intended for skin treatment
US20120107410A1 (en) * 2010-01-28 2012-05-03 Industrial Farmaceutica Cantabria, S.A. Product for the preparation of dermatological, cosmetic or cosmeceutical compositions intended for skin treatment
ES2398809A1 (en) * 2010-01-28 2013-03-21 Industrial Farmacéutica Cantabria, S.A. Product for the preparation of dermatological, cosmetic or cosmeceutical compositions intended for skin treatment
US10391050B2 (en) 2010-01-28 2019-08-27 Industrial Farmacéutica Cantabria, S.A. Dermatological, cosmetic or cosmeceutical compositions intended for skin treatment
GR1010331B (en) * 2019-10-23 2022-10-24 Αθανασιος Αστεριου Γκογκας Cosmetics, medicinal products and nutritional supplements made of white caviar-snail eggs

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FR2594333B1 (en) 1989-05-12

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