FR2439767A1 - Composes cyclo-aliphatiques utiles comme medicaments - Google Patents

Composes cyclo-aliphatiques utiles comme medicaments

Info

Publication number
FR2439767A1
FR2439767A1 FR7926223A FR7926223A FR2439767A1 FR 2439767 A1 FR2439767 A1 FR 2439767A1 FR 7926223 A FR7926223 A FR 7926223A FR 7926223 A FR7926223 A FR 7926223A FR 2439767 A1 FR2439767 A1 FR 2439767A1
Authority
FR
France
Prior art keywords
group
hydrogen
compounds
hydrogen atom
alcenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7926223A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of FR2439767A1 publication Critical patent/FR2439767A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/24—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/26—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Emergency Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

LA PRESENTE INVENTION CONCERNE DES COMPOSES CHIMIQUES NOUVEAUX ET LEUR PREPARATION. IL S'AGIT DE COMPOSES DE FORMULE GENERALE: (CF DESSIN DANS BOPI) DANS LAQUELLE R REPRESENTE UN ATOME D'HYDROGENE, UN ATOME D'HALOGENE OU UN GROUPE OR, DANS LEQUEL R REPRESENTE UN ATOME D'HYDROGENE, UN GROUPE ALCOYLE OU UN GROUPE ACYLE, R REPRESENTE DE L'HYDROGENE OU UN GROUPE ALCOYLE, ALCENYLE OU ARYLE, R ET R, QUI PEUVENT ETRE IDENTIQUES OU DIFFERENTS, REPRESENTENT CHACUN UN ATOME D'HYDROGENE OU UN GROUPE ALCOYLE, ALCENYLE OU ALCYNYLE EVENTUELLEMENT SUBSTITUE PAR UN GROUPE ARYLE OU CYCLOALCOYLE; OU R ET R FORMENT AVEC L'ATOME D'AZOTE UN NOYAU SATURE DE 4 A 7CHAINONS, AVEC LES CONDITIONS QUE, QUAND R ET R REPRESENTENT SIMULTANEMENT DES ATOMES D'HYDROGENE, ALORS QUAND R EST DE L'HYDROGENE, R NE DOIT PAS ETRE UN GROUPE METHYLE ET LES COMPOSES SONT LES ISOMERES BETA; ET DE LEURS SELS PHYSIOLOGIQUEMENT ACCEPTABLES. LES COMPOSES DE FORMULE SONT UTILES COMME MEDICAMENTS.
FR7926223A 1978-10-25 1979-10-23 Composes cyclo-aliphatiques utiles comme medicaments Withdrawn FR2439767A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7841873 1978-10-25
GB7841871 1978-10-25

Publications (1)

Publication Number Publication Date
FR2439767A1 true FR2439767A1 (fr) 1980-05-23

Family

ID=26269317

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7926223A Withdrawn FR2439767A1 (fr) 1978-10-25 1979-10-23 Composes cyclo-aliphatiques utiles comme medicaments

Country Status (13)

Country Link
US (1) US4291059A (fr)
AT (1) ATA690279A (fr)
AU (1) AU5196679A (fr)
CA (1) CA1126283A (fr)
DE (1) DE2942644A1 (fr)
DK (1) DK448979A (fr)
ES (2) ES485392A1 (fr)
FI (1) FI793268A (fr)
FR (1) FR2439767A1 (fr)
IT (1) IT1164744B (fr)
NL (1) NL7907870A (fr)
NZ (1) NZ191898A (fr)
SE (1) SE7908810L (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0155721A1 (fr) * 1984-02-28 1985-09-25 Akzo N.V. Amino-alcools anti-arythmiques

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8716278D0 (en) * 1987-07-10 1987-08-19 Fujisawa Pharmaceutical Co Antimicrobial agent

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0155721A1 (fr) * 1984-02-28 1985-09-25 Akzo N.V. Amino-alcools anti-arythmiques

Also Published As

Publication number Publication date
ES8204983A1 (es) 1982-05-16
ATA690279A (de) 1982-10-15
ES491975A0 (es) 1982-05-16
CA1126283A (fr) 1982-06-22
US4291059A (en) 1981-09-22
DK448979A (da) 1980-05-30
FI793268A (fi) 1980-04-26
ES485392A1 (es) 1980-10-01
IT7950665A0 (it) 1979-10-24
IT1164744B (it) 1987-04-15
AU5196679A (en) 1980-05-01
DE2942644A1 (de) 1980-05-08
SE7908810L (sv) 1980-04-26
NZ191898A (en) 1982-08-17
NL7907870A (nl) 1980-04-29

Similar Documents

Publication Publication Date Title
FR2453853A1 (fr) Nouveaux derives d'o-(4-diphenylmethylpiperidino)-alcanophenones utiles notamment comme antihistaminiques, et leur procede de preparation
FR2384753A1 (fr) Nouveaux thiols et leur procede de preparation
FR2441625A1 (fr) (d2-imidazolinyl-2 amino)-5 pyrimidines, procede pour les preparer, et medicaments qui en contiennent
OA04910A (fr) Procédé de préparation de nouveaux dérivés d'acide oxy-16 prostanoïque.
FR2378023A1 (fr) Procede de preparation d'oximes, nouveaux produits ainsi obtenus et leur application dans la synthese de composes d'acide cephemcarboxylique 3,7-disubstitue
FR2447376A1 (fr) Nouveaux derives de 1,2-dihydro-2-oxo-4-phenyl-3-quinoleinecarbonitrile, utiles notamment comme agents anti-inflammatoires
LTIP903A (en) Preparation process of solid pharmaceutical forms and such forms
OA05593A (fr) Nouveaux dérivés d'acide 4,5-dichlorimidazole-2- carboxylique, leur procédé de préparation et leur application comme pesticides.
FR2394546A1 (fr) Nouveaux derives de 1,2,3,4,6,7-hexahydro-11bah-benzo(a)-quinolizine, leur preparation et leur application en tant que medicaments
FR2506772A1 (fr) Glycosides d'anthracycline, procede pour les preparer et leur usage comme medicament
ZA879280B (en) Basically substituted phenylacetonitriles,their preparation and drugs containing these compounds
FR2366285A1 (fr) (3-amino-5-substitue-6-fluoropyrazinoyl ou pyrazamido) guanidines et leurs derives portant des substituants sur les atomes d'azote du noyau de guanidine, utiles comme medicaments
FR2439767A1 (fr) Composes cyclo-aliphatiques utiles comme medicaments
FR2422405A1 (fr) Nouveaux medicaments constitues de derives de l'acide p-aminobenzoique
FR2340902A1 (fr) Procede de preparation d'acide phosphorique pur
FR2438048A1 (fr) Nouveaux derives de 1,3-oxazino (5,6-c) rifamycine doues d'une activite antibiotique
FR2413358A1 (fr) Nouveaux derives de 2-aminomethylphenol, utiles notamment comme agents anti-inflammatoires, et leur procede de preparation
FR2457867A1 (fr) Nouveaux derives d'hydroxyamino-eburnane : leur procede de preparation, intermediaires utilises et utilisation comme medicament et comme intermediaire
FR2437405A1 (fr) Nouveaux alcoylbenzenes substitues basiques utiles comme medicaments
FR2320262A1 (fr) Procede de preparation de phosphates a partir d'acide phosphorique
FR2415096A1 (fr) Nouveaux derives de bis(nitrosoureido)-polyols et leur procede de preparation
FR2448536A1 (fr) Nouveaux derives de 2-hydroxymethyl-pyrazine, et leur procede de preparation
OA06258A (fr) Procédé de préparation de nouveaux dérivés acétyléniques de l'androst-4-ène.
DE2963730D1 (en) 1,4-dihydropyridazine-3-carbonyl compounds, process for their preparation, the compounds for use in curing diseases, medicaments containing them and process for the preparation of the medicaments
ZA793720B (en) Substituted 2-phenylamino-imidazoline-(2)derivatives,acid addition salts thereof,processes for their preparation,and pharmaceutical compositions thereof

Legal Events

Date Code Title Description
ST Notification of lapse