FR2434172A1 - Nouveaux composes intermediaires utiles dans la synthese de derives bis-indoliques et procede pour leur preparation - Google Patents

Nouveaux composes intermediaires utiles dans la synthese de derives bis-indoliques et procede pour leur preparation

Info

Publication number
FR2434172A1
FR2434172A1 FR7824569A FR7824569A FR2434172A1 FR 2434172 A1 FR2434172 A1 FR 2434172A1 FR 7824569 A FR7824569 A FR 7824569A FR 7824569 A FR7824569 A FR 7824569A FR 2434172 A1 FR2434172 A1 FR 2434172A1
Authority
FR
France
Prior art keywords
derivs
vinblastine
vincristine
hydroxy
alkanoyloxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7824569A
Other languages
English (en)
French (fr)
Other versions
FR2434172B1 (ja
Inventor
Pierre Potier
Nicole Langlois
Yves Langlois
Pierre Mangeney
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bpifrance Financement SA
Original Assignee
Agence National de Valorisation de la Recherche ANVAR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agence National de Valorisation de la Recherche ANVAR filed Critical Agence National de Valorisation de la Recherche ANVAR
Priority to FR7824569A priority Critical patent/FR2434172A1/fr
Priority to US06/067,439 priority patent/US4307100A/en
Priority to JP10704579A priority patent/JPS5531096A/ja
Priority to HU79RE655A priority patent/HU182988B/hu
Priority to CA000334286A priority patent/CA1136129A/fr
Priority to EP79400585A priority patent/EP0010458B1/fr
Priority to DE7979400585T priority patent/DE2966049D1/de
Publication of FR2434172A1 publication Critical patent/FR2434172A1/fr
Application granted granted Critical
Publication of FR2434172B1 publication Critical patent/FR2434172B1/fr
Priority to NL990027C priority patent/NL990027I2/nl
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FR7824569A 1978-08-24 1978-08-24 Nouveaux composes intermediaires utiles dans la synthese de derives bis-indoliques et procede pour leur preparation Granted FR2434172A1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FR7824569A FR2434172A1 (fr) 1978-08-24 1978-08-24 Nouveaux composes intermediaires utiles dans la synthese de derives bis-indoliques et procede pour leur preparation
US06/067,439 US4307100A (en) 1978-08-24 1979-08-20 Nor bis-indole compounds usable as medicaments
HU79RE655A HU182988B (en) 1978-08-24 1979-08-22 Process for preparing bis-indole compounds
CA000334286A CA1136129A (fr) 1978-08-24 1979-08-22 Composes intermediaires utiles dans la synthese de derives bis-indoliques et procede pour leur preparation
JP10704579A JPS5531096A (en) 1978-08-24 1979-08-22 Novel compound bissindoline derivative active as drug and its manufacture
EP79400585A EP0010458B1 (fr) 1978-08-24 1979-08-23 Composés bis-indoliques, compositions pharmaceutiques les contenant, procédé pour leur préparation
DE7979400585T DE2966049D1 (en) 1978-08-24 1979-08-23 Bis-indole compounds, pharmaceutical compositions containing them, process for their preparation
NL990027C NL990027I2 (nl) 1978-08-24 1999-08-20 Bisindoolverbindingen, farmaceutische preparaten die hen bevatten en werkwijze voor hun bereiding.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7824569A FR2434172A1 (fr) 1978-08-24 1978-08-24 Nouveaux composes intermediaires utiles dans la synthese de derives bis-indoliques et procede pour leur preparation

Publications (2)

Publication Number Publication Date
FR2434172A1 true FR2434172A1 (fr) 1980-03-21
FR2434172B1 FR2434172B1 (ja) 1981-01-30

Family

ID=9212050

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7824569A Granted FR2434172A1 (fr) 1978-08-24 1978-08-24 Nouveaux composes intermediaires utiles dans la synthese de derives bis-indoliques et procede pour leur preparation

Country Status (2)

Country Link
JP (1) JPS5531096A (ja)
FR (1) FR2434172A1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0022730A1 (fr) * 1979-07-17 1981-01-21 ANVAR Agence Nationale de Valorisation de la Recherche Nouvelle classe de composés bis-indoliques utiles comme médicaments et procédé pour leur préparation

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6660709B1 (en) 1998-12-12 2003-12-09 Solvay (Societe Anonyme) Compositions comprising 1,1,1,3,3-pentafluorobutane and use of these compositions
EP1989212B1 (en) * 2006-02-17 2013-06-19 Cascade Prodrug Inc. Treatment of hyperproliferative diseases with vinca alkaloid n-oxide and analogs
CN101235046B (zh) * 2007-01-29 2010-09-08 中国科学院上海药物研究所 长春碱衍生物、其制备方法和用途、以及包含该衍生物的药物组合物

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1435519A (fr) * 1964-06-18 1966-04-15 Lilly Co Eli Indolylvindoline et procédé de préparation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1435519A (fr) * 1964-06-18 1966-04-15 Lilly Co Eli Indolylvindoline et procédé de préparation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0022730A1 (fr) * 1979-07-17 1981-01-21 ANVAR Agence Nationale de Valorisation de la Recherche Nouvelle classe de composés bis-indoliques utiles comme médicaments et procédé pour leur préparation

Also Published As

Publication number Publication date
JPS6332795B2 (ja) 1988-07-01
FR2434172B1 (ja) 1981-01-30
JPS5531096A (en) 1980-03-05

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Legal Events

Date Code Title Description
CC Supplementary protection certificate (spc) laid open to the public (law of 25 june 1990)

Free format text: 92C0390, 920604

CB Supplementary protection certificate (spc) granted (law of 25 june 1990)

Free format text: 92C0390, 780824

CL Concession to grant licences
TP Transmission of property