FR2455610A1 - NOVEL 5A-REDUCTASE INHIBITOR STEROIDS, ESPECIALLY USEFUL FOR THE TREATMENT OF ACNE AND THEIR PREPARATION PROCESS - Google Patents

NOVEL 5A-REDUCTASE INHIBITOR STEROIDS, ESPECIALLY USEFUL FOR THE TREATMENT OF ACNE AND THEIR PREPARATION PROCESS

Info

Publication number
FR2455610A1
FR2455610A1 FR8009848A FR8009848A FR2455610A1 FR 2455610 A1 FR2455610 A1 FR 2455610A1 FR 8009848 A FR8009848 A FR 8009848A FR 8009848 A FR8009848 A FR 8009848A FR 2455610 A1 FR2455610 A1 FR 2455610A1
Authority
FR
France
Prior art keywords
acne
treatment
steroids
novel
preparation process
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8009848A
Other languages
French (fr)
Other versions
FR2455610B1 (en
Inventor
Thomas R Blohm
Brian W Metcalf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richardson Vicks Inc
Original Assignee
Richardson Merrell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc
Publication of FR2455610A1 publication Critical patent/FR2455610A1/en
Application granted granted Critical
Publication of FR2455610B1 publication Critical patent/FR2455610B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

NOUVEAUX STEROIDES, LEUR PREPARATION ET LEURS UTILISATIONS THERAPEUTIQUES. CES STEROIDES REPONDENT A LA FORMULE: (CF DESSIN DANS BOPI) DANS LAQUELLE R REPRESENTE: (CF DESSIN DANS BOPI) CES STEROIDES PEUVENT ETRE UTILISES AVANTAGEUSEMENT EN THERAPEUTIQUE POUR LE TRAITEMENT DE L'ACNE, DES PEAUX GRASSES ET DE L'HYPERTROPHIE DE LA PROSTATE.NEW STEROIDS, THEIR PREPARATION AND THEIR THERAPEUTIC USES. THESE STEROIDS COMPLY WITH THE FORMULA: (CF DRAWING IN BOPI) IN WHICH R REPRESENTS: (CF DRAWING IN BOPI) THESE STEROIDS CAN BE USED ADVANTAGEALLY IN THERAPEUTICS FOR THE TREATMENT OF ACNE, OILY SKIN AND HYPERTROPHY OF THE PROSTATE.

FR8009848A 1979-05-02 1980-04-30 NOVEL 5A-REDUCTASE INHIBITOR STEROIDS, ESPECIALLY USEFUL FOR THE TREATMENT OF ACNE AND THEIR PREPARATION PROCESS Granted FR2455610A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3535779A 1979-05-02 1979-05-02
US6974179A 1979-08-27 1979-08-27

Publications (2)

Publication Number Publication Date
FR2455610A1 true FR2455610A1 (en) 1980-11-28
FR2455610B1 FR2455610B1 (en) 1982-04-30

Family

ID=26712031

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8009848A Granted FR2455610A1 (en) 1979-05-02 1980-04-30 NOVEL 5A-REDUCTASE INHIBITOR STEROIDS, ESPECIALLY USEFUL FOR THE TREATMENT OF ACNE AND THEIR PREPARATION PROCESS

Country Status (16)

Country Link
AT (1) AT390794B (en)
AU (1) AU532558B2 (en)
CA (1) CA1154008A (en)
CH (1) CH643863A5 (en)
DE (1) DE3017015A1 (en)
DK (1) DK166501B1 (en)
ES (1) ES8105012A1 (en)
FR (1) FR2455610A1 (en)
GB (1) GB2048888B (en)
IE (1) IE49704B1 (en)
IL (1) IL59934A (en)
IT (1) IT1188932B (en)
NL (1) NL191387C (en)
NO (1) NO154884C (en)
NZ (1) NZ193527A (en)
SE (1) SE448097B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8503940D0 (en) * 1985-02-15 1985-03-20 Erba Farmitalia 4-substituted androstendione derivatives
NZ239142A (en) * 1990-08-01 1994-05-26 Merrell Dow Pharma 4-amino-delta-4-steroids; preparatory processes and pharmaceutical compositions
US5143909A (en) * 1991-03-19 1992-09-01 Merrell Dow Pharmaceuticals Inc. Aminosteroids in a method for inhibiting c17-20 lyase
AU642757B2 (en) * 1990-08-01 1993-10-28 Merrell Dow Pharmaceuticals Inc. 4-amino-delta4, 6-steroids and their use as 5alpha-reductase inhibitors
EP0794456B1 (en) 1996-03-07 2003-01-29 Agfa-Gevaert Method of reproducing an electronically stored medical image on a light-sensitive photographic material

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3917829A (en) * 1971-11-08 1975-11-04 Research Corp Novel methods of inhibiting the activity of testosterone 5{60 -reductase
US4088760A (en) * 1976-06-23 1978-05-09 Richardson-Merrell Inc. Testosterone 5α-reductase inhibitors

Also Published As

Publication number Publication date
ES491010A0 (en) 1981-05-16
IE800806L (en) 1980-11-02
ES8105012A1 (en) 1981-05-16
FR2455610B1 (en) 1982-04-30
DE3017015A1 (en) 1980-11-20
NL8002529A (en) 1980-11-04
CA1154008A (en) 1983-09-20
GB2048888A (en) 1980-12-17
IT1188932B (en) 1988-01-28
IE49704B1 (en) 1985-11-27
GB2048888B (en) 1983-05-25
AT390794B (en) 1990-06-25
DK166501B1 (en) 1993-06-01
AU5774780A (en) 1980-11-06
NZ193527A (en) 1984-10-19
IL59934A0 (en) 1980-06-30
SE448097B (en) 1987-01-19
CH643863A5 (en) 1984-06-29
DE3017015C2 (en) 1989-04-20
IL59934A (en) 1983-06-15
IT8048559A1 (en) 1981-10-30
NL191387C (en) 1995-07-03
ATA232880A (en) 1989-12-15
IT8048559A0 (en) 1980-04-30
SE8003242L (en) 1980-11-03
DK194180A (en) 1980-11-03
NO154884C (en) 1987-01-07
NO801254L (en) 1980-11-03
NO154884B (en) 1986-09-29
AU532558B2 (en) 1983-10-06
NL191387B (en) 1995-02-01

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