FR2453640A1 - Compositions therapeutiques a usage oral et a liberation programmee du methanesulfonate de dihydroergotamine - Google Patents

Compositions therapeutiques a usage oral et a liberation programmee du methanesulfonate de dihydroergotamine

Info

Publication number
FR2453640A1
FR2453640A1 FR7909268A FR7909268A FR2453640A1 FR 2453640 A1 FR2453640 A1 FR 2453640A1 FR 7909268 A FR7909268 A FR 7909268A FR 7909268 A FR7909268 A FR 7909268A FR 2453640 A1 FR2453640 A1 FR 2453640A1
Authority
FR
France
Prior art keywords
anionic
plasticiser
cationic
methacrylic acid
polymers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7909268A
Other languages
English (en)
Other versions
FR2453640B1 (fr
Inventor
Hubert Armand
Roland Segonds
Pierre Lotteau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Labaz SA
Original Assignee
Labaz SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labaz SA filed Critical Labaz SA
Priority to FR7909268A priority Critical patent/FR2453640A1/fr
Publication of FR2453640A1 publication Critical patent/FR2453640A1/fr
Application granted granted Critical
Publication of FR2453640B1 publication Critical patent/FR2453640B1/fr
Granted legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/48Ergoline derivatives, e.g. lysergic acid, ergotamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

Abstract

L'INVENTION SE RAPPORTE A DES MICROGRANULES A LIBERATION PROGRAMMEE DANS LE TEMPS DE LEUR PRINCIPE ACTIF AINSI QU'AUX COMPOSITIONS THERAPEUTIQUES LES CONTENANT. LES MICROGRANULES SELON L'INVENTION SONT CONSTITUES: -D'UN SUPPORT DE MATIERE INACTIVE; -D'UN DEPOT DE PRINCIPE ACTIF REPRESENTE PAR LE METHANESULFONATE DE DIHYDROERGOTAMINE, CE DEPOT ETANT FIXE SUR LE SUPPORT; -D'UN FILM D'ENROBAGE FIXE SUR LE PRINCIPE ACTIF ET CONSTITUE D'UN MELANGE DE DEUX POLYMERES DE L'ACIDE METHACRYLIQUE A SAVOIR UN POLYMERE ANIONIQUE ET UN POLYMERE CATIONIQUE ET D'UN PLASTIFIANT. LES COMPOSITIONS THERAPEUTIQUES A USAGE ORAL SELON L'INVENTION CONTIENNENT DES MICROGRANULES A LIBERATION PROGRAMMEE COMME DECRITS CI-DESSUS ET EVENTUELLEMENT DES MICROGRANULES NEUTRES ETOU A LIBERATION IMMEDIATE.
FR7909268A 1979-04-12 1979-04-12 Compositions therapeutiques a usage oral et a liberation programmee du methanesulfonate de dihydroergotamine Granted FR2453640A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7909268A FR2453640A1 (fr) 1979-04-12 1979-04-12 Compositions therapeutiques a usage oral et a liberation programmee du methanesulfonate de dihydroergotamine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7909268A FR2453640A1 (fr) 1979-04-12 1979-04-12 Compositions therapeutiques a usage oral et a liberation programmee du methanesulfonate de dihydroergotamine

Publications (2)

Publication Number Publication Date
FR2453640A1 true FR2453640A1 (fr) 1980-11-07
FR2453640B1 FR2453640B1 (fr) 1982-05-21

Family

ID=9224258

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7909268A Granted FR2453640A1 (fr) 1979-04-12 1979-04-12 Compositions therapeutiques a usage oral et a liberation programmee du methanesulfonate de dihydroergotamine

Country Status (1)

Country Link
FR (1) FR2453640A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2477015A1 (fr) * 1980-03-03 1981-09-04 Fabre Sa Pierre Composition pharmaceutique a base d'un alcaloide de l'ergot de seigle, a activite regulatrice sur le tonus vasculaire
FR2539989A1 (fr) * 1983-01-28 1984-08-03 Sanofi Sa Medicament a liberation programmee associant l'acide acetylsalicylique a la dihydroergotamine
US4726966A (en) * 1985-11-27 1988-02-23 Showa Shinyaku Co., Ltd. Preparation of coated granular ibuprofen microsphere
WO1995008323A1 (fr) * 1993-09-23 1995-03-30 Dr. Falk Pharma Gmbh Pellets de budesonide a liberation controlee et leur procede de preparation

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2477015A1 (fr) * 1980-03-03 1981-09-04 Fabre Sa Pierre Composition pharmaceutique a base d'un alcaloide de l'ergot de seigle, a activite regulatrice sur le tonus vasculaire
EP0036350A1 (fr) * 1980-03-03 1981-09-23 Pierre Fabre Medicament Composition pharmaceutique à activité régulatrice sur le tonus vasculaire
FR2539989A1 (fr) * 1983-01-28 1984-08-03 Sanofi Sa Medicament a liberation programmee associant l'acide acetylsalicylique a la dihydroergotamine
EP0117164A1 (fr) * 1983-01-28 1984-08-29 Elf Sanofi Médicament à libération programmée associant l'acide acétylsalicylique à la dihydroergotamine
US4726966A (en) * 1985-11-27 1988-02-23 Showa Shinyaku Co., Ltd. Preparation of coated granular ibuprofen microsphere
WO1995008323A1 (fr) * 1993-09-23 1995-03-30 Dr. Falk Pharma Gmbh Pellets de budesonide a liberation controlee et leur procede de preparation
US5932249A (en) * 1993-09-23 1999-08-03 Dr. Falk Pharma Gmbh Budesonide pellets with a controlled released pattern and process for producing the same

Also Published As

Publication number Publication date
FR2453640B1 (fr) 1982-05-21

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Legal Events

Date Code Title Description
TP Transmission of property
CA Change of address
CD Change of name or company name
ST Notification of lapse