FR2453640A1 - Compositions therapeutiques a usage oral et a liberation programmee du methanesulfonate de dihydroergotamine - Google Patents
Compositions therapeutiques a usage oral et a liberation programmee du methanesulfonate de dihydroergotamineInfo
- Publication number
- FR2453640A1 FR2453640A1 FR7909268A FR7909268A FR2453640A1 FR 2453640 A1 FR2453640 A1 FR 2453640A1 FR 7909268 A FR7909268 A FR 7909268A FR 7909268 A FR7909268 A FR 7909268A FR 2453640 A1 FR2453640 A1 FR 2453640A1
- Authority
- FR
- France
- Prior art keywords
- anionic
- plasticiser
- cationic
- methacrylic acid
- polymers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920000642 polymer Polymers 0.000 title abstract 4
- 125000000129 anionic group Chemical group 0.000 title abstract 3
- AFVFQIVMOAPDHO-UHFFFAOYSA-M Methanesulfonate Chemical compound CS([O-])(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-M 0.000 title abstract 2
- 239000004014 plasticizer Substances 0.000 title abstract 2
- 238000013270 controlled release Methods 0.000 title 1
- 229960004943 ergotamine Drugs 0.000 title 1
- 239000008187 granular material Substances 0.000 title 1
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 abstract 3
- 208000019695 Migraine disease Diseases 0.000 abstract 2
- 125000002091 cationic group Chemical group 0.000 abstract 2
- 239000011248 coating agent Substances 0.000 abstract 2
- 238000000576 coating method Methods 0.000 abstract 2
- FLKPEMZONWLCSK-UHFFFAOYSA-N diethyl phthalate Chemical compound CCOC(=O)C1=CC=CC=C1C(=O)OCC FLKPEMZONWLCSK-UHFFFAOYSA-N 0.000 abstract 2
- 206010010774 Constipation Diseases 0.000 abstract 1
- 229920002261 Corn starch Polymers 0.000 abstract 1
- 206010013935 Dysmenorrhoea Diseases 0.000 abstract 1
- 235000019759 Maize starch Nutrition 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract 1
- 229930006000 Sucrose Natural products 0.000 abstract 1
- 201000002816 chronic venous insufficiency Diseases 0.000 abstract 1
- HESHRHUZIWVEAJ-JGRZULCMSA-N dihydroergotamine Chemical compound C([C@H]1C(=O)N2CCC[C@H]2[C@]2(O)O[C@@](C(N21)=O)(C)NC(=O)[C@H]1CN([C@H]2[C@@H](C3=CC=CC4=NC=C([C]34)C2)C1)C)C1=CC=CC=C1 HESHRHUZIWVEAJ-JGRZULCMSA-N 0.000 abstract 1
- 229960004704 dihydroergotamine Drugs 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 206010027599 migraine Diseases 0.000 abstract 1
- 230000002746 orthostatic effect Effects 0.000 abstract 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 abstract 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 abstract 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 abstract 1
- 239000005720 sucrose Substances 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
- 239000000454 talc Substances 0.000 abstract 1
- 229910052623 talc Inorganic materials 0.000 abstract 1
- 201000002282 venous insufficiency Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7909268A FR2453640A1 (fr) | 1979-04-12 | 1979-04-12 | Compositions therapeutiques a usage oral et a liberation programmee du methanesulfonate de dihydroergotamine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7909268A FR2453640A1 (fr) | 1979-04-12 | 1979-04-12 | Compositions therapeutiques a usage oral et a liberation programmee du methanesulfonate de dihydroergotamine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2453640A1 true FR2453640A1 (fr) | 1980-11-07 |
| FR2453640B1 FR2453640B1 (Direct) | 1982-05-21 |
Family
ID=9224258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7909268A Granted FR2453640A1 (fr) | 1979-04-12 | 1979-04-12 | Compositions therapeutiques a usage oral et a liberation programmee du methanesulfonate de dihydroergotamine |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2453640A1 (Direct) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2477015A1 (fr) * | 1980-03-03 | 1981-09-04 | Fabre Sa Pierre | Composition pharmaceutique a base d'un alcaloide de l'ergot de seigle, a activite regulatrice sur le tonus vasculaire |
| FR2539989A1 (fr) * | 1983-01-28 | 1984-08-03 | Sanofi Sa | Medicament a liberation programmee associant l'acide acetylsalicylique a la dihydroergotamine |
| US4726966A (en) * | 1985-11-27 | 1988-02-23 | Showa Shinyaku Co., Ltd. | Preparation of coated granular ibuprofen microsphere |
| WO1995008323A1 (de) * | 1993-09-23 | 1995-03-30 | Dr. Falk Pharma Gmbh | Budesonid-pellets mit kontrolliertem freigabeprofil und verfahren zu ihrer herstellung |
-
1979
- 1979-04-12 FR FR7909268A patent/FR2453640A1/fr active Granted
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2477015A1 (fr) * | 1980-03-03 | 1981-09-04 | Fabre Sa Pierre | Composition pharmaceutique a base d'un alcaloide de l'ergot de seigle, a activite regulatrice sur le tonus vasculaire |
| EP0036350A1 (fr) * | 1980-03-03 | 1981-09-23 | Pierre Fabre Medicament | Composition pharmaceutique à activité régulatrice sur le tonus vasculaire |
| FR2539989A1 (fr) * | 1983-01-28 | 1984-08-03 | Sanofi Sa | Medicament a liberation programmee associant l'acide acetylsalicylique a la dihydroergotamine |
| EP0117164A1 (fr) * | 1983-01-28 | 1984-08-29 | Elf Sanofi | Médicament à libération programmée associant l'acide acétylsalicylique à la dihydroergotamine |
| US4726966A (en) * | 1985-11-27 | 1988-02-23 | Showa Shinyaku Co., Ltd. | Preparation of coated granular ibuprofen microsphere |
| WO1995008323A1 (de) * | 1993-09-23 | 1995-03-30 | Dr. Falk Pharma Gmbh | Budesonid-pellets mit kontrolliertem freigabeprofil und verfahren zu ihrer herstellung |
| US5932249A (en) * | 1993-09-23 | 1999-08-03 | Dr. Falk Pharma Gmbh | Budesonide pellets with a controlled released pattern and process for producing the same |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2453640B1 (Direct) | 1982-05-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO156454C (no) | Fremgangsmaate for aa anbringe et hydrofilt belegg paa en polymeroverflate, samt medisinsk artikkel med et saaledes fremstilt belegg | |
| UA27043C2 (uk) | Мікросферичhі частиhки для пареhтеральhої іh'єкції фармацевтичhо активhої речовиhи при її коhтрольоваhому виділеhhі в оргаhізмі після іh'єкції, спосіб їх одержаhhя та суспеhзія hа осhові даhих мікросфер | |
| EP0259219A3 (en) | Controlled release tablet | |
| NO831409L (no) | Fremgangsmaate for fremstilling av et hydrofilt belegg | |
| ES2094431T3 (es) | Microgranulos de pancreatina con un revestimiento resistente a los jugos gastricos. | |
| HU9300083D0 (en) | Stabilized acryl-polymer coated preparatives with controlled releasing of active agent | |
| NO992994D0 (no) | Legemidler mot hoste avlevert av ionebytterharpikser | |
| CA2225096A1 (en) | Method of applying drug-release coatings | |
| ES8400029A1 (es) | Procedimiento para la preparacion de una suspension hidroalcoholica. | |
| ES9400003A1 (es) | Procedimiento para la preparacion de substratos con capacidad de absorcion a base de dispersiones de plastico. | |
| ATE150963T1 (de) | Kugelförmige granula mit kern sowie deren herstellung | |
| IT1241417B (it) | Composizioni terapeutiche a rilascio controllato di farmaci supportatisu polimeri reticolati e rivestiti con film polimerici,e loro processodi preparazione | |
| EP0171528A3 (en) | Controlled release pharmaceutical preparations | |
| FR2453640A1 (fr) | Compositions therapeutiques a usage oral et a liberation programmee du methanesulfonate de dihydroergotamine | |
| FR2453642A1 (fr) | Compositions therapeutiques a usage oral et a liberation programmee du methanesulfonate de dihydroergotoxine | |
| EP0371258A3 (en) | Surface-hydrated porous polyacrylonitrile substrates, such as beads derivatives thereof, process for their preparation, and methods for their use | |
| FR2073007A5 (en) | Immobielised active enzyme products | |
| NO160133C (no) | Analogifremgangsmaate ved fremstilling av terapeutisk aktive 2-amino-3-(halobenzoyl)-methylfenyleddiksyrer, estere og salter derav. | |
| IL115450A (en) | Process for coating powders with polymers | |
| GB1504101A (en) | Non-thrombogenic catheter | |
| JPS56158712A (en) | Oral microcapsule of active carbon | |
| AU6285786A (en) | Soluble acrylic copolymer containing carboxyl groups, its production process and coating agent on the basis of this acrylic copolymer | |
| PL237148A1 (en) | Polymerous watery dispersion,method of obtaining polymerous watery dispersion,coating composition and method of applying a coat | |
| FR2422419A1 (fr) | Dispositif perfectionne pour le fartage des skis | |
| JPS5911183A (ja) | 酵素固定化物およびその製造方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TP | Transmission of property | ||
| CA | Change of address | ||
| CD | Change of name or company name | ||
| ST | Notification of lapse |