FR2419274A1 - Pleuromutilin solvates with a halogenated aliphatic hydrocarbon - useful for purifying crude pleuromutilin antibiotic - Google Patents

Pleuromutilin solvates with a halogenated aliphatic hydrocarbon - useful for purifying crude pleuromutilin antibiotic

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Publication number
FR2419274A1
FR2419274A1 FR7806420A FR7806420A FR2419274A1 FR 2419274 A1 FR2419274 A1 FR 2419274A1 FR 7806420 A FR7806420 A FR 7806420A FR 7806420 A FR7806420 A FR 7806420A FR 2419274 A1 FR2419274 A1 FR 2419274A1
Authority
FR
France
Prior art keywords
pleuromutilin
useful
aliphatic hydrocarbon
solvate
halogenated aliphatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7806420A
Other languages
French (fr)
Other versions
FR2419274B1 (en
Inventor
Franz Knauseder
Helmuth Wagner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz GmbH
Original Assignee
Biochemie GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biochemie GmbH filed Critical Biochemie GmbH
Priority to FR7806420A priority Critical patent/FR2419274A1/en
Publication of FR2419274A1 publication Critical patent/FR2419274A1/en
Application granted granted Critical
Publication of FR2419274B1 publication Critical patent/FR2419274B1/fr
Granted legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A solvate of pleuromutilin (I) with a halogenated aliphatic hydrocarbon (II) in the molar ratio of 1:1, is new. The solvate is useful for purifying (I), thus crude (I) can be converted into its solvate and which can be converted to pure (I) by e.g., heating. (I) is known antibiotic which can be converted into other pleuromutilin derivs. In an example, a solvate is prepd. by dissolving crude (I) in 1,1,1-trichloroethane, filtering off the insoluble impurities, cooling for 24 hrs. when the solvate crystallises out.
FR7806420A 1978-03-07 1978-03-07 Pleuromutilin solvates with a halogenated aliphatic hydrocarbon - useful for purifying crude pleuromutilin antibiotic Granted FR2419274A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7806420A FR2419274A1 (en) 1978-03-07 1978-03-07 Pleuromutilin solvates with a halogenated aliphatic hydrocarbon - useful for purifying crude pleuromutilin antibiotic

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7806420A FR2419274A1 (en) 1978-03-07 1978-03-07 Pleuromutilin solvates with a halogenated aliphatic hydrocarbon - useful for purifying crude pleuromutilin antibiotic

Publications (2)

Publication Number Publication Date
FR2419274A1 true FR2419274A1 (en) 1979-10-05
FR2419274B1 FR2419274B1 (en) 1984-01-13

Family

ID=9205422

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7806420A Granted FR2419274A1 (en) 1978-03-07 1978-03-07 Pleuromutilin solvates with a halogenated aliphatic hydrocarbon - useful for purifying crude pleuromutilin antibiotic

Country Status (1)

Country Link
FR (1) FR2419274A1 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4089891A (en) * 1975-07-23 1978-05-16 Biochemie Pleuromutilin solvates

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4089891A (en) * 1975-07-23 1978-05-16 Biochemie Pleuromutilin solvates

Also Published As

Publication number Publication date
FR2419274B1 (en) 1984-01-13

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