FR2529786A1 - Compositions pharmaceutiques a base de derives de la pyrazolone-5, nouveaux produits et procede de preparation - Google Patents

Compositions pharmaceutiques a base de derives de la pyrazolone-5, nouveaux produits et procede de preparation Download PDF

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Publication number
FR2529786A1
FR2529786A1 FR8212177A FR8212177A FR2529786A1 FR 2529786 A1 FR2529786 A1 FR 2529786A1 FR 8212177 A FR8212177 A FR 8212177A FR 8212177 A FR8212177 A FR 8212177A FR 2529786 A1 FR2529786 A1 FR 2529786A1
Authority
FR
France
Prior art keywords
pyridyl
group
pyrazolone
lower alkyl
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8212177A
Other languages
English (en)
French (fr)
Other versions
FR2529786B1 (OSRAM
Inventor
Francois-Xavier Jarreau
Jean-Jacques Koenig
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nativelle SA Ets
Original Assignee
Nativelle SA Ets
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nativelle SA Ets filed Critical Nativelle SA Ets
Priority to FR8212177A priority Critical patent/FR2529786A1/fr
Publication of FR2529786A1 publication Critical patent/FR2529786A1/fr
Application granted granted Critical
Publication of FR2529786B1 publication Critical patent/FR2529786B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
    • C07D231/20—One oxygen atom attached in position 3 or 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8212177A 1982-07-12 1982-07-12 Compositions pharmaceutiques a base de derives de la pyrazolone-5, nouveaux produits et procede de preparation Granted FR2529786A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR8212177A FR2529786A1 (fr) 1982-07-12 1982-07-12 Compositions pharmaceutiques a base de derives de la pyrazolone-5, nouveaux produits et procede de preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8212177A FR2529786A1 (fr) 1982-07-12 1982-07-12 Compositions pharmaceutiques a base de derives de la pyrazolone-5, nouveaux produits et procede de preparation

Publications (2)

Publication Number Publication Date
FR2529786A1 true FR2529786A1 (fr) 1984-01-13
FR2529786B1 FR2529786B1 (OSRAM) 1985-01-11

Family

ID=9275905

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8212177A Granted FR2529786A1 (fr) 1982-07-12 1982-07-12 Compositions pharmaceutiques a base de derives de la pyrazolone-5, nouveaux produits et procede de preparation

Country Status (1)

Country Link
FR (1) FR2529786A1 (OSRAM)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0183159A3 (de) * 1984-11-28 1987-01-14 Bayer Ag 1-Heteroaryl-4-aryl-pyrazolin-5-one zur Verwendung als Arzneimittel
EP0165448A3 (en) * 1984-05-23 1988-09-07 Bayer Ag 1-heteroaryl-4-aryl-pyrazolin-5-ones
EP0269030A3 (en) * 1986-11-20 1990-11-14 Mitsubishi Chemical Industries Limited Lipid-peroxide formation inhibiting composition and novel compounds useful therefor
EP0467614A1 (en) * 1990-07-17 1992-01-22 Eli Lilly And Company Pyraxolidinone CCK and gastrin antogonists and pharmaceutical formulations thereof
EP0511865A1 (en) * 1991-05-01 1992-11-04 American Home Products Corporation Phenyl pyrazolidinones as bronchodilators and anti-inflammatory agents
US5183825A (en) * 1992-04-07 1993-02-02 American Home Products Corporation 4-arylmethyl-5-alkyl-3H-pyrazol-3-ones and hypoglycemic use
US5300514A (en) * 1990-07-17 1994-04-05 Eli Lilly And Company Pyrazolidinone CCK and gastrin antagonists and pharmaceutical formulations thereof
US5399565A (en) * 1990-07-17 1995-03-21 Eli Lilly And Company Pyrazolidinone CCK and gastrin antagonists and pharmaceutical formulations therof
WO1999033813A1 (fr) * 1997-12-29 1999-07-08 Aventis Cropscience S.A.; Derives 3-hydroxy-pyrazole fongicides
WO2004113359A1 (ja) * 2003-06-20 2004-12-29 Kissei Pharmaceutical Co., Ltd. ピラゾール誘導体、それを含有する医薬組成物及びその製造中間体
JPWO2004031203A1 (ja) * 2002-10-04 2007-08-23 キッセイ薬品工業株式会社 ピラゾール誘導体、それを含有する医薬組成物、その医薬用途及びその製造中間体

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2167997A1 (OSRAM) * 1972-01-14 1973-08-24 Nativelle Sa Ets
EP0007019A1 (de) * 1978-06-29 1980-01-23 Kali-Chemie Pharma GmbH Neue 5-Phenylpyrazol-Derivate und ihre Salze; Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2167997A1 (OSRAM) * 1972-01-14 1973-08-24 Nativelle Sa Ets
EP0007019A1 (de) * 1978-06-29 1980-01-23 Kali-Chemie Pharma GmbH Neue 5-Phenylpyrazol-Derivate und ihre Salze; Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0165448A3 (en) * 1984-05-23 1988-09-07 Bayer Ag 1-heteroaryl-4-aryl-pyrazolin-5-ones
EP0183159A3 (de) * 1984-11-28 1987-01-14 Bayer Ag 1-Heteroaryl-4-aryl-pyrazolin-5-one zur Verwendung als Arzneimittel
EP0269030A3 (en) * 1986-11-20 1990-11-14 Mitsubishi Chemical Industries Limited Lipid-peroxide formation inhibiting composition and novel compounds useful therefor
US5399565A (en) * 1990-07-17 1995-03-21 Eli Lilly And Company Pyrazolidinone CCK and gastrin antagonists and pharmaceutical formulations therof
EP0467614A1 (en) * 1990-07-17 1992-01-22 Eli Lilly And Company Pyraxolidinone CCK and gastrin antogonists and pharmaceutical formulations thereof
US5643926A (en) * 1990-07-17 1997-07-01 Eli Lilly And Company Pyrazolidinone CCK and gastrin antagonists and pharmaceutical formulations thereof
US5300514A (en) * 1990-07-17 1994-04-05 Eli Lilly And Company Pyrazolidinone CCK and gastrin antagonists and pharmaceutical formulations thereof
EP0511865A1 (en) * 1991-05-01 1992-11-04 American Home Products Corporation Phenyl pyrazolidinones as bronchodilators and anti-inflammatory agents
US5183825A (en) * 1992-04-07 1993-02-02 American Home Products Corporation 4-arylmethyl-5-alkyl-3H-pyrazol-3-ones and hypoglycemic use
WO1999033813A1 (fr) * 1997-12-29 1999-07-08 Aventis Cropscience S.A.; Derives 3-hydroxy-pyrazole fongicides
JPWO2004031203A1 (ja) * 2002-10-04 2007-08-23 キッセイ薬品工業株式会社 ピラゾール誘導体、それを含有する医薬組成物、その医薬用途及びその製造中間体
EP1550668A4 (en) * 2002-10-04 2008-10-01 Kissei Pharmaceutical PYRAZOLE DERIVATIVE, MEDICINAL COMPOSITION COMPRISING THE DERIVATIVE, MEDICINAL USE THEREOF, AND INTERMEDIATE ENTERING THE PRODUCTION THEREOF
US7576063B2 (en) 2002-10-04 2009-08-18 Kissei Pharmaceutical Co., Ltd. Pyrazole derivative, medicinal composition containing the same, medicinal use thereof and intermediate in producing the same
JP4530855B2 (ja) * 2002-10-04 2010-08-25 キッセイ薬品工業株式会社 ピラゾール誘導体、それを含有する医薬組成物、その医薬用途及びその製造中間体
US7888487B2 (en) 2002-10-04 2011-02-15 Kissei Pharmaceutical Co., Ltd. Pyrazole derivative, medicinal composition containing the same, medicinal use thereof and intermediate in producing the same
WO2004113359A1 (ja) * 2003-06-20 2004-12-29 Kissei Pharmaceutical Co., Ltd. ピラゾール誘導体、それを含有する医薬組成物及びその製造中間体

Also Published As

Publication number Publication date
FR2529786B1 (OSRAM) 1985-01-11

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