FR2508042B1 - Procede pour preparer le 4-hydroxy-2-methyl-2h-1,2-benzothiazine-3-(n-(2-pyridinyl) carboxamide)-1,1-dioxide, son ester phosphorique et l'ester phosphorique obtenu - Google Patents

Procede pour preparer le 4-hydroxy-2-methyl-2h-1,2-benzothiazine-3-(n-(2-pyridinyl) carboxamide)-1,1-dioxide, son ester phosphorique et l'ester phosphorique obtenu

Info

Publication number
FR2508042B1
FR2508042B1 FR8210411A FR8210411A FR2508042B1 FR 2508042 B1 FR2508042 B1 FR 2508042B1 FR 8210411 A FR8210411 A FR 8210411A FR 8210411 A FR8210411 A FR 8210411A FR 2508042 B1 FR2508042 B1 FR 2508042B1
Authority
FR
France
Prior art keywords
phosphoric ester
benzothiazine
pyridinyl
carboxamide
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8210411A
Other languages
English (en)
Other versions
FR2508042A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ISOM SpA
Original Assignee
ISOM SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT22364/81A external-priority patent/IT1167793B/it
Priority claimed from IT23432/81A external-priority patent/IT1167488B/it
Application filed by ISOM SpA filed Critical ISOM SpA
Publication of FR2508042A1 publication Critical patent/FR2508042A1/fr
Application granted granted Critical
Publication of FR2508042B1 publication Critical patent/FR2508042B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6536—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms
    • C07F9/6544—Six-membered rings
    • C07F9/6547—Six-membered rings condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
FR8210411A 1981-06-17 1982-06-15 Procede pour preparer le 4-hydroxy-2-methyl-2h-1,2-benzothiazine-3-(n-(2-pyridinyl) carboxamide)-1,1-dioxide, son ester phosphorique et l'ester phosphorique obtenu Expired FR2508042B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT22364/81A IT1167793B (it) 1981-06-17 1981-06-17 Estere fosforico del 4-idrossi-2-metil-2h-1,2-benzotiazina-3(n-(2-piridil)-carbossamide)-1,1-diossido,suoi sali,procedimenti per ottenerli e preparati farmaceutici che li contengono come principi attivi
IT23432/81A IT1167488B (it) 1981-08-07 1981-08-07 Procedimento per la preparazione del 4-idrossi-2-metil-2h-1,2-benzotiazina-3-(n-(2-piridinil)carbossamide)-1,1-diossido e del suo estere fosforico

Publications (2)

Publication Number Publication Date
FR2508042A1 FR2508042A1 (fr) 1982-12-24
FR2508042B1 true FR2508042B1 (fr) 1985-08-23

Family

ID=26328171

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8210411A Expired FR2508042B1 (fr) 1981-06-17 1982-06-15 Procede pour preparer le 4-hydroxy-2-methyl-2h-1,2-benzothiazine-3-(n-(2-pyridinyl) carboxamide)-1,1-dioxide, son ester phosphorique et l'ester phosphorique obtenu

Country Status (5)

Country Link
US (3) US4474955A (fr)
CH (1) CH658456A5 (fr)
DE (1) DE3221745A1 (fr)
FR (1) FR2508042B1 (fr)
GB (3) GB2104506B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4474955A (en) * 1981-06-17 1984-10-02 Vincenzo Iannella Process for preparing 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-[N-(2-pyridinyl)carboxamide]-1,1-dioxide, and its phosphoric ester
US4460579A (en) * 1983-02-28 1984-07-17 E. R. Squibb & Sons, Inc. Thiazine and thiazepine containing compounds
YU42883B (en) * 1983-10-06 1988-12-31 Krka Novo Mesto Process for the manufacture of n-(2-pyridil)-2-methyl-4-hydroxy-2h-1,2-benzothiazine-3-carboxamide-1,1-dioxide
US5022997A (en) 1989-12-18 1991-06-11 The Graver Company Method for treating aqueous solutions
CN108690078A (zh) * 2017-03-29 2018-10-23 江苏恒瑞医药股份有限公司 一种苯并塞嗪磷酸酯衍生物、其制备方法及其在医药上的应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3591584A (en) * 1968-08-27 1971-07-06 Pfizer Benzothiazine dioxides
NL7200247A (fr) * 1971-01-11 1972-07-13
US3787324A (en) * 1971-03-01 1974-01-22 Warner Lambert Co 4-hydroxy-3-(3-isoxazolocarbamyl)-2h-1,2-benzothiazine 1,dioxides and process for their production
US3704298A (en) * 1971-06-22 1972-11-28 Warner Lambert Co 4-acyloxy-3-(2-isoxazolocarbamyl)-2h-1,2-benzothiazine 1,1-dioxides
US3925371A (en) * 1974-09-23 1975-12-09 Mcneilab Inc Benzothiazine-1,1-dioxides
US3891637A (en) * 1974-10-01 1975-06-24 Pfizer Process for the production of carboxamides of oxo-1,2-benzothiazine-1,1-dioxides
DE2452996A1 (de) * 1974-11-08 1976-05-20 Thomae Gmbh Dr K Neue 4-hydroxy-2h-naphtho- eckige klammer auf 2,1-e eckige klammer zu -1,2thiazin-3-carboxamid-1,1-dioxide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
SE421792B (sv) * 1976-01-12 1982-02-01 Pfizer Forfarande for framstellning av n-(2-pyridyl)-4-hydroxi-2-metyl-2h-1,2-benso-tiazin-3-karboxamid-1,1-dioxid
US4074048A (en) * 1976-05-10 1978-02-14 Warner-Lambert Company Process for the preparation of 4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxides
US4100347A (en) * 1976-06-10 1978-07-11 Pfizer Inc. 3,4-Dihydro-2-methyl-4-oxo-2H-1,2-benzothiazine-3-carboxylic acid-1,1-dioxide
JPS5535050A (en) * 1978-09-04 1980-03-11 Sumitomo Chem Co Ltd Thio- or dithio-phosphoric acid ester, its preparation, and insecticide, miticide and nematicide containing the same
US4309427A (en) * 1981-01-15 1982-01-05 Pfizer Inc. Benzothiazine dioxide derivatives
US4474955A (en) * 1981-06-17 1984-10-02 Vincenzo Iannella Process for preparing 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-[N-(2-pyridinyl)carboxamide]-1,1-dioxide, and its phosphoric ester

Also Published As

Publication number Publication date
GB2145417B (en) 1985-11-06
US4587335A (en) 1986-05-06
GB2104506B (en) 1985-11-06
GB2145724A (en) 1985-04-03
GB2104506A (en) 1983-03-09
FR2508042A1 (fr) 1982-12-24
GB2145724B (en) 1985-10-30
DE3221745A1 (de) 1982-12-30
CH658456A5 (fr) 1986-11-14
US4474955A (en) 1984-10-02
DE3221745C2 (fr) 1991-02-14
US4680405A (en) 1987-07-14
GB2145417A (en) 1985-03-27
GB8423696D0 (en) 1984-10-24
GB8423695D0 (en) 1984-10-24

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Legal Events

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TP Transmission of property
ST Notification of lapse