FR2586705B1 - Procede pour localiser et purifier de l'adn contenant des faux appariements individuels de bases - Google Patents

Procede pour localiser et purifier de l'adn contenant des faux appariements individuels de bases

Info

Publication number
FR2586705B1
FR2586705B1 FR8612189A FR8612189A FR2586705B1 FR 2586705 B1 FR2586705 B1 FR 2586705B1 FR 8612189 A FR8612189 A FR 8612189A FR 8612189 A FR8612189 A FR 8612189A FR 2586705 B1 FR2586705 B1 FR 2586705B1
Authority
FR
France
Prior art keywords
localizing
dna containing
purifying dna
individual matches
containing false
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8612189A
Other languages
English (en)
Other versions
FR2586705A1 (fr
Inventor
John P Ford
David F Novack
Nancy J Casna
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lifecodes Corp
Original Assignee
Lifecodes Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lifecodes Corp filed Critical Lifecodes Corp
Publication of FR2586705A1 publication Critical patent/FR2586705A1/fr
Application granted granted Critical
Publication of FR2586705B1 publication Critical patent/FR2586705B1/fr
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/803—Physical recovery methods, e.g. chromatography, grinding

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Electrochemistry (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
FR8612189A 1985-08-29 1986-08-28 Procede pour localiser et purifier de l'adn contenant des faux appariements individuels de bases Expired FR2586705B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/770,841 US4794075A (en) 1985-08-29 1985-08-29 Method for locating and purifying DNA containing single base mismatches

Publications (2)

Publication Number Publication Date
FR2586705A1 FR2586705A1 (fr) 1987-03-06
FR2586705B1 true FR2586705B1 (fr) 1989-01-06

Family

ID=25089859

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8612189A Expired FR2586705B1 (fr) 1985-08-29 1986-08-28 Procede pour localiser et purifier de l'adn contenant des faux appariements individuels de bases

Country Status (7)

Country Link
US (1) US4794075A (fr)
JP (1) JPS62158499A (fr)
BE (1) BE905348A (fr)
CA (1) CA1286618C (fr)
DE (1) DE3629190A1 (fr)
FR (1) FR2586705B1 (fr)
GB (1) GB2179735B (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5217863A (en) * 1988-02-04 1993-06-08 Medical Research Council Detection of mutations in nucleic acids
GB8802508D0 (en) * 1988-02-04 1988-03-02 Medical Res Council Detection of mutations in nucleic acids
US4879214A (en) * 1988-11-15 1989-11-07 E. I. Du Pont De Nemours And Company Differentiation of nucleic acid segments on the basis of nucleotide differences
CA2012379C (fr) * 1989-04-24 2000-01-25 Gary W. Slater Methode de preparation et de separation de macromolecules
AU5645690A (en) * 1989-05-05 1990-11-29 Lifecodes Corporation Method for genetic analysis of a nucleic acid sample
US6008031A (en) * 1989-05-12 1999-12-28 Duke University Method of analysis and manipulation of DNA utilizing mismatch repair systems
US5556750A (en) * 1989-05-12 1996-09-17 Duke University Methods and kits for fractionating a population of DNA molecules based on the presence or absence of a base-pair mismatch utilizing mismatch repair systems
US5459039A (en) * 1989-05-12 1995-10-17 Duke University Methods for mapping genetic mutations
US5196305A (en) * 1989-09-12 1993-03-23 Eastman Kodak Company Diagnostic and amplification methods using primers having thymine at 3' end to overcome primer-target mismatch at the 3' end
ES2264239T3 (es) * 1990-06-27 2006-12-16 Princeton University Complejo de proteinas p53/p90'.
AU664381B2 (en) * 1991-07-19 1995-11-16 Upstate Biotechnology, Inc. Method for detection of mutations
WO1993022457A1 (fr) * 1992-04-24 1993-11-11 Massachusetts Institute Of Technology Criblage servant a detecter une variation genetique
US5874212A (en) * 1993-05-13 1999-02-23 Thomas Jefferson University Detection of single base mutations and other variations in double stranded DNA by conformation-sensitive gel electrophoresis
US5851770A (en) * 1994-04-25 1998-12-22 Variagenics, Inc. Detection of mismatches by resolvase cleavage using a magnetic bead support
US20030104361A1 (en) 1997-09-29 2003-06-05 Susan Weininger Method of detection of nucleic acids with a specific sequence composition
US5871902A (en) * 1994-12-09 1999-02-16 The Gene Pool, Inc. Sequence-specific detection of nucleic acid hybrids using a DNA-binding molecule or assembly capable of discriminating perfect hybrids from non-perfect hybrids
AU4745896A (en) * 1995-01-09 1996-07-31 Ambion, Inc. Methods and compositions for use in cleavage and detection of base pair mismatches in double-stranded nucleic acids
US5891629A (en) * 1995-09-28 1999-04-06 Ambion, Inc. Compositions for improving RNase cleavage of base pair mismatches in double-stranded nucleic acids
DE19600362C2 (de) * 1996-01-08 1998-11-12 Wolf Prof Dr Bertling Verfahren zur Erfassung und Quantifizierung von Nucleinsäure-Molekülen
US6080544A (en) * 1998-02-13 2000-06-27 Ohio State University Methods for identifying nucleic acid mutations using mismatch modification
US6723548B2 (en) 2000-05-23 2004-04-20 Board Of Regents, The University Of Texas System DNA repair polypeptides and methods of use
US7141371B2 (en) * 2002-09-06 2006-11-28 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon Methods for detecting and localizing DNA mutations by microarray
WO2005061728A1 (fr) * 2003-12-16 2005-07-07 Institut Curie Methodes et compositions pour mettre en evidence des mutations dans des acides nucleiques
AU2006244042B2 (en) * 2005-05-10 2010-07-29 State Of Oregon Acting By & Through The State Board Of Higher Education On Behalf Of The University Of Oregon Methods of mapping polymorphisms and polymorphism microarrays

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3315116A1 (de) * 1983-03-23 1984-09-27 Europäische Atomgemeinschaft (EURATOM), Luxembourg Verfahren zur direkten bestimmung apurinischer und apyrimidinischer stellen in dna

Also Published As

Publication number Publication date
GB8620244D0 (en) 1986-10-01
JPS62158499A (ja) 1987-07-14
DE3629190A1 (de) 1987-03-05
GB2179735B (en) 1989-12-13
CA1286618C (fr) 1991-07-23
FR2586705A1 (fr) 1987-03-06
BE905348A (fr) 1987-03-02
GB2179735A (en) 1987-03-11
US4794075A (en) 1988-12-27

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Legal Events

Date Code Title Description
ST Notification of lapse
CP Supplementary protection certificate (spc) filed

Free format text: 93C0068, 931223

CR Request for supplementary protection certificate laid open to the public (eec regulation of 18 june 1992)

Free format text: 93C0068, 931223

CR Request for supplementary protection certificate laid open to the public (eec regulation of 18 june 1992)

Free format text: BO 44/94 PAGE 209:LIRE 2585705 AU LIEU DE 2586705

CY Supplementary certificate of protection granted (eec regulation of 18 june 1992)

Free format text: 93C0068, 931223, EXPIRES:20080727