FR2418239A1 - L-lysine a-oxydase, sa preparation et son emploi pour le dosage de la l-lysine et comme agent therapeutique - Google Patents
L-lysine a-oxydase, sa preparation et son emploi pour le dosage de la l-lysine et comme agent therapeutiqueInfo
- Publication number
- FR2418239A1 FR2418239A1 FR7904967A FR7904967A FR2418239A1 FR 2418239 A1 FR2418239 A1 FR 2418239A1 FR 7904967 A FR7904967 A FR 7904967A FR 7904967 A FR7904967 A FR 7904967A FR 2418239 A1 FR2418239 A1 FR 2418239A1
- Authority
- FR
- France
- Prior art keywords
- lysine
- oxydase
- determination
- preparation
- therapeutic agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 title abstract 4
- 239000003814 drug Substances 0.000 title 1
- 229940124597 therapeutic agent Drugs 0.000 title 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 2
- 230000000259 anti-tumor effect Effects 0.000 abstract 2
- SLXKOJJOQWFEFD-UHFFFAOYSA-N 6-aminohexanoic acid Chemical compound NCCCCCC(O)=O SLXKOJJOQWFEFD-UHFFFAOYSA-N 0.000 abstract 1
- 108010008292 L-Amino Acid Oxidase Proteins 0.000 abstract 1
- 235000019766 L-Lysine Nutrition 0.000 abstract 1
- 102000007070 L-amino-acid oxidase Human genes 0.000 abstract 1
- 108010004733 L-lysine oxidase Proteins 0.000 abstract 1
- 239000004472 Lysine Substances 0.000 abstract 1
- 241000223259 Trichoderma Species 0.000 abstract 1
- 150000004716 alpha keto acids Chemical class 0.000 abstract 1
- 229960002684 aminocaproic acid Drugs 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- WPLOVIFNBMNBPD-ATHMIXSHSA-N subtilin Chemical compound CC1SCC(NC2=O)C(=O)NC(CC(N)=O)C(=O)NC(C(=O)NC(CCCCN)C(=O)NC(C(C)CC)C(=O)NC(=C)C(=O)NC(CCCCN)C(O)=O)CSC(C)C2NC(=O)C(CC(C)C)NC(=O)C1NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C1NC(=O)C(=C/C)/NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C2NC(=O)CNC(=O)C3CCCN3C(=O)C(NC(=O)C3NC(=O)C(CC(C)C)NC(=O)C(=C)NC(=O)C(CCC(O)=O)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(N)CC=4C5=CC=CC=C5NC=4)CSC3)C(C)SC2)C(C)C)C(C)SC1)CC1=CC=CC=C1 WPLOVIFNBMNBPD-ATHMIXSHSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
- C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y104/00—Oxidoreductases acting on the CH-NH2 group of donors (1.4)
- C12Y104/03—Oxidoreductases acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
- C12Y104/03014—L-Lysine oxidase (1.4.3.14)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2099378A JPS54117089A (en) | 1978-02-27 | 1978-02-27 | Preparation of lllysine oxidase |
| JP7344178A JPS5571A (en) | 1978-06-16 | 1978-06-16 | Lllysine oxidase |
| JP11586778A JPS5543409A (en) | 1978-09-22 | 1978-09-22 | Estimation method of l-lysine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2418239A1 true FR2418239A1 (fr) | 1979-09-21 |
| FR2418239B1 FR2418239B1 (enExample) | 1983-07-18 |
Family
ID=27283250
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7904967A Granted FR2418239A1 (fr) | 1978-02-27 | 1979-02-27 | L-lysine a-oxydase, sa preparation et son emploi pour le dosage de la l-lysine et comme agent therapeutique |
Country Status (4)
| Country | Link |
|---|---|
| CA (1) | CA1111790A (enExample) |
| DE (2) | DE2954471C2 (enExample) |
| FR (1) | FR2418239A1 (enExample) |
| GB (1) | GB2015532B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0138040A3 (en) * | 1983-09-16 | 1987-08-05 | Hoechst Aktiengesellschaft | L-amino-acid oxidase from yeasts of the genus cryptococcus, its preparation and use |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2015532B (en) * | 1978-02-27 | 1982-06-16 | Yamasa Shoyu Kk | -lysine -oxidase |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2304846A1 (de) * | 1973-02-01 | 1974-08-08 | Bayer Ag | Verfahren zur anreicherung und reinigung von l-lysinoxygenase, sowie ihre verwendung als arzneimittel |
| FR2359850A1 (fr) * | 1976-07-27 | 1978-02-24 | Boehringer Mannheim Gmbh | Nicotinamide-adenine-dinucleotide reduite (nadh) peroxydase, son obtention et son utilisation |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2015532B (en) | 1978-02-27 | 1982-06-16 | Yamasa Shoyu Kk | -lysine -oxidase |
-
1979
- 1979-02-19 GB GB7905850A patent/GB2015532B/en not_active Expired
- 1979-02-21 DE DE19792954471 patent/DE2954471C2/de not_active Expired
- 1979-02-21 DE DE19792906737 patent/DE2906737C2/de not_active Expired
- 1979-02-26 CA CA322,273A patent/CA1111790A/en not_active Expired
- 1979-02-27 FR FR7904967A patent/FR2418239A1/fr active Granted
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2304846A1 (de) * | 1973-02-01 | 1974-08-08 | Bayer Ag | Verfahren zur anreicherung und reinigung von l-lysinoxygenase, sowie ihre verwendung als arzneimittel |
| FR2359850A1 (fr) * | 1976-07-27 | 1978-02-24 | Boehringer Mannheim Gmbh | Nicotinamide-adenine-dinucleotide reduite (nadh) peroxydase, son obtention et son utilisation |
Non-Patent Citations (3)
| Title |
|---|
| CA1958 * |
| CA1961 * |
| EXBK/74 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0138040A3 (en) * | 1983-09-16 | 1987-08-05 | Hoechst Aktiengesellschaft | L-amino-acid oxidase from yeasts of the genus cryptococcus, its preparation and use |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2906737A1 (de) | 1979-08-30 |
| DE2954471C2 (enExample) | 1989-06-22 |
| FR2418239B1 (enExample) | 1983-07-18 |
| CA1111790A (en) | 1981-11-03 |
| GB2015532B (en) | 1982-06-16 |
| DE2906737C2 (de) | 1986-08-21 |
| GB2015532A (en) | 1979-09-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |