FR2517679B1 - - Google Patents
Info
- Publication number
- FR2517679B1 FR2517679B1 FR8122643A FR8122643A FR2517679B1 FR 2517679 B1 FR2517679 B1 FR 2517679B1 FR 8122643 A FR8122643 A FR 8122643A FR 8122643 A FR8122643 A FR 8122643A FR 2517679 B1 FR2517679 B1 FR 2517679B1
- Authority
- FR
- France
- Prior art keywords
- methyl
- represents hydrogen
- hydrogen
- methoxy
- possess
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000001257 hydrogen Substances 0.000 abstract 5
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- 230000000496 anti-anoxic effect Effects 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 239000000460 chlorine Chemical group 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/16—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Hospice & Palliative Care (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Revetment (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Non-Reversible Transmitting Devices (AREA)
- Glass Compositions (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Priority Applications (18)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8122643A FR2517679A1 (fr) | 1981-12-03 | 1981-12-03 | Derives de diaza-3,7a cyclohepta (j,k) fluorenes, leur preparation et leur application en therapeutique |
| DE8282402172T DE3268605D1 (en) | 1981-12-03 | 1982-11-29 | 3,7a-diazacyclohepta(j,k)fluorene derivatives, their preparation and therapeutical use |
| EP82402172A EP0082040B1 (fr) | 1981-12-03 | 1982-11-29 | Dérivés de diaza-3,7a cyclohepta(j,k)fluorènes, leur préparation et leur application en thérapeutique |
| AT82402172T ATE17485T1 (de) | 1981-12-03 | 1982-11-29 | 3,7a-diazacyclohepta(j,k)fluorenderivate, ihre herstellung und ihre therapeutische verwendung. |
| PT75925A PT75925B (fr) | 1981-12-03 | 1982-12-02 | Procede de preparation de derives de diaza-3,7a cyclohepta <j,k>fluorenes et de compositions pharmaceutiques les contenant |
| HU828374A HU186180B (en) | 1981-12-03 | 1982-12-02 | Process for producing 3,7a-diaza-cyclohepta-bracket-j,k-bracket closed-fluorene derivatives and pharmaceutical compositions containing them |
| GR69964A GR77848B (forum.php) | 1981-12-03 | 1982-12-02 | |
| AU91076/82A AU553493B2 (en) | 1981-12-03 | 1982-12-02 | 3,7alpha-diazacyclohepta(j,k)fluoriene derivatives |
| ES517874A ES8401488A1 (es) | 1981-12-03 | 1982-12-02 | Procedimiento de preparacion de derivados de diaza-3,7a-cicloherta-(j,k)-fluorenos. |
| US06/446,368 US4503058A (en) | 1981-12-03 | 1982-12-02 | Therapeutically useful 3,7a-diazacyclohepta[j,k]fluorene derivatives |
| IL67400A IL67400A (en) | 1981-12-03 | 1982-12-02 | Octahydro-3,7a-diazacyclohepta(j,k)fluorene derivatives,their preparation and pharmaceutical compositions containing them |
| NO824040A NO824040L (no) | 1981-12-03 | 1982-12-02 | Fremgangsmaate for fremstilling av diaza-cykloheptafluorener |
| CA000416847A CA1196329A (en) | 1981-12-03 | 1982-12-02 | 3,7a-diazacyclohepta¬j,k|fluorene derivatives |
| NZ202688A NZ202688A (en) | 1981-12-03 | 1982-12-02 | 3,7a-diazacyclohepta(j,k,)fluorene derivatives and pharmaceutical compositions |
| DK535082A DK535082A (da) | 1981-12-03 | 1982-12-02 | Diaza-3,7a-cyclohepten(j,k)fluorener og fremgangsmaade til fremstilling deraf |
| FI824155A FI71321C (fi) | 1981-12-03 | 1982-12-02 | Foerfarande foer framstaellning av terapeutiskt anvaendbara 1,,3,3a,4,5,6,7-oktahydro-3,7a-diazacyklohepta/j,k/fluorene r |
| ZA828877A ZA828877B (en) | 1981-12-03 | 1982-12-02 | Therapeutically useful 3,7a-diazacyclohepta(j,k)fluorene derivatives |
| JP57213239A JPS58109487A (ja) | 1981-12-03 | 1982-12-03 | 新規ジアザシクロヘプタフルオレン誘導体 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8122643A FR2517679A1 (fr) | 1981-12-03 | 1981-12-03 | Derives de diaza-3,7a cyclohepta (j,k) fluorenes, leur preparation et leur application en therapeutique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2517679A1 FR2517679A1 (fr) | 1983-06-10 |
| FR2517679B1 true FR2517679B1 (forum.php) | 1984-01-27 |
Family
ID=9264634
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8122643A Granted FR2517679A1 (fr) | 1981-12-03 | 1981-12-03 | Derives de diaza-3,7a cyclohepta (j,k) fluorenes, leur preparation et leur application en therapeutique |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4503058A (forum.php) |
| EP (1) | EP0082040B1 (forum.php) |
| JP (1) | JPS58109487A (forum.php) |
| AT (1) | ATE17485T1 (forum.php) |
| AU (1) | AU553493B2 (forum.php) |
| CA (1) | CA1196329A (forum.php) |
| DE (1) | DE3268605D1 (forum.php) |
| DK (1) | DK535082A (forum.php) |
| ES (1) | ES8401488A1 (forum.php) |
| FI (1) | FI71321C (forum.php) |
| FR (1) | FR2517679A1 (forum.php) |
| GR (1) | GR77848B (forum.php) |
| HU (1) | HU186180B (forum.php) |
| IL (1) | IL67400A (forum.php) |
| NO (1) | NO824040L (forum.php) |
| NZ (1) | NZ202688A (forum.php) |
| PT (1) | PT75925B (forum.php) |
| ZA (1) | ZA828877B (forum.php) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4665183A (en) * | 1985-12-20 | 1987-05-12 | American Home Products Corp. | Process for preparing 6,7,8,9-tetrahydro-10-methylpyrido[1,2-a]indol-9-amines and derivatives thereof useful for the treatment of cognitive impairments |
| US4624954A (en) * | 1985-12-20 | 1986-11-25 | American Home Products Corporation | 6,7,8,9-tetrahydro-10-methylpyrido[1,2-a]indol-9-amines and derivatives thereof, useful for the treatment of cognitive impairments |
| CA2027814C (en) * | 1989-10-20 | 1996-07-30 | Ryuji Ueno | Treatment of hepatobiliary disease with 15-keto-prostaglandin compounds |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DD129791A5 (de) * | 1976-04-13 | 1978-02-08 | Synthelabo | Verfahren zur herstellung von naphtyridinderivaten |
| US4228168A (en) * | 1978-11-22 | 1980-10-14 | Tanabe Seiyaku Co., Ltd. | Azepino [1,2,3-lm]-β-carboline compounds and pharmaceutical composition thereof |
| JPS55161389A (en) * | 1979-06-01 | 1980-12-15 | Ngk Spark Plug Co | Method of connecting porcelain insulator to fitting |
-
1981
- 1981-12-03 FR FR8122643A patent/FR2517679A1/fr active Granted
-
1982
- 1982-11-29 DE DE8282402172T patent/DE3268605D1/de not_active Expired
- 1982-11-29 EP EP82402172A patent/EP0082040B1/fr not_active Expired
- 1982-11-29 AT AT82402172T patent/ATE17485T1/de active
- 1982-12-02 AU AU91076/82A patent/AU553493B2/en not_active Ceased
- 1982-12-02 CA CA000416847A patent/CA1196329A/en not_active Expired
- 1982-12-02 ZA ZA828877A patent/ZA828877B/xx unknown
- 1982-12-02 HU HU828374A patent/HU186180B/hu unknown
- 1982-12-02 ES ES517874A patent/ES8401488A1/es not_active Expired
- 1982-12-02 IL IL67400A patent/IL67400A/xx unknown
- 1982-12-02 GR GR69964A patent/GR77848B/el unknown
- 1982-12-02 NO NO824040A patent/NO824040L/no unknown
- 1982-12-02 FI FI824155A patent/FI71321C/fi not_active IP Right Cessation
- 1982-12-02 PT PT75925A patent/PT75925B/pt unknown
- 1982-12-02 NZ NZ202688A patent/NZ202688A/en unknown
- 1982-12-02 US US06/446,368 patent/US4503058A/en not_active Expired - Fee Related
- 1982-12-02 DK DK535082A patent/DK535082A/da not_active Application Discontinuation
- 1982-12-03 JP JP57213239A patent/JPS58109487A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA1196329A (en) | 1985-11-05 |
| HU186180B (en) | 1985-06-28 |
| NZ202688A (en) | 1985-01-31 |
| FR2517679A1 (fr) | 1983-06-10 |
| DE3268605D1 (en) | 1986-02-27 |
| FI71321C (fi) | 1986-12-19 |
| PT75925A (fr) | 1983-01-01 |
| FI824155L (fi) | 1983-06-04 |
| EP0082040B1 (fr) | 1986-01-15 |
| PT75925B (fr) | 1985-12-20 |
| FI824155A0 (fi) | 1982-12-02 |
| JPS58109487A (ja) | 1983-06-29 |
| ES517874A0 (es) | 1983-12-01 |
| FI71321B (fi) | 1986-09-09 |
| ZA828877B (en) | 1983-09-28 |
| US4503058A (en) | 1985-03-05 |
| IL67400A0 (en) | 1983-05-15 |
| DK535082A (da) | 1983-06-04 |
| AU553493B2 (en) | 1986-07-17 |
| ATE17485T1 (de) | 1986-02-15 |
| IL67400A (en) | 1985-07-31 |
| AU9107682A (en) | 1983-06-09 |
| NO824040L (no) | 1983-06-06 |
| GR77848B (forum.php) | 1984-09-25 |
| EP0082040A1 (fr) | 1983-06-22 |
| ES8401488A1 (es) | 1983-12-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |