FR2412315A1 - Procede de preparation d'un antigene de l'hepatite b et l'antigene obtenu - Google Patents

Procede de preparation d'un antigene de l'hepatite b et l'antigene obtenu

Info

Publication number
FR2412315A1
FR2412315A1 FR7738613A FR7738613A FR2412315A1 FR 2412315 A1 FR2412315 A1 FR 2412315A1 FR 7738613 A FR7738613 A FR 7738613A FR 7738613 A FR7738613 A FR 7738613A FR 2412315 A1 FR2412315 A1 FR 2412315A1
Authority
FR
France
Prior art keywords
plasma
hepatitis
gradient
concentrating
surface antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7738613A
Other languages
English (en)
Other versions
FR2412315B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB7657/77A external-priority patent/GB1554811A/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Priority to FR7738613A priority Critical patent/FR2412315A1/fr
Publication of FR2412315A1 publication Critical patent/FR2412315A1/fr
Application granted granted Critical
Publication of FR2412315B1 publication Critical patent/FR2412315B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Abstract

LA PRESENTE INVENTION CONCERNE UN PROCEDE DE PREPARATION D'UN ANTIGENE DE L'HEPATITE B ET L'ANTIGENE OBTENU. LE PROCEDE SELON L'INVENTION EST CARACTERISE PAR LE FAIT QUE L'ON SOUMET DU PLASMA CLARIFIE CONTENANT DU HBAG A UN FRACTIONNEMENT ISOPYCNIQUE PARTIEL DANS UN MILIEU LIQUIDE AYANT UN GRADIENT DE DENSITE QUI COMPREND LA DENSITE DE L'ANTIGENE PARTICULIER ISOLE DANS DES CONDITIONS EFFICACES POUR FAIRE PASSER LA QUASI-TOTALITE DU HBAG DU PLASMA CLARIFIE DANS LE GRADIENT DE DENSITE, MAIS INEFFICACES POUR ACHEVER LE FRACTIONNEMENT ISOPYCNIQUE DU HBAG, QUE L'ON ENLEVE LE PLASMA CLARIFIE USE, ET QUE L'ON REPETE AU MOINS UNE FOIS LA PREMIERE ETAPE AVEC UN ECHANTILLON FRAIS DE PLASMA CLARIFIE. APPLICATION A L'INDUSTRIE PHARMACEUTIQUE.
FR7738613A 1977-02-23 1977-12-21 Procede de preparation d'un antigene de l'hepatite b et l'antigene obtenu Granted FR2412315A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7738613A FR2412315A1 (fr) 1977-02-23 1977-12-21 Procede de preparation d'un antigene de l'hepatite b et l'antigene obtenu

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7657/77A GB1554811A (en) 1977-02-23 1977-02-23 Purifying hepatitis b surface antigen
FR7738613A FR2412315A1 (fr) 1977-02-23 1977-12-21 Procede de preparation d'un antigene de l'hepatite b et l'antigene obtenu

Publications (2)

Publication Number Publication Date
FR2412315A1 true FR2412315A1 (fr) 1979-07-20
FR2412315B1 FR2412315B1 (fr) 1980-08-22

Family

ID=26220355

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7738613A Granted FR2412315A1 (fr) 1977-02-23 1977-12-21 Procede de preparation d'un antigene de l'hepatite b et l'antigene obtenu

Country Status (1)

Country Link
FR (1) FR2412315A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2394297A1 (fr) * 1976-11-02 1979-01-12 Merck & Co Inc Particules de dane de l'hepatite b
FR2470795A1 (fr) * 1979-12-07 1981-06-12 Pasteur Institut Procede de purification de particules d'origine biologique, notamment de l'antigene de surface du virus de l'hepatite b (aghbs) et les produits obtenus

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2394297A1 (fr) * 1976-11-02 1979-01-12 Merck & Co Inc Particules de dane de l'hepatite b
FR2422399A1 (fr) * 1976-11-02 1979-11-09 Merck & Co Inc Procede pour la concentration de particules de dane par fractionnement isopycnique
FR2422406A1 (fr) * 1976-11-02 1979-11-09 Merck & Co Inc Composition comprenant un concentrat de particules de dane
FR2470795A1 (fr) * 1979-12-07 1981-06-12 Pasteur Institut Procede de purification de particules d'origine biologique, notamment de l'antigene de surface du virus de l'hepatite b (aghbs) et les produits obtenus

Also Published As

Publication number Publication date
FR2412315B1 (fr) 1980-08-22

Similar Documents

Publication Publication Date Title
ZA762145B (en) Continuous process of recovering pure concentrated ammoni
SE8602869L (sv) Sett och anordning for rening av argon
DE3169689D1 (en) Method of selectively increasing yield and purity of certain cryoprecipitate proteins
IT7951159A0 (it) Procedimento per produrre alluminio di estrema purezza
IT8147789A0 (it) Procedimento per produrre monocristalli purissimi mediante tiraggio da crogiolo secondo czochralski
FR2344629A1 (fr) Procede pour la purification et l'isolement de virus de l'hepatite utilisable pour la preparation d'un vaccin
PT73371A (en) A method for enhancing the yield of hepatitis a virus
FR2412315A1 (fr) Procede de preparation d'un antigene de l'hepatite b et l'antigene obtenu
IT1109399B (it) Procedimento per produrre monocristalli purissimi di silicio
IL49532A (en) Process for reducing cathode deposits upon electrolysis of impure saline solutions
YU89879A (en) Process for recovering cyclohexanone oxime
TR18478A (tr) Yueksek safiyet derecesinde paraksilen' in kurtarilmasi icin tek safhah kristallestirme usulue
GB1541317A (en) Method and apparatus for producing purified water by low temperature distillation
FR2308401A1 (fr) Procede de separation des isotopes de l'uranium par excitation infrarouge
PT67421B (en) Process for recovering gallium from aluminate-alkali solutions resulting from treatment of aluminium-containing ores
SE8003840L (sv) Forfarande for rening av kisel
JPS5434545A (en) Method of producing pure water of high purity
GB1554811A (en) Purifying hepatitis b surface antigen
GB2000773B (en) Process for the purification of phenylhydrozine
JPS5276277A (en) Producing long and narrow crystal
GB942629A (en) Improvements in purification of aluminium
JPS5515341A (en) Method of producing frame rack for bicycle
JPS5266684A (en) Purification and separation of 2-keto-l-glonic acid
SU1734497A1 (ru) Способ удаления углерода-14 из облученного нейтронами графита
JPS5221786A (en) Production process of semiconductor unit

Legal Events

Date Code Title Description
ST Notification of lapse