FR2496891A1 - Methode et appareil d'analyse d'especes ioniques utilisant un milieu de separation chromatographique - Google Patents
Methode et appareil d'analyse d'especes ioniques utilisant un milieu de separation chromatographique Download PDFInfo
- Publication number
- FR2496891A1 FR2496891A1 FR8104668A FR8104668A FR2496891A1 FR 2496891 A1 FR2496891 A1 FR 2496891A1 FR 8104668 A FR8104668 A FR 8104668A FR 8104668 A FR8104668 A FR 8104668A FR 2496891 A1 FR2496891 A1 FR 2496891A1
- Authority
- FR
- France
- Prior art keywords
- ion
- column
- ionic species
- ions
- complementary
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 title claims abstract description 44
- 238000013375 chromatographic separation Methods 0.000 title claims abstract description 14
- 150000001450 anions Chemical class 0.000 claims abstract description 24
- 150000001768 cations Chemical class 0.000 claims abstract description 8
- 238000004445 quantitative analysis Methods 0.000 claims abstract description 6
- 150000002500 ions Chemical class 0.000 claims description 110
- 230000000295 complement effect Effects 0.000 claims description 56
- 239000011347 resin Substances 0.000 claims description 48
- 229920005989 resin Polymers 0.000 claims description 48
- 238000005342 ion exchange Methods 0.000 claims description 39
- 239000012071 phase Substances 0.000 claims description 33
- 239000003480 eluent Substances 0.000 claims description 29
- 230000002441 reversible effect Effects 0.000 claims description 29
- 150000001875 compounds Chemical class 0.000 claims description 18
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 16
- 230000002209 hydrophobic effect Effects 0.000 claims description 15
- 239000003153 chemical reaction reagent Substances 0.000 claims description 14
- 238000001179 sorption measurement Methods 0.000 claims description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical group O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
- 239000007791 liquid phase Substances 0.000 claims description 10
- 239000000758 substrate Substances 0.000 claims description 9
- 239000000377 silicon dioxide Substances 0.000 claims description 8
- -1 alkylammonium ion Chemical class 0.000 claims description 7
- 150000002894 organic compounds Chemical class 0.000 claims description 7
- 239000004094 surface-active agent Substances 0.000 claims description 7
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 claims description 6
- 150000002430 hydrocarbons Chemical group 0.000 claims description 6
- 125000000129 anionic group Chemical group 0.000 claims description 5
- 239000003456 ion exchange resin Substances 0.000 claims description 5
- 229920003303 ion-exchange polymer Polymers 0.000 claims description 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 claims description 4
- BTBUEUYNUDRHOZ-UHFFFAOYSA-N Borate Chemical compound [O-]B([O-])[O-] BTBUEUYNUDRHOZ-UHFFFAOYSA-N 0.000 claims description 3
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims description 3
- 230000003111 delayed effect Effects 0.000 claims description 2
- 229910052739 hydrogen Inorganic materials 0.000 claims description 2
- 239000001257 hydrogen Substances 0.000 claims description 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 238000005341 cation exchange Methods 0.000 claims 1
- ZCDOYSPFYFSLEW-UHFFFAOYSA-N chromate(2-) Chemical compound [O-][Cr]([O-])(=O)=O ZCDOYSPFYFSLEW-UHFFFAOYSA-N 0.000 claims 1
- 125000000962 organic group Chemical group 0.000 claims 1
- 230000001105 regulatory effect Effects 0.000 claims 1
- 238000004458 analytical method Methods 0.000 abstract description 16
- 150000001767 cationic compounds Chemical class 0.000 abstract description 5
- 230000001629 suppression Effects 0.000 abstract description 4
- 150000002892 organic cations Chemical class 0.000 abstract description 3
- 238000000926 separation method Methods 0.000 description 28
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 18
- VDZOOKBUILJEDG-UHFFFAOYSA-M tetrabutylammonium hydroxide Chemical compound [OH-].CCCC[N+](CCCC)(CCCC)CCCC VDZOOKBUILJEDG-UHFFFAOYSA-M 0.000 description 18
- 230000005526 G1 to G0 transition Effects 0.000 description 14
- 239000007788 liquid Substances 0.000 description 14
- 239000000523 sample Substances 0.000 description 11
- 238000004255 ion exchange chromatography Methods 0.000 description 10
- MYRTYDVEIRVNKP-UHFFFAOYSA-N 1,2-Divinylbenzene Chemical compound C=CC1=CC=CC=C1C=C MYRTYDVEIRVNKP-UHFFFAOYSA-N 0.000 description 8
- 238000001514 detection method Methods 0.000 description 8
- 230000014759 maintenance of location Effects 0.000 description 8
- 239000002253 acid Substances 0.000 description 7
- 230000008901 benefit Effects 0.000 description 7
- 230000007246 mechanism Effects 0.000 description 7
- 230000000717 retained effect Effects 0.000 description 7
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 6
- 238000004190 ion pair chromatography Methods 0.000 description 6
- 125000000217 alkyl group Chemical group 0.000 description 5
- 150000001449 anionic compounds Chemical class 0.000 description 5
- 229910001412 inorganic anion Inorganic materials 0.000 description 5
- 239000000203 mixture Substances 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- 230000015572 biosynthetic process Effects 0.000 description 4
- 125000004432 carbon atom Chemical group C* 0.000 description 4
- 238000004587 chromatography analysis Methods 0.000 description 4
- GPRLSGONYQIRFK-UHFFFAOYSA-N hydron Chemical compound [H+] GPRLSGONYQIRFK-UHFFFAOYSA-N 0.000 description 4
- 229910001411 inorganic cation Inorganic materials 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 229910002651 NO3 Inorganic materials 0.000 description 3
- 239000004793 Polystyrene Substances 0.000 description 3
- 150000007513 acids Chemical class 0.000 description 3
- 239000003945 anionic surfactant Substances 0.000 description 3
- 229920001429 chelating resin Polymers 0.000 description 3
- 229920001577 copolymer Polymers 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 238000012856 packing Methods 0.000 description 3
- 229920001467 poly(styrenesulfonates) Polymers 0.000 description 3
- 229920002223 polystyrene Polymers 0.000 description 3
- 150000003839 salts Chemical class 0.000 description 3
- DZLFLBLQUQXARW-UHFFFAOYSA-N tetrabutylammonium Chemical compound CCCC[N+](CCCC)(CCCC)CCCC DZLFLBLQUQXARW-UHFFFAOYSA-N 0.000 description 3
- HNSDLXPSAYFUHK-UHFFFAOYSA-N 1,4-bis(2-ethylhexyl) sulfosuccinate Chemical compound CCCCC(CC)COC(=O)CC(S(O)(=O)=O)C(=O)OCC(CC)CCCC HNSDLXPSAYFUHK-UHFFFAOYSA-N 0.000 description 2
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 description 2
- 229910019142 PO4 Inorganic materials 0.000 description 2
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 239000003957 anion exchange resin Substances 0.000 description 2
- 239000003729 cation exchange resin Substances 0.000 description 2
- 125000002091 cationic group Chemical group 0.000 description 2
- 238000010494 dissociation reaction Methods 0.000 description 2
- 230000005593 dissociations Effects 0.000 description 2
- 238000004090 dissolution Methods 0.000 description 2
- 238000011067 equilibration Methods 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000004128 high performance liquid chromatography Methods 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- VLTRZXGMWDSKGL-UHFFFAOYSA-M perchlorate Inorganic materials [O-]Cl(=O)(=O)=O VLTRZXGMWDSKGL-UHFFFAOYSA-M 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
- 238000004366 reverse phase liquid chromatography Methods 0.000 description 2
- 229910001220 stainless steel Inorganic materials 0.000 description 2
- 239000010935 stainless steel Substances 0.000 description 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 1
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 description 1
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- XFXPMWWXUTWYJX-UHFFFAOYSA-N Cyanide Chemical compound N#[C-] XFXPMWWXUTWYJX-UHFFFAOYSA-N 0.000 description 1
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 description 1
- 238000004566 IR spectroscopy Methods 0.000 description 1
- 238000005481 NMR spectroscopy Methods 0.000 description 1
- IOVCWXUNBOPUCH-UHFFFAOYSA-M Nitrite anion Chemical compound [O-]N=O IOVCWXUNBOPUCH-UHFFFAOYSA-M 0.000 description 1
- ZMZDMBWJUHKJPS-UHFFFAOYSA-M Thiocyanate anion Chemical compound [S-]C#N ZMZDMBWJUHKJPS-UHFFFAOYSA-M 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 125000001931 aliphatic group Chemical group 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 239000000908 ammonium hydroxide Substances 0.000 description 1
- 239000008346 aqueous phase Substances 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 150000001540 azides Chemical class 0.000 description 1
- 235000013361 beverage Nutrition 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- SXDBWCPKPHAZSM-UHFFFAOYSA-M bromate Inorganic materials [O-]Br(=O)=O SXDBWCPKPHAZSM-UHFFFAOYSA-M 0.000 description 1
- SXDBWCPKPHAZSM-UHFFFAOYSA-N bromic acid Chemical compound OBr(=O)=O SXDBWCPKPHAZSM-UHFFFAOYSA-N 0.000 description 1
- 150000007942 carboxylates Chemical group 0.000 description 1
- 239000003093 cationic surfactant Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000007385 chemical modification Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- XTEGARKTQYYJKE-UHFFFAOYSA-M chlorate Inorganic materials [O-]Cl(=O)=O XTEGARKTQYYJKE-UHFFFAOYSA-M 0.000 description 1
- 125000004218 chloromethyl group Chemical group [H]C([H])(Cl)* 0.000 description 1
- 230000002860 competitive effect Effects 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000012217 deletion Methods 0.000 description 1
- 230000037430 deletion Effects 0.000 description 1
- 238000003795 desorption Methods 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 230000002542 deteriorative effect Effects 0.000 description 1
- XPPKVPWEQAFLFU-UHFFFAOYSA-J diphosphate(4-) Chemical compound [O-]P([O-])(=O)OP([O-])([O-])=O XPPKVPWEQAFLFU-UHFFFAOYSA-J 0.000 description 1
- 235000011180 diphosphates Nutrition 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 125000003438 dodecyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 238000010828 elution Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- YAGKRVSRTSUGEY-UHFFFAOYSA-N ferricyanide Chemical compound [Fe+3].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-] YAGKRVSRTSUGEY-UHFFFAOYSA-N 0.000 description 1
- 235000015203 fruit juice Nutrition 0.000 description 1
- 235000019990 fruit wine Nutrition 0.000 description 1
- FYAQQULBLMNGAH-UHFFFAOYSA-N hexane-1-sulfonic acid Chemical compound CCCCCCS(O)(=O)=O FYAQQULBLMNGAH-UHFFFAOYSA-N 0.000 description 1
- 150000002431 hydrogen Chemical class 0.000 description 1
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 description 1
- ZMZDMBWJUHKJPS-UHFFFAOYSA-N hydrogen thiocyanate Natural products SC#N ZMZDMBWJUHKJPS-UHFFFAOYSA-N 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 150000002484 inorganic compounds Chemical class 0.000 description 1
- 229910001410 inorganic ion Inorganic materials 0.000 description 1
- 229910010272 inorganic material Inorganic materials 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 229910052920 inorganic sulfate Inorganic materials 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- ICIWUVCWSCSTAQ-UHFFFAOYSA-M iodate Chemical compound [O-]I(=O)=O ICIWUVCWSCSTAQ-UHFFFAOYSA-M 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
- 229910052753 mercury Inorganic materials 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- SFMJNHNUOVADRW-UHFFFAOYSA-N n-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[h][1,6]naphthyridin-1-yl]-2-methylphenyl]prop-2-enamide Chemical compound C1=C(NC(=O)C=C)C(C)=CC=C1N1C(=O)C=CC2=C1C1=CC(C=3C=CC(NS(C)(=O)=O)=CC=3)=CC=C1N=C2 SFMJNHNUOVADRW-UHFFFAOYSA-N 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 150000007530 organic bases Chemical class 0.000 description 1
- 239000005416 organic matter Substances 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 150000001367 organochlorosilanes Chemical class 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- VLTRZXGMWDSKGL-UHFFFAOYSA-N perchloric acid Chemical compound OCl(=O)(=O)=O VLTRZXGMWDSKGL-UHFFFAOYSA-N 0.000 description 1
- JRKICGRDRMAZLK-UHFFFAOYSA-L peroxydisulfate Chemical compound [O-]S(=O)(=O)OOS([O-])(=O)=O JRKICGRDRMAZLK-UHFFFAOYSA-L 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 239000003361 porogen Substances 0.000 description 1
- 238000004663 powder metallurgy Methods 0.000 description 1
- 230000001376 precipitating effect Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 239000012488 sample solution Substances 0.000 description 1
- 125000000467 secondary amino group Chemical group [H]N([*:1])[*:2] 0.000 description 1
- 238000011896 sensitive detection Methods 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- LXMSZDCAJNLERA-ZHYRCANASA-N spironolactone Chemical compound C([C@@H]1[C@]2(C)CC[C@@H]3[C@@]4(C)CCC(=O)C=C4C[C@H]([C@@H]13)SC(=O)C)C[C@@]21CCC(=O)O1 LXMSZDCAJNLERA-ZHYRCANASA-N 0.000 description 1
- 239000012607 strong cation exchange resin Substances 0.000 description 1
- 125000001273 sulfonato group Chemical group [O-]S(*)(=O)=O 0.000 description 1
- 229910021653 sulphate ion Inorganic materials 0.000 description 1
- 239000002352 surface water Substances 0.000 description 1
- 125000001302 tertiary amino group Chemical group 0.000 description 1
- 150000005622 tetraalkylammonium hydroxides Chemical class 0.000 description 1
- JRMUNVKIHCOMHV-UHFFFAOYSA-M tetrabutylammonium bromide Chemical compound [Br-].CCCC[N+](CCCC)(CCCC)CCCC JRMUNVKIHCOMHV-UHFFFAOYSA-M 0.000 description 1
- DHCDFWKWKRSZHF-UHFFFAOYSA-L thiosulfate(2-) Chemical compound [O-]S([S-])(=O)=O DHCDFWKWKRSZHF-UHFFFAOYSA-L 0.000 description 1
- 125000005208 trialkylammonium group Chemical group 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
- 239000012608 weak cation exchange resin Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/46—Flow patterns using more than one column
- G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
- B01J39/26—Cation exchangers for chromatographic processes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/96—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/96—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange
- G01N2030/965—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange suppressor columns
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12873080A | 1980-03-10 | 1980-03-10 | |
| US06/128,836 US4265634A (en) | 1980-03-10 | 1980-03-10 | Chromatographic separation and quantitative analysis of ionic species |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2496891A1 true FR2496891A1 (fr) | 1982-06-25 |
| FR2496891B1 FR2496891B1 (ref) | 1984-06-29 |
Family
ID=26826891
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8104668A Granted FR2496891A1 (fr) | 1980-03-10 | 1981-03-09 | Methode et appareil d'analyse d'especes ioniques utilisant un milieu de separation chromatographique |
Country Status (4)
| Country | Link |
|---|---|
| AU (1) | AU546009B2 (ref) |
| DE (1) | DE3108924C2 (ref) |
| FR (1) | FR2496891A1 (ref) |
| GB (1) | GB2070964B (ref) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4486312A (en) * | 1983-08-12 | 1984-12-04 | Dionex Corporation | Analysis of liquid streams using tubing with protuberances on its inner wall |
| DE3839035A1 (de) * | 1988-11-18 | 1991-01-31 | Schaper Hans Heinrich | Verfahren zur chromatographischen bestimmung von kationen |
| DE102007016612A1 (de) | 2007-04-05 | 2008-10-09 | BAM Bundesanstalt für Materialforschung und -prüfung | Vorrichtung und Verfahren zur Untersuchung eines heterogenen Materials mittels laserinduzierter Plasmaspektroskopie |
| CN112400109B (zh) * | 2018-07-11 | 2024-07-19 | 沃特世科技公司 | 用于捕集-洗脱混合模式色谱法的色谱系统和方法 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3920397A (en) * | 1973-08-06 | 1975-11-18 | Dow Chemical Co | Apparatus and method for quantitative analysis of ionic species by liquid column chromatography |
| US3925019A (en) * | 1973-08-06 | 1975-12-09 | Dow Chemical Co | Chromatographic analysis of ionic species |
| US4042327A (en) * | 1976-01-15 | 1977-08-16 | Waters Associates, Inc. | Ion-pairing chromatography |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2437600C2 (de) * | 1973-08-06 | 1986-04-24 | Dionex Corp., Sunnyvale, Calif. | Vorrichtung und Verfahren zur quantitativen Analyse ionischer Species durch Flüssigkeitssäulenchromatographie |
-
1981
- 1981-03-02 GB GB8106448A patent/GB2070964B/en not_active Expired
- 1981-03-04 AU AU68049/81A patent/AU546009B2/en not_active Ceased
- 1981-03-09 FR FR8104668A patent/FR2496891A1/fr active Granted
- 1981-03-09 DE DE19813108924 patent/DE3108924C2/de not_active Expired
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3920397A (en) * | 1973-08-06 | 1975-11-18 | Dow Chemical Co | Apparatus and method for quantitative analysis of ionic species by liquid column chromatography |
| US3925019A (en) * | 1973-08-06 | 1975-12-09 | Dow Chemical Co | Chromatographic analysis of ionic species |
| US4042327A (en) * | 1976-01-15 | 1977-08-16 | Waters Associates, Inc. | Ion-pairing chromatography |
Non-Patent Citations (4)
| Title |
|---|
| ANALYTICAL CHEMISTRY, vol. 47, no. 11, septembre 1975, Columbus, Ohio, USA H. SMALL et al. " Novel ion exchange chromatographic method using conductimetric detection" pages 1801-1809 * |
| ANALYTICAL CHEMISTRY, vol. 51, no. 6, mai 1979, Columbus, Ohio, USA F.F. CANTWELL et al. "Mechanism of chromatographic retention of organic ions on a nonionic adsorbent" pages 623-632 * |
| ANALYTICAL CHEMISTRY; vol. 47, no. 8, juillet 1975Columbus, Ohio, USA D.P. WITTMER et al. "Simultaneous analysis of tartrazine and its intermediates by reversed phase liquid chromatography" pages 1422-1423 * |
| LABORPRAXIS "Ionenchromatographie, ein neues Verfahren in der analytischen Chemie" no 3, 1978, VOGEL-VERLAG, W}rzburg pages 2-6 * |
Also Published As
| Publication number | Publication date |
|---|---|
| DE3108924C2 (de) | 1989-07-20 |
| AU6804981A (en) | 1981-09-17 |
| FR2496891B1 (ref) | 1984-06-29 |
| GB2070964B (en) | 1984-01-11 |
| AU546009B2 (en) | 1985-08-08 |
| DE3108924A1 (de) | 1982-02-18 |
| GB2070964A (en) | 1981-09-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Wei et al. | Analysis of carbohydrates in drinks by high-performance liquid chromatography with a dynamically modified amino column and evaporative light scattering detection | |
| Khrolenko et al. | Combination of supported liquid membrane and solid-phase extraction for sample pretreatment of triazine herbicides in juice prior to capillary electrophoresis determination | |
| JP2750002B2 (ja) | バッチ型サプレッサの頻繁な再生を使用するイオンクロマトグラフィ | |
| Werner et al. | A polydimethylsiloxane/deep eutectic solvent sol-gel thin film sorbent and its application to solid-phase microextraction of parabens | |
| Sha et al. | Determination of Sunset Yellow and Tartrazine in Food Samples by Combining Ionic Liquid‐Based Aqueous Two‐Phase System with High Performance Liquid Chromatography | |
| Werner et al. | Development of novel thin‐film solid‐phase microextraction materials based on deep eutectic solvents for preconcentration of trace amounts of parabens in surface waters | |
| Gomez et al. | Solid phase extraction/cyclodextrin-modified micellar electrokinetic chromatography for the analysis of melatonin and related indole compounds in plants | |
| Machida et al. | Enantiomer separation of hydrophobic amino compounds by high-performance liquid chromatography using crown ether dynamically coated chiral stationary phase | |
| Zare et al. | The headspace solid-phase microextraction of polycyclic aromatic hydrocarbons in environmental water samples using silica fiber modified by self assembled gold nanoparticles | |
| Canale et al. | Development of a molecularly imprinted polymer for selective extraction of bisphenol A in water samples | |
| Li et al. | Synthesis and evaluation of a magnetic molecularly imprinted polymer sorbent for determination of trace trichlorfon residue in vegetables by capillary electrophoresis | |
| Paek et al. | Development of a carbon clad core-shell silica for high speed two-dimensional liquid chromatography | |
| Lopes et al. | Determination of hormones in urine by hollow fiber microporous membrane liquid–liquid extraction associated with 96-well plate system and HPLC-FLD detection | |
| Koster et al. | Direct solid-phase microextraction combined with gas and liquid chromatography for the determination of lidocaine in human urine | |
| Buszewski et al. | Linear solvation energy relationships in the determination of phospholipids by supercritical fluid chromatography | |
| Hu et al. | Preparation and evaluation of a pyridine sulfonate betaine-based zwitterionic stationary phase for hydrophilic interaction chromatography | |
| FR2496891A1 (fr) | Methode et appareil d'analyse d'especes ioniques utilisant un milieu de separation chromatographique | |
| Pittler et al. | Enantioseparation of amino acids, α‐hydroxy acids, and dipeptides by ligand‐exchange CEC using silica‐based chiral stationary phases | |
| Zhang et al. | Interface-assisted synthesized covalent organic framework film for efficient extraction of microcystins in aquatic organisms | |
| Mirparizi et al. | Centrifugeless ultrasound‐assisted emulsification microextraction based on salting‐out phenomenon followed by high‐performance liquid chromatography for the simple determination of phthalate esters in aqueous samples | |
| Kaiser et al. | Determination of trace anions in high-nitrate matrices by ion chromatography | |
| Ortiz‐Bolsico et al. | Adsorption of the anionic surfactant sodium dodecyl sulfate on a C18 column under micellar and high submicellar conditions in reversed‐phase liquid chromatography | |
| Vigh et al. | Indirect UV detectionf non-absorbing solutes in reversed-phase high-performance liquid chromatography with the help of UV-active, non-ionic mobile phase constituents | |
| Guijarro‐Díez et al. | Molecularly imprinted SPE and MEKC with in‐capillary sample preconcentration for the determination of digoxin in human urine | |
| Shen et al. | Enantiomeric separation of naphthalene-2, 3-dicarboxaldehyde derivatized dl-3, 4-dihydroxyphenylalanine and optical purity analysis of l-3, 4-dihydroxyphenylalanine drug by cyclodextrin-modified micellar electrokinetic chromatography |