FR2524470B1 - Complexes organometalliques de n-cyclohexyl-piperazino-acetamides ou -propionamides, preparation et utilisation de ces substances comme medicaments-tampons pour combattre des ulceres et la formation de secretions - Google Patents

Complexes organometalliques de n-cyclohexyl-piperazino-acetamides ou -propionamides, preparation et utilisation de ces substances comme medicaments-tampons pour combattre des ulceres et la formation de secretions

Info

Publication number
FR2524470B1
FR2524470B1 FR8221529A FR8221529A FR2524470B1 FR 2524470 B1 FR2524470 B1 FR 2524470B1 FR 8221529 A FR8221529 A FR 8221529A FR 8221529 A FR8221529 A FR 8221529A FR 2524470 B1 FR2524470 B1 FR 2524470B1
Authority
FR
France
Prior art keywords
ulceres
propionamides
acetamides
piperazino
combat
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8221529A
Other languages
English (en)
Other versions
FR2524470A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CORVI CAMILLO SpA
Original Assignee
CORVI CAMILLO SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CORVI CAMILLO SpA filed Critical CORVI CAMILLO SpA
Publication of FR2524470A1 publication Critical patent/FR2524470A1/fr
Application granted granted Critical
Publication of FR2524470B1 publication Critical patent/FR2524470B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
    • C07C59/10—Polyhydroxy carboxylic acids
    • C07C59/105—Polyhydroxy carboxylic acids having five or more carbon atoms, e.g. aldonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/06—Aluminium compounds
    • C07F5/069—Aluminium compounds without C-aluminium linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8221529A 1982-04-05 1982-12-22 Complexes organometalliques de n-cyclohexyl-piperazino-acetamides ou -propionamides, preparation et utilisation de ces substances comme medicaments-tampons pour combattre des ulceres et la formation de secretions Expired FR2524470B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20583/82A IT1150759B (it) 1982-04-05 1982-04-05 Complessi organometallici di n-cicloesil-piperazino-acetammidi o propionammidi, loro preparazione e impiego come farmaci antiulcera-antisecretivi-tamponanti

Publications (2)

Publication Number Publication Date
FR2524470A1 FR2524470A1 (fr) 1983-10-07
FR2524470B1 true FR2524470B1 (fr) 1985-10-25

Family

ID=11169140

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8221529A Expired FR2524470B1 (fr) 1982-04-05 1982-12-22 Complexes organometalliques de n-cyclohexyl-piperazino-acetamides ou -propionamides, preparation et utilisation de ces substances comme medicaments-tampons pour combattre des ulceres et la formation de secretions

Country Status (8)

Country Link
US (1) US4495186A (fr)
JP (1) JPS58177998A (fr)
CA (1) CA1210008A (fr)
DE (1) DE3310584A1 (fr)
ES (1) ES518901A0 (fr)
FR (1) FR2524470B1 (fr)
GB (1) GB2117756B (fr)
IT (1) IT1150759B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3218394B2 (ja) * 1999-09-03 2001-10-15 西川ゴム工業株式会社 自動車ドア下部のシール構造
EP3399014B1 (fr) * 2009-01-30 2020-02-26 Ecolab USA Inc. Mise au point d'un adjuvant à base d'hydroxycarboxylate d'aluminium
US8202830B2 (en) 2009-01-30 2012-06-19 Ecolab Usa Inc. Development of an aluminum hydroxydicarboxylate builder
TW201113280A (en) 2009-07-03 2011-04-16 Nensius Res As Aminoalkamides for use in the treatment of inflammatory, degenerative or demyelinating diseases of the CNS
US8536106B2 (en) 2010-04-14 2013-09-17 Ecolab Usa Inc. Ferric hydroxycarboxylate as a builder

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB779504A (en) * 1954-03-11 1957-07-24 American Cyanamid Co Tetracycline antibiotic complexes
US2910493A (en) * 1955-12-28 1959-10-27 J W Ayers & Co Hydroxy-, alkoxy-aluminum salts of aliphatic amino acids
US3542919A (en) * 1956-06-04 1970-11-24 Wickhen Products Inc Astringent alkali metal aluminum complexes of hydroxy acids
GB1086502A (en) * 1964-07-17 1967-10-11 Rech S Scient Et D Expl De Mar New organometallic or organoboron complexes of tris-(hydroxymethyl) amino-methane and process for preparing the same
US3629229A (en) * 1969-02-27 1971-12-21 Chatten Drug & Chem Co Water soluble basic aluminum polyhydroxyl hydrocarbon complexes
GB1397407A (en) * 1971-07-06 1975-06-11 Hardman & Holden Ltd Aluminium containing pharmaceutical compounds
CH619960A5 (en) * 1974-05-22 1980-10-31 Scharper Spa Process for the preparation of tris(hydroxymethyl)-aminomethane-gluconate dihydroxy-aluminate
IT1043871B (it) * 1974-05-22 1980-02-29 Scharper Spa Procedimento di preparazione industriale di tris idhossimeil aminometan gluconato diiurossi alluminato
IT1054961B (it) * 1976-01-23 1981-11-30 Corvi Camillo Spa Derivati della piperazina adatti come agenti anti ulcera
IT1081804B (it) * 1977-06-07 1985-05-21 Scharper Spa Procedimento di preparazione di tris (idrossimetil)-aminometan-lattato-diidrossialluminato

Also Published As

Publication number Publication date
US4495186A (en) 1985-01-22
CA1210008A (fr) 1986-08-19
JPS58177998A (ja) 1983-10-18
IT8220583A0 (it) 1982-04-05
GB2117756A (en) 1983-10-19
DE3310584A1 (de) 1983-10-13
ES8402593A1 (es) 1984-03-01
IT1150759B (it) 1986-12-17
DE3310584C2 (fr) 1987-07-09
ES518901A0 (es) 1984-03-01
FR2524470A1 (fr) 1983-10-07
GB2117756B (en) 1986-07-02

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Legal Events

Date Code Title Description
ST Notification of lapse