FR2544716B1 - Derives acylmercaptoalcanoyles et mercaptoalcanoyles d'aryl- et d'arylalkyl-sulfinyl- ou -sulfonyl-l-prolines utiles notamment comme hypotenseurs, intermediaires pour leur fabrication et medicaments les contenant - Google Patents

Derives acylmercaptoalcanoyles et mercaptoalcanoyles d'aryl- et d'arylalkyl-sulfinyl- ou -sulfonyl-l-prolines utiles notamment comme hypotenseurs, intermediaires pour leur fabrication et medicaments les contenant

Info

Publication number
FR2544716B1
FR2544716B1 FR8406487A FR8406487A FR2544716B1 FR 2544716 B1 FR2544716 B1 FR 2544716B1 FR 8406487 A FR8406487 A FR 8406487A FR 8406487 A FR8406487 A FR 8406487A FR 2544716 B1 FR2544716 B1 FR 2544716B1
Authority
FR
France
Prior art keywords
mercaptoalcanoyl
hydropensors
acylmercaptoalcanoyl
prolines
sulfinyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8406487A
Other languages
English (en)
French (fr)
Other versions
FR2544716A1 (fr
Inventor
John Krapcho
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of FR2544716A1 publication Critical patent/FR2544716A1/fr
Application granted granted Critical
Publication of FR2544716B1 publication Critical patent/FR2544716B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR8406487A 1983-04-25 1984-04-25 Derives acylmercaptoalcanoyles et mercaptoalcanoyles d'aryl- et d'arylalkyl-sulfinyl- ou -sulfonyl-l-prolines utiles notamment comme hypotenseurs, intermediaires pour leur fabrication et medicaments les contenant Expired FR2544716B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US48847783A 1983-04-25 1983-04-25

Publications (2)

Publication Number Publication Date
FR2544716A1 FR2544716A1 (fr) 1984-10-26
FR2544716B1 true FR2544716B1 (fr) 1985-12-06

Family

ID=23939825

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8406487A Expired FR2544716B1 (fr) 1983-04-25 1984-04-25 Derives acylmercaptoalcanoyles et mercaptoalcanoyles d'aryl- et d'arylalkyl-sulfinyl- ou -sulfonyl-l-prolines utiles notamment comme hypotenseurs, intermediaires pour leur fabrication et medicaments les contenant

Country Status (5)

Country Link
JP (1) JPS59205358A (enrdf_load_stackoverflow)
DE (1) DE3415256A1 (enrdf_load_stackoverflow)
FR (1) FR2544716B1 (enrdf_load_stackoverflow)
GB (1) GB2138813B (enrdf_load_stackoverflow)
IT (1) IT1176112B (enrdf_load_stackoverflow)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4316906A (en) * 1978-08-11 1982-02-23 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of substituted prolines
US4307110A (en) * 1980-09-12 1981-12-22 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of 3-substituted proline derivatives
JPS57142962A (en) * 1981-02-28 1982-09-03 Santen Pharmaceut Co Ltd Cyclodextrin clathrate compound of sulfur-containing compound

Also Published As

Publication number Publication date
GB2138813B (en) 1987-02-04
GB2138813A (en) 1984-10-31
JPH0451547B2 (enrdf_load_stackoverflow) 1992-08-19
IT1176112B (it) 1987-08-12
IT8420659A1 (it) 1985-10-20
IT8420659A0 (it) 1984-04-20
JPS59205358A (ja) 1984-11-20
GB8410131D0 (en) 1984-05-31
DE3415256A1 (de) 1984-10-25
FR2544716A1 (fr) 1984-10-26

Similar Documents

Publication Publication Date Title
PT78340A (fr) Procede de preparation de nouveaux derives de la tetrahydroxy- 3',4',5,7-flavone et des compositions pharmaceutiques les contenant
FR2466248B1 (fr) Derives d'agents anti-inflammatoires non steroides, procede de preparation et compositions pharmaceutiques les contenant
FR2567885B1 (fr) Derives 3-aminopropoxyaryliques, leur preparation, leur application comme medicaments et compositions pharmaceutiques les contenant
PT80921A (fr) Procede de preparation de derives d'acylaminomethyl-3-imidazo<1,2-a>pyridines et de compositions pharmaceutiques les contenant
PT87492A (pt) Process for the preparation of benzo ]b" pyrrans and pyranopyridines and pharmaceutical compositions containing them
LU78330A1 (fr) Procede de preparation de nouveaux derives d'hydantoine et de composition pharmaceutique les contenant
PT83896A (fr) Procede pour la preparation de nouveaux conjuges de la vinblas-tine et de ses derives et de compositions pharmaceutiques les contenant
FR2556343B1 (fr) Nouveaux derives d'aminoguanidine, procede pour leur preparation et medicaments les contenant
PT79365B (fr) Procede de preparation de derives d'imidazoline et de compositions pharmaceutiques les contenant
PT78275A (fr) Procede de preparation de nouveaux acides flavone-carboxyliques-4' et de compositions pharmaceutiques les contenant
FR2541280B1 (fr) Nouveaux derives du 1h, 3h-pyrrolo (1,2c) thiazolecarboxamide-7, leur preparation et les medicaments qui les contiennent
FR2446819B1 (fr) Derives 6-alkyles d'acide 1,2-dihydro-2-oxonicotinique et composition pharmaceutique les contenant
MC2050A1 (fr) Derives de benzopyrannols,compositions pharmaceutiques les contenant et procede de fabrication
IT8322648A0 (it) Derivati dell'acido 4-fenil4-osso-buten 2-oico, loro procedimento di preparazione e loro applicazione come prodotti medicinali.
PT82364A (fr) Procede de preparation de derives du nitrofuranne et de compositions pharmaceutiques les contenant
FR2556721B1 (fr) Nouveaux derives de o-mercaptopropanamide d'o amino-acides, leur procede de preparation, leur application comme medicaments et les compositions les renfermant
FR2563519B1 (fr) Derives d'iminothiazolidine, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2544716B1 (fr) Derives acylmercaptoalcanoyles et mercaptoalcanoyles d'aryl- et d'arylalkyl-sulfinyl- ou -sulfonyl-l-prolines utiles notamment comme hypotenseurs, intermediaires pour leur fabrication et medicaments les contenant
FR2598417B1 (fr) Esters d'azoniaspironortropanols, procede pour leur preparation et medicaments les contenant
PT77767B (fr) Procede de preparation de 3',5'-diarabinosides et de compositi-ons pharmaceutiques les contenant
PT82853A (fr) Procede de preparation de nouveaux benzamides et des compositions pharmaceutiques les contenant
PT78272A (fr) Procede de preparation de derives d'(indenyl-2)-2 imidazole et de compositions pharmaceutiques les contenant
FR2563520B1 (fr) Nouveaux derives d'apovincaminol, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2571363B1 (fr) Nouveaux derives substitues en 1 du methoxy-4 trimethyl-2,3,6 benzene, leur procede de preparation et compositions medicamenteuse et cosmetique les contenant
FR2580647B1 (fr) Procede de preparation de derives d'eburnamenine et compositions pharmaceutiques les contenant

Legal Events

Date Code Title Description
ST Notification of lapse