FR2451365A1 - Derive de l'isoindoline, procede pour sa preparation et compositions therapeutiques qui le contiennent en tant que principe actif - Google Patents

Derive de l'isoindoline, procede pour sa preparation et compositions therapeutiques qui le contiennent en tant que principe actif

Info

Publication number
FR2451365A1
FR2451365A1 FR8005504A FR8005504A FR2451365A1 FR 2451365 A1 FR2451365 A1 FR 2451365A1 FR 8005504 A FR8005504 A FR 8005504A FR 8005504 A FR8005504 A FR 8005504A FR 2451365 A1 FR2451365 A1 FR 2451365A1
Authority
FR
France
Prior art keywords
methyl
isoindoline
preparation
active ingredient
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8005504A
Other languages
English (en)
Other versions
FR2451365B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Farmatis SpA
Original Assignee
Farmatis SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmatis SpA filed Critical Farmatis SpA
Publication of FR2451365A1 publication Critical patent/FR2451365A1/fr
Application granted granted Critical
Publication of FR2451365B1 publication Critical patent/FR2451365B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

LE BREVET CONCERNE UN NOUVEAU COMPOSE QUI EST LA 1-METHYL-2-(3-SULFAMYL-4-CHLOROBENZAMIDO)-ISOINDOLINE DE FORMULE: (CF DESSIN DANS BOPI) CE COMPOSE, QUI EST DOTE D'UNE ACTIVITE DIURETIQUE, SALURETIQUE ET HYPOTENSIVE, EST PREPARE: A.EN FAISANT REAGIR UN A-METHYL-A,A-DIBROMO-O.XYLENE AVEC UN CARBAZATE DE BUTYLE TERT.; B.EN DECOMPOSANT LA 1-METHYL-N-(BUTYL TERT.-OXYCARBONYLAMINO)-ISOINDOLINE AINSI OBTENUE EN LE COMPOSE AMINE CORRESPONDANT; C.EN FAISANT REAGIR LE CHLORHYDRATE DE 1-METHYL-2-AMINO-ISOINDOLINE AVEC UN HALOGENURE D'ACIDE 4-CHLORO-SULFAMIDOBENZOIQUE.
FR8005504A 1979-03-15 1980-03-12 Derive de l'isoindoline, procede pour sa preparation et compositions therapeutiques qui le contiennent en tant que principe actif Granted FR2451365A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20991/79A IT1113879B (it) 1979-03-15 1979-03-15 Derivato isoindolinico,processo per la sua preparazione e composizioni terapeutiche che lo comprendono come principio attivo

Publications (2)

Publication Number Publication Date
FR2451365A1 true FR2451365A1 (fr) 1980-10-10
FR2451365B1 FR2451365B1 (fr) 1983-03-11

Family

ID=11175061

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8005504A Granted FR2451365A1 (fr) 1979-03-15 1980-03-12 Derive de l'isoindoline, procede pour sa preparation et compositions therapeutiques qui le contiennent en tant que principe actif

Country Status (17)

Country Link
US (1) US4338331A (fr)
JP (1) JPS55127369A (fr)
AT (1) AT374179B (fr)
AU (1) AU533082B2 (fr)
BE (1) BE882239A (fr)
CA (1) CA1117130A (fr)
CS (1) CS210641B2 (fr)
DE (1) DE3009932C2 (fr)
ES (1) ES8102554A1 (fr)
FR (1) FR2451365A1 (fr)
GB (1) GB2047241B (fr)
GR (1) GR66632B (fr)
IT (1) IT1113879B (fr)
NL (1) NL8001545A (fr)
SE (1) SE8002001L (fr)
YU (1) YU70080A (fr)
ZA (1) ZA801426B (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2003311A1 (fr) * 1968-03-06 1969-11-07 Science Union & Cie
GB1193289A (en) * 1965-07-14 1970-05-28 Science Union & Cie New Isoindolino-Sulphonylurea Derivatives and Process for Preparing them
FR2265365A1 (fr) * 1974-03-29 1975-10-24 Siegfried Ag

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL129208C (fr) * 1965-07-14
FR1557903A (fr) * 1968-01-09 1969-02-21
US4178293A (en) * 1978-04-14 1979-12-11 Zoecon Corporation Isoindolinyl derivatives

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1193289A (en) * 1965-07-14 1970-05-28 Science Union & Cie New Isoindolino-Sulphonylurea Derivatives and Process for Preparing them
FR2003311A1 (fr) * 1968-03-06 1969-11-07 Science Union & Cie
FR2265365A1 (fr) * 1974-03-29 1975-10-24 Siegfried Ag

Also Published As

Publication number Publication date
DE3009932A1 (de) 1980-09-25
YU70080A (en) 1983-01-21
GB2047241B (en) 1983-01-26
BE882239A (fr) 1980-07-01
SE8002001L (sv) 1980-09-16
AU533082B2 (en) 1983-10-27
ES489539A0 (es) 1981-02-16
ES8102554A1 (es) 1981-02-16
IT7920991A0 (it) 1979-03-15
AT374179B (de) 1984-03-26
ATA139780A (de) 1983-08-15
FR2451365B1 (fr) 1983-03-11
ZA801426B (en) 1980-12-31
IT1113879B (it) 1986-01-27
DE3009932C2 (de) 1983-04-07
JPS55127369A (en) 1980-10-02
GB2047241A (en) 1980-11-26
NL8001545A (nl) 1980-09-17
GR66632B (fr) 1981-04-03
AU5640780A (en) 1980-09-18
CS210641B2 (en) 1982-01-29
CA1117130A (fr) 1982-01-26
US4338331A (en) 1982-07-06

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Legal Events

Date Code Title Description
ST Notification of lapse