FR2439185A1 - Procede - Google Patents
ProcedeInfo
- Publication number
- FR2439185A1 FR2439185A1 FR7925757A FR7925757A FR2439185A1 FR 2439185 A1 FR2439185 A1 FR 2439185A1 FR 7925757 A FR7925757 A FR 7925757A FR 7925757 A FR7925757 A FR 7925757A FR 2439185 A1 FR2439185 A1 FR 2439185A1
- Authority
- FR
- France
- Prior art keywords
- substitute
- pyrrole
- amine
- acetone
- reactional
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEDE AMELIORE DE FABRICATION DE DIESTERS DE PYRROLE SUBSTITUES, CONSISTANT A FAIRE REAGIR UNE AMINE PRIMAIRE AVEC UN DIESTER DE L'ACIDE ACETONE DICARBOXYLIQUE ET UN COMPOSE CARBONYLE SUBSTITUE TEL QUE LA CHLORACETONE. ON MENE LA REACTION DE FORMATION DE L'ESTER DE PYRROLE DANS UNE DISPERSION DE MILIEU REACTIONNEL BIPHASIQUE AQUEUX-ORGANIQUE, CONTENANT L'AMINE, AVEC LAQUELLE ON COMBINE LE DIESTER DE L'ACIDE ACETONE CARBOXYLIQUE ET LE COMPOSE CARBONYLE SUBSTITUE, ETOU DANS UN MILIEU REACTIONNEL CONTENANT L'AMINE, AUQUEL ON AJOUTE L'ESTER DE L'ACIDE ACETONE DICARBOXYLIQUE ET LE COMPOSE CARBONYLE SUBSTITUE, D'UNE MANIERE PRATIQUEMENT SIMULTANEE. LES DIESTERS DE PYRROLE OBTENUS PERMETTENT DE PREPARER DES PYRROLE-2-ACETATES A SUBSTITUANTS ALKYLE ET AROYLE, QUI SONT DES AGENTS ANTI-INFLAMMATOIRES.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US95268278A | 1978-10-19 | 1978-10-19 | |
US95271178A | 1978-10-19 | 1978-10-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
FR2439185A1 true FR2439185A1 (fr) | 1980-05-16 |
Family
ID=27130329
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7925757A Pending FR2439185A1 (fr) | 1978-10-19 | 1979-10-17 | Procede |
Country Status (7)
Country | Link |
---|---|
CA (1) | CA1105039A (fr) |
DE (1) | DE2942140A1 (fr) |
FI (1) | FI793221A (fr) |
FR (1) | FR2439185A1 (fr) |
GB (1) | GB2034304A (fr) |
NL (1) | NL7907735A (fr) |
SE (1) | SE7908596L (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4388468A (en) * | 1980-04-04 | 1983-06-14 | Ethyl Corporation | Process for producing substituted pyrroles |
US4565879A (en) * | 1980-04-04 | 1986-01-21 | Ethyl Corporation | Process for producing substituted pyrroles |
US4383117A (en) | 1981-11-02 | 1983-05-10 | Ethyl Corporation | Process for producing substituted pyrroles |
US4455433A (en) * | 1981-11-02 | 1984-06-19 | Ethyl Corporation | Process for producing substituted pyrroles |
IT1151731B (it) * | 1982-04-21 | 1986-12-24 | Montedison Spa | Processo per la preparazione dell'acido 3-carbossi-1,4-dimetilpirrol-2-acetico |
US4937368A (en) * | 1987-01-14 | 1990-06-26 | Syntex (U.S.A.) Inc. | Process for preparing (+)-2,3-dihydro-1H-pyrrolo[1,2-A]pyrrole-1,7-dicarboxylates |
US4835288A (en) * | 1987-01-14 | 1989-05-30 | Syntex Inc. | Process for preparing (+)-2,3-dihydro-1H-pyrrolo[1,2-a]pyrrole-1,7-dicarboxylates |
US4874872A (en) * | 1987-01-14 | 1989-10-17 | Syntex (U.S.A.) Inc. | Process for preparing (+)-2,3-dihydro-1H-pyrrolo[1,2-A]pyrrole-1,7-dicarboxylates |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4070368A (en) * | 1970-01-26 | 1978-01-24 | Mcneil Laboratories, Incorporated | Process for preparing alkyl, aroyl substitute pyrrole-2-acetates |
-
1979
- 1979-09-27 CA CA336,509A patent/CA1105039A/fr not_active Expired
- 1979-10-17 FI FI793221A patent/FI793221A/fi not_active Application Discontinuation
- 1979-10-17 SE SE7908596A patent/SE7908596L/xx not_active Application Discontinuation
- 1979-10-17 FR FR7925757A patent/FR2439185A1/fr active Pending
- 1979-10-18 DE DE19792942140 patent/DE2942140A1/de not_active Withdrawn
- 1979-10-18 GB GB7936183A patent/GB2034304A/en not_active Withdrawn
- 1979-10-19 NL NL7907735A patent/NL7907735A/nl not_active Application Discontinuation
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4070368A (en) * | 1970-01-26 | 1978-01-24 | Mcneil Laboratories, Incorporated | Process for preparing alkyl, aroyl substitute pyrrole-2-acetates |
Non-Patent Citations (1)
Title |
---|
EXBK/73 * |
Also Published As
Publication number | Publication date |
---|---|
NL7907735A (nl) | 1980-04-22 |
SE7908596L (sv) | 1980-04-20 |
DE2942140A1 (de) | 1980-04-30 |
FI793221A (fi) | 1980-04-20 |
CA1105039A (fr) | 1981-07-14 |
GB2034304A (en) | 1980-06-04 |
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