FR2485022B1 - - Google Patents
Info
- Publication number
- FR2485022B1 FR2485022B1 FR8116732A FR8116732A FR2485022B1 FR 2485022 B1 FR2485022 B1 FR 2485022B1 FR 8116732 A FR8116732 A FR 8116732A FR 8116732 A FR8116732 A FR 8116732A FR 2485022 B1 FR2485022 B1 FR 2485022B1
- Authority
- FR
- France
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J33/002—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/041,080 US4269777A (en) | 1979-05-21 | 1979-05-21 | Isotopically labeled vitamin D derivatives and processes for preparing same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2485022A1 FR2485022A1 (fr) | 1981-12-24 |
| FR2485022B1 true FR2485022B1 (en:Method) | 1983-12-09 |
Family
ID=21914616
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8011385A Granted FR2457283A1 (fr) | 1979-05-21 | 1980-05-21 | Derives de la vitamine d marques par un isotope et procede pour les preparer |
| FR8101332A Granted FR2479214A1 (fr) | 1979-05-21 | 1981-01-23 | Nouveaux composes derives de la vitamine d |
| FR8116732A Granted FR2485022A1 (fr) | 1979-05-21 | 1981-09-02 | Nouveaux composes derives de la vitamine d |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8011385A Granted FR2457283A1 (fr) | 1979-05-21 | 1980-05-21 | Derives de la vitamine d marques par un isotope et procede pour les preparer |
| FR8101332A Granted FR2479214A1 (fr) | 1979-05-21 | 1981-01-23 | Nouveaux composes derives de la vitamine d |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4269777A (en:Method) |
| JP (1) | JPS56500538A (en:Method) |
| CA (1) | CA1152488A (en:Method) |
| DE (2) | DE3051094C2 (en:Method) |
| FR (3) | FR2457283A1 (en:Method) |
| GB (4) | GB2052509B (en:Method) |
| IE (3) | IE50424B1 (en:Method) |
| IL (3) | IL69420A (en:Method) |
| WO (1) | WO1980002562A1 (en:Method) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4360470A (en) * | 1980-10-22 | 1982-11-23 | Hoffmann-La Roche Inc. | Process and intermediates for the synthesis of Vitamin D3 metabolites and chenodeoxycholic acid |
| US4411833A (en) * | 1982-05-26 | 1983-10-25 | Wisconsin Alumni Research Foundation | Method for preparing 26,26,26,27,27,27-hexafluoro-1α,25-dihydroxycholesterol |
| NL193245C (nl) * | 1983-05-09 | 1999-04-02 | Wisconsin Alumni Res Found | Aan 1Ó,25-dihydroxyvitamine D2 verwante verbinding en farmaceutisch preparaat met een het calciummetabolisme regulerende werking dat een dergelijke verbinding bevat. |
| US5036061A (en) * | 1983-05-09 | 1991-07-30 | Deluca Hector F | Process for the preparation of 1 alpha,25-dihydroxylated vitamin D2 and related compounds |
| US4585741A (en) * | 1983-08-25 | 1986-04-29 | Clevinger Brian L | Method of assay for vitamin D metabolites |
| US4661294A (en) * | 1985-03-18 | 1987-04-28 | The General Hospital Corporation | Biologically active 1-thio derivatives of vitamin D |
| US4898855A (en) * | 1987-09-14 | 1990-02-06 | Hoffman-La Roche Inc. | Deuterated analogs of 1,25-dihydroxycholecalciferol |
| US5247123A (en) * | 1987-09-14 | 1993-09-21 | Hoffmann-La Roche Inc. | Deuterated analogs of 1,25-dihydroxycholecalciferol |
| JPH02274A (ja) * | 1987-10-14 | 1990-01-05 | Toyo Jozo Co Ltd | 新規な２５−ヒドロキシビタミンｄ↓３誘導体およびその製造法およびそれを用いた定量法 |
| US5202266A (en) * | 1987-10-14 | 1993-04-13 | Asahi Kasei Kogyo Kabushiki Kaisha | 25-hydroxy vitamin D3 derivatives, process for their production, and assay method using the same |
| US5532228A (en) * | 1990-02-06 | 1996-07-02 | Schering Aktiengesellschaft | Side-chain homologous vitamin D derivatives, process for their production, pharmaceutical preparations containing these derivatives and their use as pharmaceutical agents |
| GB9623569D0 (en) * | 1996-11-13 | 1997-01-08 | Immunodiagnostic Systems Ltd | Vitamin D immumoassay systems |
| DE60329500D1 (de) * | 2002-07-12 | 2009-11-12 | Morehouse School Of Medicine | Verfahren zur identifikation von salzempfindlichen personen |
| EP1633703B1 (en) * | 2003-05-30 | 2018-12-26 | PerkinElmer LAS, Inc. | Isotopically labeled chemically stable reagents and process for the synthesis thereof |
| ES2331289B2 (es) * | 2008-06-27 | 2010-06-25 | Universidade De Santiago De Compostela | Compuestos de la vitamina d deuterados. |
| US8642579B2 (en) * | 2009-10-02 | 2014-02-04 | Wisconsin Alumni Research Foundation | 1-desoxy-2-methylene-19-nor-vitamin D analogs and their uses |
| HRP20230747T1 (hr) | 2011-09-08 | 2024-01-05 | Sage Therapeutics, Inc. | Neuroaktivni steroidi, pripravci i njihova uporaba |
| CN105246486B (zh) | 2013-03-13 | 2020-11-03 | 萨奇治疗股份有限公司 | 神经活性甾类化合物 |
| JP6628745B2 (ja) | 2014-06-18 | 2020-01-15 | セージ セラピューティクス， インコーポレイテッド | オキシステロールおよびその使用方法 |
| EP3319610A4 (en) * | 2015-07-06 | 2019-03-06 | Sage Therapeutics, Inc. | OXYSTEROLS AND METHOD OF USE THEREOF |
| ES2865258T3 (es) | 2015-07-06 | 2021-10-15 | Sage Therapeutics Inc | Oxiesteroles y procedimientos de uso de los mismos |
| KR20240166589A (ko) | 2015-07-06 | 2024-11-26 | 세이지 테라퓨틱스, 인크. | 옥시스테롤 및 그의 사용 방법 |
| US10752653B2 (en) | 2016-05-06 | 2020-08-25 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
| EP3919502A1 (en) | 2016-07-07 | 2021-12-08 | Sage Therapeutics, Inc. | 11-substituted 24-hydroxysterols for use in the treatment of nmda related conditions |
| MA46351A (fr) | 2016-09-30 | 2021-06-02 | Sage Therapeutics Inc | Oxystérols substitués en c7 et procédés en tant que modulateurs nmda |
| EP4105223B1 (en) | 2016-10-18 | 2025-04-30 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3833622A (en) * | 1969-03-17 | 1974-09-03 | Upjohn Co | Crystalline 25-hydroxycholecalciferol hydrate and structurally related compounds |
| FR2129011A5 (en:Method) * | 1971-03-11 | 1972-10-27 | Roussel Uclaf | |
| US4119647A (en) * | 1977-04-11 | 1978-10-10 | Hoffmann-La Roche Inc. | 25-Hydroxycholecalciferol-23,24-3 H and process for the preparation thereof |
| US4195027A (en) * | 1978-01-16 | 1980-03-25 | Wisconsin Alumni Research Foundation | Process for preparing 1α-hydroxylated compounds |
-
1979
- 1979-05-21 US US06/041,080 patent/US4269777A/en not_active Expired - Lifetime
-
1980
- 1980-04-29 DE DE3051094A patent/DE3051094C2/de not_active Expired
- 1980-04-29 DE DE803045287T patent/DE3045287T1/de active Granted
- 1980-04-29 WO PCT/US1980/000493 patent/WO1980002562A1/en not_active Ceased
- 1980-04-29 JP JP50127980A patent/JPS56500538A/ja active Pending
- 1980-04-30 CA CA000350960A patent/CA1152488A/en not_active Expired
- 1980-05-12 IL IL69420A patent/IL69420A/xx unknown
- 1980-05-12 IL IL60055A patent/IL60055A/xx unknown
- 1980-05-20 GB GB8016584A patent/GB2052509B/en not_active Expired
- 1980-05-20 GB GB8130231A patent/GB2083043B/en not_active Expired
- 1980-05-20 GB GB8130232A patent/GB2082587B/en not_active Expired
- 1980-05-20 GB GB8123418A patent/GB2077736B/en not_active Expired
- 1980-05-21 IE IE1058/80A patent/IE50424B1/en not_active IP Right Cessation
- 1980-05-21 IE IE2996/83A patent/IE50426B1/en not_active IP Right Cessation
- 1980-05-21 IE IE2995/83A patent/IE50425B1/en not_active IP Right Cessation
- 1980-05-21 FR FR8011385A patent/FR2457283A1/fr active Granted
-
1981
- 1981-01-23 FR FR8101332A patent/FR2479214A1/fr active Granted
- 1981-09-02 FR FR8116732A patent/FR2485022A1/fr active Granted
-
1983
- 1983-08-03 IL IL69420A patent/IL69420A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2485022A1 (fr) | 1981-12-24 |
| IL69420A (en) | 1984-11-30 |
| FR2479214B1 (en:Method) | 1985-04-12 |
| IE50426B1 (en) | 1986-04-16 |
| WO1980002562A1 (en) | 1980-11-27 |
| IE50424B1 (en) | 1986-04-16 |
| GB2082587B (en) | 1983-08-03 |
| GB2052509A (en) | 1981-01-28 |
| JPS56500538A (en:Method) | 1981-04-23 |
| FR2479214A1 (fr) | 1981-10-02 |
| IL69420A0 (en) | 1983-11-30 |
| US4269777A (en) | 1981-05-26 |
| FR2457283B1 (en:Method) | 1983-03-11 |
| CA1152488A (en) | 1983-08-23 |
| DE3051094C2 (en:Method) | 1989-05-18 |
| GB2077736B (en) | 1983-06-29 |
| GB2082587A (en) | 1982-03-10 |
| DE3045287C2 (en:Method) | 1988-11-10 |
| IE50425B1 (en) | 1986-04-16 |
| IE801058L (en) | 1980-11-21 |
| FR2457283A1 (fr) | 1980-12-19 |
| DE3045287T1 (de) | 1982-02-18 |
| GB2052509B (en) | 1983-06-29 |
| IL60055A (en) | 1984-11-30 |
| IL60055A0 (en) | 1980-07-31 |
| GB2083043A (en) | 1982-03-17 |
| GB2077736A (en) | 1981-12-23 |
| GB2083043B (en) | 1983-06-29 |
Similar Documents
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse | ||
| ST | Notification of lapse |