FR2562088B1 - Vecteurs d'expression de l'hirudine, cellules transformees et procede de preparation de l'hirudine - Google Patents

Vecteurs d'expression de l'hirudine, cellules transformees et procede de preparation de l'hirudine

Info

Publication number
FR2562088B1
FR2562088B1 FR8404755A FR8404755A FR2562088B1 FR 2562088 B1 FR2562088 B1 FR 2562088B1 FR 8404755 A FR8404755 A FR 8404755A FR 8404755 A FR8404755 A FR 8404755A FR 2562088 B1 FR2562088 B1 FR 2562088B1
Authority
FR
France
Prior art keywords
hirudin
expression vectors
transformed cells
preparing
hirudin expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8404755A
Other languages
English (en)
Other versions
FR2562088A1 (fr
Inventor
Paul Tolstoshev
Richard Harvey
Michael Courtney
Jean-Pierre Lecocq
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Transgene SA
Original Assignee
Transgene SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR8404755A priority Critical patent/FR2562088B1/fr
Application filed by Transgene SA filed Critical Transgene SA
Priority to JP60501396A priority patent/JP2696316B2/ja
Priority to AT85400598T priority patent/ATE78294T1/de
Priority to DE8585400598T priority patent/DE3586333T2/de
Priority to CA000615690A priority patent/CA1341417C/fr
Priority to CA000477676A priority patent/CA1341414C/fr
Priority to PCT/FR1985/000062 priority patent/WO1985004418A1/fr
Priority to EP85400598A priority patent/EP0158564B1/fr
Publication of FR2562088A1 publication Critical patent/FR2562088A1/fr
Priority to DK198505471A priority patent/DK175217B1/da
Application granted granted Critical
Publication of FR2562088B1 publication Critical patent/FR2562088B1/fr
Priority to US08/481,867 priority patent/US5705355A/en
Priority to US08/500,111 priority patent/US5824505A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
FR8404755A 1984-03-27 1984-03-27 Vecteurs d'expression de l'hirudine, cellules transformees et procede de preparation de l'hirudine Expired FR2562088B1 (fr)

Priority Applications (11)

Application Number Priority Date Filing Date Title
FR8404755A FR2562088B1 (fr) 1984-03-27 1984-03-27 Vecteurs d'expression de l'hirudine, cellules transformees et procede de preparation de l'hirudine
EP85400598A EP0158564B1 (fr) 1984-03-27 1985-03-27 Vecteurs d'expression de l'hirudine, cellules transformées et procédé de préparation de l'hirudine
DE8585400598T DE3586333T2 (de) 1984-03-27 1985-03-27 Expressionsvektoren fuer hirudin, transformierte zellen und verfahren zur herstellung von hirudin.
CA000615690A CA1341417C (fr) 1984-03-27 1985-03-27 Vecteurs d'expression de l'hirudine, cellules transformees et procede de preparation de l'hirudine
CA000477676A CA1341414C (fr) 1984-03-27 1985-03-27 Vecteurs d'expression de l'hirudine, cellules transformees et procede de preparation de l'hirudine
PCT/FR1985/000062 WO1985004418A1 (fr) 1984-03-27 1985-03-27 Vecteurs d'expression de l'hirudine, cellules transformees et procede de preparation de l'hirudine
JP60501396A JP2696316B2 (ja) 1984-03-27 1985-03-27 ヒルジンの発現のためのベクター、形質転換細胞及びヒルジンの製造方法
AT85400598T ATE78294T1 (de) 1984-03-27 1985-03-27 Expressionsvektoren fuer hirudin, transformierte zellen und verfahren zur herstellung von hirudin.
DK198505471A DK175217B1 (da) 1984-03-27 1985-11-26 Hirudinanalog, vektorer til ekspression af hirudinanalog, transformerede celler og fremgangsmåde til fremstilling af hirudinanalog
US08/481,867 US5705355A (en) 1984-03-27 1995-06-07 Hirudin, pharmaceutical compositions comprising it and their use
US08/500,111 US5824505A (en) 1984-03-27 1995-07-10 Vectors, transformed cells and process for the preparation of hirudin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8404755A FR2562088B1 (fr) 1984-03-27 1984-03-27 Vecteurs d'expression de l'hirudine, cellules transformees et procede de preparation de l'hirudine

Publications (2)

Publication Number Publication Date
FR2562088A1 FR2562088A1 (fr) 1985-10-04
FR2562088B1 true FR2562088B1 (fr) 1987-11-13

Family

ID=9302516

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8404755A Expired FR2562088B1 (fr) 1984-03-27 1984-03-27 Vecteurs d'expression de l'hirudine, cellules transformees et procede de preparation de l'hirudine

Country Status (2)

Country Link
JP (1) JP2696316B2 (fr)
FR (1) FR2562088B1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0168342B1 (fr) * 1984-06-14 1991-07-03 Ciba-Geigy Ag Procédé pour la préparation d'inhibiteurs de thrombine
AU648124B2 (en) * 1990-11-08 1994-04-14 Japan Energy Corporation Hirudine mutant, production thereof, anticoagulant, secretory vector, microorganism transformed by said vector, and production of product from said microorganism
JP2573114B2 (ja) * 1991-09-09 1997-01-22 株式会社ジャパンエナジー ヒルジン類分泌生産培養液の処理法
CN117866949A (zh) * 2024-01-15 2024-04-12 南京翌科仪器有限公司 一种基于基因编辑的昆虫生物物质提取方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3342139A1 (de) * 1983-11-22 1985-05-30 Ciba-Geigy Ag, Basel Desulfatohirudine, verfahren zu ihrer herstellung und pharmazeutische mittel

Also Published As

Publication number Publication date
JPS61501609A (ja) 1986-08-07
FR2562088A1 (fr) 1985-10-04
JP2696316B2 (ja) 1998-01-14

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Legal Events

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