FR2467014A1 - PROCESS FOR THE PRODUCTION OF ACIDS IN THE FORM OF AN EASY SPRAY DRY POWDER AND DRY DISPERSIBLE PRODUCTS OBTAINED BY SAID PROCESS - Google Patents

Abstract

A method of making an acidic dispersible product. Process characterized by a mixture of the acid, in particular lactic acid, with crystallized or powdered anhydrous lactose. Product usable for the manufacture of formula, with low moisture absorption during storage. (CF DRAWING IN BOPI)

Description

The invention relates to a method for the manufacture

  of acids in the form of dry powder easy spray.

  Such powders are known from GB-A-332,597.

  This patent describes a process that relies on the absorption of

  lactic acid with solid carbohydrates, so that these acids are easily

  in which they may be used in

  such as those used in the manufacture of highly digestible artificial formula milk. As a carbohydrate powder dextrose can be used for this purpose, but it is also possible to incorporate lactic acid into milk powder in which lactic acid is naturally present as carbohydrate with a single molecule. water of crystallization, commonly referred to as "lactose

1 aq ".

  Another method is described in NL - A -

  No. 7703510, according to which dispersible, dry, acidic powdery products are obtained which contain at most 30%

  acid. The acid in question is mixed with a friendly product

  hydrolysed product having a coefficient of

  dextrose less than 1. The carbohydrate is supplied in aqueous solution in which the acid is distributed.

  the product in a known manner, for example by spraying

  risking the liquid in a drying tower. This process is applicable to mineral acids, such as phosphoric acid, as well as to organic acids, such as lactic acid or

citric acid.

  The drawbacks of these two known methods, however, lie in the fact that they require a lot of preparation work with very expensive special equipment. On the other hand almost perfect drying is always necessary for

  obtaining a usable product. In the British process

  that, it is actually not required that the carbohydrate

  first be put in solution, so that a large quantity

  liquid should be evaporated and dried. But the mixture of the acid with the carbohydrate in solid form must then be carried out very gradually in order to obtain a homogeneous distribution of the acid through the mass, and

  in addition, subsequent drying, preferably under vacuum, is still

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re and always desirable.

  The present invention aims to avoid the inconveniences

  mentioned above, and to obtain, in a simple manner, a dry, easily sprayable powder. The process of the invention is characterized in that the acid is mixed

  in liquid form with anhydrous lactose in crystalline form

ne or powdery.

  The process according to the invention is particularly suitable

  the manufacture of easily dispersible acid powders

  sands which do not occur in crystalline form at normal temperature, and whose solutions can not be dried by the usual channels, by heating, without

  then produce a decomposition of the acid.

  Thanks to this favorable property relating to its dissociated, non-hygroscopic structure, the powder obtained according to the invention is particularly suitable as an addition to dry products, such as foodstuffs and flavors, medicines, cosmetics and the like, for which

  acid addition is desired, but for which

  common solids, such as citric acid, fumaric acid

  or 8-gluconolactone are unsuitable, and o a dietary addition

  A large number of liquid acids have undesirable effects, including the formation of lumps. The process according to the invention is especially suitable for the transformation of lactic acid

in easily dispersible form.

  It has been found, surprisingly, that the powder obtained by the process which is the subject of the invention absorbed, during store storage, only a very small amount of moisture, whereas lactic acid in dehydrated form is known to be highly hygroscopic. When implementing the

  according to the invention, it has been found that each

simple langer is appropriate.

  The invention is explained below with the aid of a few

examples

Example I

  In a Hobart mixer, quantities of lactose are mixed

  and lactic acid clean to provide 1 kilogram of product.

  For each ratio of proportions of acid-mixture

  lactose used in this test, experiments were carried out,

3, 2467014.-

  on the one hand with anhydrous lactose and on the other hand with

  normal pharmaceutical grade lactose.

  Table 1 indicates the composition of the various mixtures using the percentage of lactic acid in the product obtained, as well as a judgment on the quality of dispersion of the product. The lactic acid used contained 20%

  of water and was sprayed on the lactose.

  Taleau 1 Number% lactic acid Type of lactose Product quality 1 To 10 anhydrous dispersible

2 to 15

3 to 20

1 B 10 pasty pharmaceutical

2 B 15

3 B 20

  As shown in Table 1, all mixtures of lactic acid with anhydrous lactose gave very dispersible products, unlike mixtures of lactic acid with normal pharmaceutical lactose which gave the products more or less pasty. A comparison of the dissociated structure by simple visual observation was in all cases in favor

  products based on anhydrous lactose.

  The two products comprising 10% lactic acid were further subjected to the following tests: 1. Fluidity, defined as the maximum angle with the horizontal line for which the powder can spread on a

round surface.

  2. Flow velocity in a granulate flowmeter

  3. Percentage of powder output from a rotating cylinder

  tif with an opening of a given diameter.

  The results of these tests are reproduced in the

table 2.

Table 2

  Product Fluidity Flow rate% output 50 g% lactic acid with 44.20 3.5 g 78%

lactose anhy-

dre

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% of lac-acid

  With the product with 15% lactic acid and lactose anhydrous moisture absorption during storage was determined in the case of different relative humidities (RV). The results are given in the form of a graph in which the abscissas X represent the time in hours and the

  Y-ordinates represent the percentage of moisture absorbed.

  Although lactic acid, in the dry state is strongly hygros-

  the product with 15% lactic acid and lactose anhydrous absorbs relatively less moisture

  its dissociated texture remains preserved.

Example

  In a domestic mixer apparatus, amounts of anhydrous lactose and lactic acid at 80% were mixed to give 300 grams of product with a lactic acid content of 10%. The product obtained had a dry appearance and was

easily dispersible.

  Comparative Example I Operating according to Example I, the Hobart blender was blended with dextrose of the commercial product.

  "Cerelose 02001" and lactic acid.

  The products obtained were very pasty and almost

agglomerates.

  Comparative Example II In the same manner as in Example I, lactic acid was mixed with anhydrous dextrose of the commercial product "Cerelose 02402". There, also we obtained pasty products,

non-dispersible.

Example III

  In a 2 liter container with a Heidolph stirrer

  and a transparent lid, were mixed lactose anhy-

  and 96% pure acetic acid. We got a product

  of dissociated structure containing 15% by weight of acetic acid.

2467014.

Claims (5)

-R E V E N D I C AT IO N S-   A process for producing acid in the form of a readily dispersible dry powder, characterized by mixing the acid with anhydrous lactose in crystalline or powder form. 2. Process according to Claim 1, characterized in that a non-crystallizable acid is used for mixing with anhydrous lactose at normal temperature and not drying out by warming up.   3. Process according to any one of the claims   1 and 2, characterized in that lactic acid is mixed with anhydrous lactose.   4. Dry dispersible product, conforming to that obtained   by applying the method according to any one of the   1 to 3, characterized by a mixture of acid as   lactic acid, with anhydrous lactose.   5. Product according to claim 4, characterized   what it contains, in addition, other dry products.