FR2441616B1 - Nouvel imidazole, procede pour sa preparation et son application therapeutique - Google Patents

Nouvel imidazole, procede pour sa preparation et son application therapeutique

Info

Publication number
FR2441616B1
FR2441616B1 FR7928099A FR7928099A FR2441616B1 FR 2441616 B1 FR2441616 B1 FR 2441616B1 FR 7928099 A FR7928099 A FR 7928099A FR 7928099 A FR7928099 A FR 7928099A FR 2441616 B1 FR2441616 B1 FR 2441616B1
Authority
FR
France
Prior art keywords
preparation
therapeutic application
novel imidazole
imidazole
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7928099A
Other languages
English (en)
Other versions
FR2441616A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP13932578A external-priority patent/JPS5566562A/ja
Priority claimed from JP14281378A external-priority patent/JPS5569567A/ja
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of FR2441616A1 publication Critical patent/FR2441616A1/fr
Application granted granted Critical
Publication of FR2441616B1 publication Critical patent/FR2441616B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR7928099A 1978-11-14 1979-11-14 Nouvel imidazole, procede pour sa preparation et son application therapeutique Expired FR2441616B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP13932578A JPS5566562A (en) 1978-11-14 1978-11-14 Novel imidazole derivative and antidepressant containing the same
JP14281378A JPS5569567A (en) 1978-11-21 1978-11-21 Novel imidazole compound, and antidepressant containing the same

Publications (2)

Publication Number Publication Date
FR2441616A1 FR2441616A1 (fr) 1980-06-13
FR2441616B1 true FR2441616B1 (fr) 1986-05-09

Family

ID=26472162

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7928099A Expired FR2441616B1 (fr) 1978-11-14 1979-11-14 Nouvel imidazole, procede pour sa preparation et son application therapeutique

Country Status (9)

Country Link
US (4) US4301169A (fr)
CA (1) CA1126272A (fr)
CH (1) CH642635A5 (fr)
DE (1) DE2946020A1 (fr)
FR (1) FR2441616B1 (fr)
GB (1) GB2044754B (fr)
IT (1) IT1127223B (fr)
NL (1) NL7908331A (fr)
SE (1) SE447653B (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE447653B (sv) * 1978-11-14 1986-12-01 Eisai Co Ltd Imidazolderivat samt farmaceutisk komposition innehallande sadant derivat
US4353905A (en) * 1981-09-17 1982-10-12 Warner-Lambert Company Substituted 4,5-dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones and 6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones
US5138069A (en) * 1986-07-11 1992-08-11 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking imidazoles
CA1334092C (fr) * 1986-07-11 1995-01-24 David John Carini Imidazoles bloquant les recepteurs de l'angiotensine ii
US4851526A (en) * 1987-09-04 1989-07-25 Schering A.G. 1-(4-Substituted phenyl)-1H-imidazoles compounds
US5210079A (en) * 1988-01-07 1993-05-11 E. I. Du Pont De Nemours And Company Treatment of chronic renal failure with imidazole angiotensin-II receptor antagonists
DE122010000024I1 (de) * 1990-02-19 2010-07-08 Novartis Ag Acylverbindungen
KR910021381A (ko) * 1990-02-20 1991-12-20 모리 히데오 4-3급 부틸이미다졸 유도체, 및 이의 제조방법 및 용도
US5140037A (en) * 1990-03-20 1992-08-18 E. I. Du Pont De Nemours And Company Treatment of central nervous system disorders with imidazole angiotensin-ii receptor antagonists
US5137906A (en) * 1990-03-20 1992-08-11 E. I. Du Pont De Nemours And Company Treatment of central nervous system disorders with benzimidazole angiotensin-II receptor antagonists
US5173494A (en) * 1990-03-20 1992-12-22 E. I. Du Pont De Nemours And Company Specific inhibition of angiotensin-II binding to angiotensin-II receptor subtype-2
US5179113A (en) * 1990-03-20 1993-01-12 E. I. Du Pont De Nemours And Company Treatment of central nervous disorders with imidazole compounds
US5155126A (en) * 1990-03-20 1992-10-13 E. I. Du Pont De Nemours And Company Treatment of central nervous system disorders with pyrazole, pyrrole and triazole angiotensin-II receptor antagonists
CA2036148A1 (fr) * 1990-06-29 1991-12-30 Hiroki Tomioka Derive de 1-phenylimidazole ainsi que sa production et son utilisation
US5187271A (en) * 1991-02-28 1993-02-16 G. D. Searle & Co. N-substituted (α-imidazolyl-toluyl) pyrrole compounds for treatment of circulatory disorders
US6008368A (en) * 1993-04-28 1999-12-28 G. D. Searle & Co. Pharmaceutical compositions for treatment of circulatory disorders using N-substituted (α-imidazolyl-toluyl) pyrrole aniotensin II antagonists
US5451597A (en) * 1993-05-27 1995-09-19 G.D. Searle & Co. Treatment of circulatory disorders using n-substituted (α-imidazolyl-toluyl) pyrrole angiotensin II antagonists
AU2352295A (en) * 1994-04-27 1995-11-16 Nippon Soda Co., Ltd. Imidazole derivative and process for producing the same
AU753360B2 (en) 1998-07-31 2002-10-17 Nippon Soda Co., Ltd. Phenylazole compounds, process for producing the same and drugs for hyperlipemia
AUPQ319899A0 (en) * 1999-10-01 1999-10-28 Fujisawa Pharmaceutical Co., Ltd. Amide compounds
US6627647B1 (en) * 2000-03-23 2003-09-30 Boehringer Ingelheim Pharmaceuticals, Inc. Substituted 1-(4-aminophenyl)imidazoles and their use as anti-inflammatory agents
JP4377881B2 (ja) * 2003-08-01 2009-12-02 日本曹達株式会社 フェニルアゾール化合物、製造法および抗酸化薬
PL1858877T3 (pl) * 2005-01-14 2014-08-29 Gilead Connecticut Inc 1,3 podstawione diarylem moczniki jako modulatory aktywności kinazy
CA2594449A1 (fr) * 2005-01-14 2006-07-20 Cgi Pharmaceuticals, Inc. Urees a substitution 1,3-diaryle, modulateurs de l'activite de kinases
US7777040B2 (en) * 2005-05-03 2010-08-17 Cgi Pharmaceuticals, Inc. Certain substituted ureas, as modulators of kinase activity
WO2008039794A1 (fr) * 2006-09-25 2008-04-03 Arete Therapeutics, Inc. Inhibiteurs d'époxyde hydrolase soluble
EP2081898A2 (fr) * 2006-10-20 2009-07-29 Arete Therapeutics, INC. Composes adamantyluree comme inhibiteurs d'epoxyde hydrolase soluble
EP2890415B1 (fr) 2012-08-28 2020-09-23 3M Innovative Properties Company Compositions de gluconate de chlorhexidine, systèmes de résine et articles
JPWO2019194220A1 (ja) * 2018-04-06 2021-05-13 日本曹達株式会社 （ヘテロ）アリールスルホンアミド化合物および有害生物防除剤

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1578644A (fr) * 1967-09-02 1969-08-14
US3637731A (en) * 1968-07-18 1972-01-25 Du Pont 1-(alkylsubstituted phenyl)imidazoles useful in acth reserve assay
US4172947A (en) * 1977-01-07 1979-10-30 Westwood Pharmaceuticals, Inc. 1-(2-Acylaminophenyl)imidazoles
US4284641A (en) * 1977-08-26 1981-08-18 Burroughs Wellcome Co. Pharmaceutically active imidazole derivatives
US4431815A (en) * 1977-08-26 1984-02-14 Burroughs Wellcome Co. 1-[3-(2,4-Dichlorophenyl)propyl]imidazole and salts thereof
SE447653B (sv) * 1978-11-14 1986-12-01 Eisai Co Ltd Imidazolderivat samt farmaceutisk komposition innehallande sadant derivat

Also Published As

Publication number Publication date
SE7909371L (sv) 1980-05-15
US4602031A (en) 1986-07-22
NL7908331A (nl) 1980-05-19
IT1127223B (it) 1986-05-21
US4301169A (en) 1981-11-17
GB2044754B (en) 1983-05-05
FR2441616A1 (fr) 1980-06-13
GB2044754A (en) 1980-10-22
SE447653B (sv) 1986-12-01
US4402966A (en) 1983-09-06
CH642635A5 (fr) 1984-04-30
US4533669A (en) 1985-08-06
CA1126272A (fr) 1982-06-22
IT7927268A0 (it) 1979-11-14
DE2946020A1 (de) 1980-05-29

Similar Documents

Publication Publication Date Title
FR2441616B1 (fr) Nouvel imidazole, procede pour sa preparation et son application therapeutique
BE876455A (fr) Procede de therapeutique anxiolytique
FR2487353B1 (fr) Derives d'hydantoine, leur procede de preparation et leur application therapeutique
BE878723A (fr) Derives de 4-anilinoquinazoline, leur procede de preparation et leur application en therapeutique
BE875174A (fr) Nouveaux derives de carbostyrile, leur procede de preparation et leurs applications en therapeutique
BE890331A (fr) Maleate de 2-amino-3-carbethoxyamino-6-(p-fluoro-benzylamino)pyridine, procede pour sa preparation et son application comme medicament
LU81482A1 (fr) Procede de preparation de d-camphorate de l-carnitinamide et de d-camphorate de d-carnitinamide
FR2532648B1 (fr) Derives de carbostyrile, leur procede de preparation et leur application en therapeutique
BE851893A (fr) Nouvelles aryl-3 oxazolidinones-2, leur procede de preparation et leur application en therapeutique
BE854268A (fr) Pyrrolidones, leur procede de preparation et leur application therapeutique
FR2458547B2 (fr) Nouvelles n-aryle azolones, leur procede de preparation et leur application en therapeutique
BE841747A (fr) Ether 1,2,2,2,-tetrafluoroethyl-fluoromethylique, son procede de preparation et son application
FR2349587A1 (fr) 1,3-dihydro-heteroarylspiro(isobenzofurannes), leur procede de preparation et leur application therapeutique
FR2351965A1 (fr) Benzenesulfonylurees, leur procede de preparation et leur application therapeutique
BE883713A (fr) Nouveau derives de carbostyrile, leur procede de preparation et leur application en therapeutique
BE878127A (fr) Amides 1,2,3-triazolecarboxyliques, leur procede de preparation et leur utilisation
BE880615A (fr) Nouveau derive du paracetamol, son procede de preparation et son utilisation en therapeutique
BE861107A (fr) P-isobutyl-hydratropate de gaiacol et procede pour sa preparation
MA18466A1 (fr) Fongicides et procede pour leur preparation
BE880292A (fr) Nouveaux acides oxy-cyclohexylacetiques substitues, leur procede de preparation et leur application en therapeutique
BE876909A (fr) Sel sodique de mercaptopropionylglycine, procede pour sa preparation et utilisations therapeutiques
ZA79271B (en) 1-naphthyl-acetic acid derivatives,process for their preparation and their therapeutic applications
BE880031A (fr) Procede pour la preparation de 1 alpha, 3 beta-dihydroxy-delta 5-steroides
DE2962151D1 (en) Bis-n-dialkylcarbamyl-quinacridones, process for their preparation and their application
RO76126A2 (fr) PROCEDE POUR LA PREPARATION DES ACIDES ANTHRAQUINONE-2,6 ET 2,7-œISULFONIQUES

Legal Events

Date Code Title Description
ST Notification of lapse