FR2413094A1 - Nouvel antibiotique du type peptide utilisable comme medicament et procede pour le preparer - Google Patents

Nouvel antibiotique du type peptide utilisable comme medicament et procede pour le preparer

Info

Publication number
FR2413094A1
FR2413094A1 FR7836441A FR7836441A FR2413094A1 FR 2413094 A1 FR2413094 A1 FR 2413094A1 FR 7836441 A FR7836441 A FR 7836441A FR 7836441 A FR7836441 A FR 7836441A FR 2413094 A1 FR2413094 A1 FR 2413094A1
Authority
FR
France
Prior art keywords
peptide type
preparing
new antibiotic
medicinal product
type usable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7836441A
Other languages
English (en)
Other versions
FR2413094B1 (fr
Inventor
Shigeji Kondo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kaken Pharmaceutical Co Ltd
Original Assignee
Kakenyaku Kako KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kakenyaku Kako KK filed Critical Kakenyaku Kako KK
Publication of FR2413094A1 publication Critical patent/FR2413094A1/fr
Application granted granted Critical
Publication of FR2413094B1 publication Critical patent/FR2413094B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/145Fungal isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/645Fungi ; Processes using fungi
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/19Antibiotic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'INVENTION A POUR OBJET UN NOUVEL ANTIBIOTIQUE APPELE K 582 M DU TYPE PEPTIDE A CHAINE DROITE. ON L'OBTIENT EN CULTIVANT UN MICROORGANISME DU GENRE METARHIZIUM TEL QUE LE METAHIZIUM ANISOPLIAE (METSCH) SOROK. VAR. ANISOPLIAE 582 M QUI DONNE UNE SUBSTANCE AYANT LES CONSTITUANTS SUIVANTS: ARGININE 1, THREONINE 1, TYROSINE 1, ORNITHINE 2, HYDROXYARGININE M, LYSINE N SEPARABLE EN DEUX VARIETES A (M 1, N 1) ET B (M 2, N 0). CET ANTIBIOTIQUE INHIBE LA CROISSANCE DE DIVERS MYCETES ET DIVERS VIRUS; IL A UNE ACTIVITE ANTITUMORALE ET UN EFFET SUR LE SYSTEME IMMUNITAIRE DES CORPS VIVANTS. LE SPECTRE IR DE K-582-M - A EST DONNE PAR LA FIGURE 1.
FR7836441A 1977-12-28 1978-12-27 Nouvel antibiotique du type peptide utilisable comme medicament et procede pour le preparer Granted FR2413094A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15741677A JPS5492914A (en) 1977-12-28 1977-12-28 Novel peptide antibiotic substance and its manufacture

Publications (2)

Publication Number Publication Date
FR2413094A1 true FR2413094A1 (fr) 1979-07-27
FR2413094B1 FR2413094B1 (fr) 1982-09-03

Family

ID=15649148

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7836441A Granted FR2413094A1 (fr) 1977-12-28 1978-12-27 Nouvel antibiotique du type peptide utilisable comme medicament et procede pour le preparer

Country Status (13)

Country Link
US (1) US4221705A (fr)
JP (1) JPS5492914A (fr)
AU (1) AU518767B2 (fr)
CA (1) CA1115223A (fr)
DE (1) DE2856410C2 (fr)
ES (1) ES476430A1 (fr)
FR (1) FR2413094A1 (fr)
GB (1) GB2011425B (fr)
LU (1) LU80729A1 (fr)
NL (1) NL175294C (fr)
NZ (1) NZ189313A (fr)
SE (1) SE432589B (fr)
SU (1) SU786915A3 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7135191B2 (en) * 1997-09-04 2006-11-14 Zsolt Istvan Hertelendy Urogenital or anorectal transmucosal vaccine delivery system
CA2611972A1 (fr) * 2005-06-27 2007-01-04 Nippon Kayaku Kabushiki Kaisha Substance physiologiquement active nk13650p3, procede de production de celle-ci et utilisation de celle-ci

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EXBK/75 *

Also Published As

Publication number Publication date
SE432589B (sv) 1984-04-09
JPS5492914A (en) 1979-07-23
AU518767B2 (en) 1981-10-22
CA1115223A (fr) 1981-12-29
LU80729A1 (fr) 1980-01-22
GB2011425A (en) 1979-07-11
NZ189313A (en) 1981-10-19
NL7812616A (nl) 1979-07-02
SU786915A3 (ru) 1980-12-07
AU4293978A (en) 1979-07-05
SE7813269L (sv) 1979-06-29
DE2856410C2 (de) 1983-01-05
NL175294C (nl) 1984-10-16
JPS5744664B2 (fr) 1982-09-22
ES476430A1 (es) 1979-11-16
FR2413094B1 (fr) 1982-09-03
US4221705A (en) 1980-09-09
NL175294B (nl) 1984-05-16
DE2856410A1 (de) 1979-07-05
GB2011425B (en) 1982-06-09

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Legal Events

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