FR2439185A1 - Procede - Google Patents

Procede

Info

Publication number
FR2439185A1
FR2439185A1 FR7925757A FR7925757A FR2439185A1 FR 2439185 A1 FR2439185 A1 FR 2439185A1 FR 7925757 A FR7925757 A FR 7925757A FR 7925757 A FR7925757 A FR 7925757A FR 2439185 A1 FR2439185 A1 FR 2439185A1
Authority
FR
France
Prior art keywords
substitute
pyrrole
amine
acetone
reactional
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
FR7925757A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mallinckrodt Inc
Original Assignee
Mallinckrodt Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc
Publication of FR2439185A1 publication Critical patent/FR2439185A1/fr
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDE AMELIORE DE FABRICATION DE DIESTERS DE PYRROLE SUBSTITUES, CONSISTANT A FAIRE REAGIR UNE AMINE PRIMAIRE AVEC UN DIESTER DE L'ACIDE ACETONE DICARBOXYLIQUE ET UN COMPOSE CARBONYLE SUBSTITUE TEL QUE LA CHLORACETONE. ON MENE LA REACTION DE FORMATION DE L'ESTER DE PYRROLE DANS UNE DISPERSION DE MILIEU REACTIONNEL BIPHASIQUE AQUEUX-ORGANIQUE, CONTENANT L'AMINE, AVEC LAQUELLE ON COMBINE LE DIESTER DE L'ACIDE ACETONE CARBOXYLIQUE ET LE COMPOSE CARBONYLE SUBSTITUE, ETOU DANS UN MILIEU REACTIONNEL CONTENANT L'AMINE, AUQUEL ON AJOUTE L'ESTER DE L'ACIDE ACETONE DICARBOXYLIQUE ET LE COMPOSE CARBONYLE SUBSTITUE, D'UNE MANIERE PRATIQUEMENT SIMULTANEE. LES DIESTERS DE PYRROLE OBTENUS PERMETTENT DE PREPARER DES PYRROLE-2-ACETATES A SUBSTITUANTS ALKYLE ET AROYLE, QUI SONT DES AGENTS ANTI-INFLAMMATOIRES.
FR7925757A 1978-10-19 1979-10-17 Procede Pending FR2439185A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95271178A 1978-10-19 1978-10-19
US95268278A 1978-10-19 1978-10-19

Publications (1)

Publication Number Publication Date
FR2439185A1 true FR2439185A1 (fr) 1980-05-16

Family

ID=27130329

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7925757A Pending FR2439185A1 (fr) 1978-10-19 1979-10-17 Procede

Country Status (7)

Country Link
CA (1) CA1105039A (fr)
DE (1) DE2942140A1 (fr)
FI (1) FI793221A (fr)
FR (1) FR2439185A1 (fr)
GB (1) GB2034304A (fr)
NL (1) NL7907735A (fr)
SE (1) SE7908596L (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4388468A (en) * 1980-04-04 1983-06-14 Ethyl Corporation Process for producing substituted pyrroles
US4565879A (en) * 1980-04-04 1986-01-21 Ethyl Corporation Process for producing substituted pyrroles
US4455433A (en) * 1981-11-02 1984-06-19 Ethyl Corporation Process for producing substituted pyrroles
US4383117A (en) 1981-11-02 1983-05-10 Ethyl Corporation Process for producing substituted pyrroles
IT1151731B (it) * 1982-04-21 1986-12-24 Montedison Spa Processo per la preparazione dell'acido 3-carbossi-1,4-dimetilpirrol-2-acetico
US4937368A (en) * 1987-01-14 1990-06-26 Syntex (U.S.A.) Inc. Process for preparing (+)-2,3-dihydro-1H-pyrrolo[1,2-A]pyrrole-1,7-dicarboxylates
US4874872A (en) * 1987-01-14 1989-10-17 Syntex (U.S.A.) Inc. Process for preparing (+)-2,3-dihydro-1H-pyrrolo[1,2-A]pyrrole-1,7-dicarboxylates
US4835288A (en) * 1987-01-14 1989-05-30 Syntex Inc. Process for preparing (+)-2,3-dihydro-1H-pyrrolo[1,2-a]pyrrole-1,7-dicarboxylates

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4070368A (en) * 1970-01-26 1978-01-24 Mcneil Laboratories, Incorporated Process for preparing alkyl, aroyl substitute pyrrole-2-acetates

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4070368A (en) * 1970-01-26 1978-01-24 Mcneil Laboratories, Incorporated Process for preparing alkyl, aroyl substitute pyrrole-2-acetates

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EXBK/73 *

Also Published As

Publication number Publication date
NL7907735A (nl) 1980-04-22
DE2942140A1 (de) 1980-04-30
SE7908596L (sv) 1980-04-20
FI793221A (fi) 1980-04-20
GB2034304A (en) 1980-06-04
CA1105039A (fr) 1981-07-14

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