FR2555588B1 - Procede de synthese en phase liquide de la somatocrinine et peptides intermediaires - Google Patents

Procede de synthese en phase liquide de la somatocrinine et peptides intermediaires

Info

Publication number
FR2555588B1
FR2555588B1 FR8319058A FR8319058A FR2555588B1 FR 2555588 B1 FR2555588 B1 FR 2555588B1 FR 8319058 A FR8319058 A FR 8319058A FR 8319058 A FR8319058 A FR 8319058A FR 2555588 B1 FR2555588 B1 FR 2555588B1
Authority
FR
France
Prior art keywords
somatocrinine
liquid phase
phase synthesis
intermediate peptides
peptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8319058A
Other languages
English (en)
Other versions
FR2555588A1 (fr
Inventor
Joseph Diaz
Henri Demarne
Romeo Roncucci
Paul-Henry Schmelck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Priority to FR8319058A priority Critical patent/FR2555588B1/fr
Priority to US06/580,287 priority patent/US4581168A/en
Priority to AT84400343T priority patent/ATE30160T1/de
Priority to NZ207205A priority patent/NZ207205A/en
Priority to CA000447826A priority patent/CA1267998A/fr
Priority to EP84400343A priority patent/EP0122818B1/fr
Priority to DK79284A priority patent/DK79284A/da
Priority to IE387/84A priority patent/IE56918B1/xx
Priority to DE8484400343T priority patent/DE3466693D1/de
Priority to NZ22172584A priority patent/NZ221725A/xx
Priority to JP59031335A priority patent/JPS59216859A/ja
Priority to AU24774/84A priority patent/AU574348B2/en
Priority to IL71031A priority patent/IL71031A/xx
Priority to KR1019840000837A priority patent/KR910006284B1/ko
Publication of FR2555588A1 publication Critical patent/FR2555588A1/fr
Priority to US06/807,691 priority patent/US4704450A/en
Application granted granted Critical
Publication of FR2555588B1 publication Critical patent/FR2555588B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
FR8319058A 1983-02-21 1983-11-29 Procede de synthese en phase liquide de la somatocrinine et peptides intermediaires Expired FR2555588B1 (fr)

Priority Applications (15)

Application Number Priority Date Filing Date Title
FR8319058A FR2555588B1 (fr) 1983-11-29 1983-11-29 Procede de synthese en phase liquide de la somatocrinine et peptides intermediaires
US06/580,287 US4581168A (en) 1983-02-21 1984-02-17 Synthesis of hpGRF (Somatocrinin) in liquid phase and intermediate peptides
NZ22172584A NZ221725A (en) 1983-02-21 1984-02-20 Peptide fragments of hp-grf
CA000447826A CA1267998A (fr) 1983-02-21 1984-02-20 Synthese de hpgrf (somotocrinine) dans la phase liquide et peptide intermediaires
EP84400343A EP0122818B1 (fr) 1983-02-21 1984-02-20 Synthèse du hpGRF (Somatocrinine) en phase liquide et peptides intermédiaires
DK79284A DK79284A (da) 1983-02-21 1984-02-20 Syntese af hpgrf (somatocrin) i flydende fase og peptidmellemprodukter
IE387/84A IE56918B1 (en) 1983-02-21 1984-02-20 Synthesis of hpgrf(somatocrinin)in liquid phase and intermediate peptides
DE8484400343T DE3466693D1 (en) 1983-02-21 1984-02-20 Liquid-phase synthesis of hpgrf (somatocrinin) and intermediate peptides
AT84400343T ATE30160T1 (de) 1983-02-21 1984-02-20 Synthese von hpgrf (somatocrinin) in fluessiger phase und mittlere peptide.
NZ207205A NZ207205A (en) 1983-02-21 1984-02-20 Synthesis of hpgrf 1-44 and hpgrf 1-40
JP59031335A JPS59216859A (ja) 1983-02-21 1984-02-21 液相中でのソマトクリニンの合成方法及び中間体ペプチド
AU24774/84A AU574348B2 (en) 1983-02-21 1984-02-21 Synthesis of ph grf (somatocrinine)
IL71031A IL71031A (en) 1983-02-21 1984-02-21 Preparation of somatocrinin and intermediate peptides employed therein
KR1019840000837A KR910006284B1 (ko) 1983-02-21 1984-02-21 hpGRF(소마토크리닌)의 합성 방법
US06/807,691 US4704450A (en) 1983-02-21 1985-12-11 Synthesis of hpGRF(Somatocrinin) in liquid phase and intermediate peptides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8319058A FR2555588B1 (fr) 1983-11-29 1983-11-29 Procede de synthese en phase liquide de la somatocrinine et peptides intermediaires

Publications (2)

Publication Number Publication Date
FR2555588A1 FR2555588A1 (fr) 1985-05-31
FR2555588B1 true FR2555588B1 (fr) 1987-09-11

Family

ID=9294657

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8319058A Expired FR2555588B1 (fr) 1983-02-21 1983-11-29 Procede de synthese en phase liquide de la somatocrinine et peptides intermediaires

Country Status (2)

Country Link
JP (1) JPS59216859A (fr)
FR (1) FR2555588B1 (fr)

Also Published As

Publication number Publication date
JPS59216859A (ja) 1984-12-06
FR2555588A1 (fr) 1985-05-31

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Legal Events

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ST Notification of lapse