FR2513264A1 - Procede d'agitation de cultures cellulaires et dispositif pour sa mise en oeuvre - Google Patents
Procede d'agitation de cultures cellulaires et dispositif pour sa mise en oeuvre Download PDFInfo
- Publication number
- FR2513264A1 FR2513264A1 FR8117857A FR8117857A FR2513264A1 FR 2513264 A1 FR2513264 A1 FR 2513264A1 FR 8117857 A FR8117857 A FR 8117857A FR 8117857 A FR8117857 A FR 8117857A FR 2513264 A1 FR2513264 A1 FR 2513264A1
- Authority
- FR
- France
- Prior art keywords
- inert fluid
- agitation
- suspension
- fluid
- inert
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012530 fluid Substances 0.000 title claims abstract description 31
- 238000013019 agitation Methods 0.000 title claims abstract description 17
- 239000000725 suspension Substances 0.000 title abstract description 6
- 239000006285 cell suspension Substances 0.000 title 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 10
- 239000007788 liquid Substances 0.000 claims abstract description 7
- 230000010261 cell growth Effects 0.000 claims abstract description 4
- 239000000126 substance Substances 0.000 claims abstract description 4
- 238000000034 method Methods 0.000 claims description 21
- 238000004113 cell culture Methods 0.000 claims description 17
- 230000033001 locomotion Effects 0.000 claims description 11
- 238000012544 monitoring process Methods 0.000 claims 1
- 238000005086 pumping Methods 0.000 abstract 3
- 239000006096 absorbing agent Substances 0.000 abstract 1
- 238000004886 process control Methods 0.000 abstract 1
- 239000001963 growth medium Substances 0.000 description 17
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 12
- 239000001301 oxygen Substances 0.000 description 12
- 229910052760 oxygen Inorganic materials 0.000 description 12
- 238000003756 stirring Methods 0.000 description 9
- 238000005273 aeration Methods 0.000 description 4
- 230000001105 regulatory effect Effects 0.000 description 4
- 244000005700 microbiome Species 0.000 description 3
- 239000002609 medium Substances 0.000 description 2
- 125000000217 alkyl group Chemical group 0.000 description 1
- 239000012736 aqueous medium Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000003633 blood substitute Substances 0.000 description 1
- 230000005587 bubbling Effects 0.000 description 1
- 239000006143 cell culture medium Substances 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 150000002430 hydrocarbons Chemical class 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 239000002054 inoculum Substances 0.000 description 1
- 238000010907 mechanical stirring Methods 0.000 description 1
- 239000011325 microbead Substances 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- 238000006213 oxygenation reaction Methods 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 229920002545 silicone oil Polymers 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/18—Stationary reactors having moving elements inside
- B01J19/185—Stationary reactors having moving elements inside of the pulsating type
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/02—Stirrer or mobile mixing elements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00049—Controlling or regulating processes
- B01J2219/00177—Controlling or regulating processes controlling the pH
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8117857A FR2513264A1 (fr) | 1981-09-22 | 1981-09-22 | Procede d'agitation de cultures cellulaires et dispositif pour sa mise en oeuvre |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8117857A FR2513264A1 (fr) | 1981-09-22 | 1981-09-22 | Procede d'agitation de cultures cellulaires et dispositif pour sa mise en oeuvre |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2513264A1 true FR2513264A1 (fr) | 1983-03-25 |
| FR2513264B1 FR2513264B1 (cg-RX-API-DMAC7.html) | 1985-03-22 |
Family
ID=9262363
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8117857A Granted FR2513264A1 (fr) | 1981-09-22 | 1981-09-22 | Procede d'agitation de cultures cellulaires et dispositif pour sa mise en oeuvre |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2513264A1 (cg-RX-API-DMAC7.html) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0164813A3 (en) * | 1984-06-14 | 1988-04-27 | Teijin Limited | Method of cultivating animal or plant cells |
| EP0229289A3 (en) * | 1985-12-06 | 1989-02-08 | Teijin Limited | Method of culturing animal cells |
| EP0356724A3 (en) * | 1988-07-29 | 1990-08-22 | Biochem Technology Inc. | Method of increasing the quantity of product produced by fragile cell and tissue cultures |
| EP0387065A3 (en) * | 1989-03-08 | 1991-10-16 | Mitsui Petrochemical Industries, Ltd. | Method for culturing plant tissue, apparatus therefor and method for producing metabolite |
| US5250432A (en) * | 1985-12-06 | 1993-10-05 | Teijin Limited | Method of culturing animal cells |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2177051A1 (cg-RX-API-DMAC7.html) * | 1972-03-23 | 1973-11-02 | Tanabe Seiyaku Co |
-
1981
- 1981-09-22 FR FR8117857A patent/FR2513264A1/fr active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2177051A1 (cg-RX-API-DMAC7.html) * | 1972-03-23 | 1973-11-02 | Tanabe Seiyaku Co |
Non-Patent Citations (2)
| Title |
|---|
| CHEMICAL ABSTRACTS, vol. 95, no. 7, 17 août 1981, page 451, résumé no. 5908v, COLUMBUS, OHIO (US) & Dokl. Akad. Nauk SSSR 1981, 258 (1), 225-8 (Biophys)(Russ.), G.R. IVANITSKII et al.: 'Cultivation of animals cells on liquid perflourocarbons' * |
| CHEMICAL ABSTRACTS, vol. 96, no. 13, 29 mars 1982, page 358, résumé no. 100292x, COLUMBUS, OHIO (US) & perftorirovannye Uglerody Biol. Med. 1980, 98-100 (Russ.), ARKHIPOV, V.V.: 'Cultivation of cells on liquid of fluorocarbon substrates' * |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0164813A3 (en) * | 1984-06-14 | 1988-04-27 | Teijin Limited | Method of cultivating animal or plant cells |
| EP0229289A3 (en) * | 1985-12-06 | 1989-02-08 | Teijin Limited | Method of culturing animal cells |
| EP0480245A1 (en) * | 1985-12-06 | 1992-04-15 | Teijin Limited | Method of culturing animal cells |
| US5250432A (en) * | 1985-12-06 | 1993-10-05 | Teijin Limited | Method of culturing animal cells |
| EP0356724A3 (en) * | 1988-07-29 | 1990-08-22 | Biochem Technology Inc. | Method of increasing the quantity of product produced by fragile cell and tissue cultures |
| EP0387065A3 (en) * | 1989-03-08 | 1991-10-16 | Mitsui Petrochemical Industries, Ltd. | Method for culturing plant tissue, apparatus therefor and method for producing metabolite |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2513264B1 (cg-RX-API-DMAC7.html) | 1985-03-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |